BS60699
antibody from Bioworld Technology, Inc
Targeting: MARK4
FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS60699 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- MARK4 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human MARK4
- Description
- The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. The serine/threonine (Ser/Thr) protein kinases are a group of proteins that are intimately involved in this process. MARK4 (MAP/microtubule affinity-regulating kinase 4), also known as MARKL1 or KIAA1860, is a 752 amino acid protein that contains one UBA domain, one protein kinase domain and one kinase-associated domain and belongs to the Ser/Thr protein kinase family. Expressed ubiquitously as two alternatively spliced isoforms, one of which is brain-specific, MARK4 uses ATP to catalyze the phosphorylation of target proteins and is thought to be involved in cell growth. MARK4 is upregulated in hepatocellular carcinoma cells, suggesting a role for MARK4 in tumorigenesis.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of MARK4 pAb at 1:500 dilutionLane1:A549 whole cell lysateLane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate