BS60699

antibody from Bioworld Technology, Inc
Targeting: MARK4 FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D
Provider product page for BS60699

Antibody data

Product number
BS60699 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MARK4 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human MARK4
Description
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. The serine/threonine (Ser/Thr) protein kinases are a group of proteins that are intimately involved in this process. MARK4 (MAP/microtubule affinity-regulating kinase 4), also known as MARKL1 or KIAA1860, is a 752 amino acid protein that contains one UBA domain, one protein kinase domain and one kinase-associated domain and belongs to the Ser/Thr protein kinase family. Expressed ubiquitously as two alternatively spliced isoforms, one of which is brain-specific, MARK4 uses ATP to catalyze the phosphorylation of target proteins and is thought to be involved in cell growth. MARK4 is upregulated in hepatocellular carcinoma cells, suggesting a role for MARK4 in tumorigenesis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MARK4 protein structure - BS60699 shown in red.