Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- PA5-77177 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- THRSP Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Low striatal T3 is implicated in inattention and memory impairment in an ADHD mouse model overexpressing thyroid hormone-responsive protein.
Custodio RJP, Kim M, Sayson LV, Lee HJ, Ortiz DM, Kim BN, Kim HJ, Cheong JH
Communications biology 2021 Sep 20;4(1):1101
Communications biology 2021 Sep 20;4(1):1101
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of THRSP in extracts of various cell lines. Samples were incubated with THRSP polyclonal antibody (Product # PA5-77177).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of THRSP in U2OS cells. Samples were incubated with THRSP polyclonal antibody (Product # PA5-77177).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig. 1 The confirmation of mouse genotype and striatal THRSP levels. Before the start of each experiment, genotyping was conducted in 3-week-old mice using tail samples. a The THRSP OE mice show one band at 588 bp; in contrast, b the Hetero mice show two bands (568 and 503 bp), and KO mice show one band (568 bp). c Western blot using striatal tissue samples confirm the overexpression of THRSP protein levels in THRSP OE mice and the reduced expression in THRSP KO mice ( n = 6 mice/group; c one-way ANOVA, F (3,20) = 15.0, P < 0.001). Values are presented as the mean +- S.E.M. * P < 0.05, by one-way ANOVA with Bonferroni's multiple comparisons relative to WT.