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- References [2]
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- Product number
- NBP1-84715 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-84715, RRID:AB_11039048
- Product name
- Rabbit Polyclonal FBXW8 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human FBXW8 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.
Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?
Halbach MV, Stehning T, Damrath E, Jendrach M, Şen NE, Başak AN, Auburger G
PloS one 2015;10(3):e0121089
PloS one 2015;10(3):e0121089
Cullin 7 and Fbxw 8 expression in trophoblastic cells is regulated via oxygen tension: implications for intrauterine growth restriction?
Fahlbusch FB, Dawood Y, Hartner A, Menendez-Castro C, Nögel SC, Tzschoppe A, Schneider H, Strissel P, Beckmann MW, Schleussner E, Ruebner M, Dörr HG, Schild RL, Rascher W, Dötsch J
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2012 Nov;25(11):2209-15
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2012 Nov;25(11):2209-15
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FBXW8 Antibody [NBP1-84715] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FBXW8 Antibody [NBP1-84715] - Staining of human skeletal muscle shows low expression as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FBXW8 Antibody [NBP1-84715] - Staining in human thyroid gland and skeletal muscle tissues using anti-FBXW8 antibody. Corresponding FBXW8 RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: FBXW8 Antibody [NBP1-84715] - Staining of human thyroid gland shows high expression.
