Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [3]
- Immunocytochemistry [1]
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Validation data
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- Product number
- GTX100754 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX100754, RRID:AB_10618674
- Product name
- SNAI1 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references Upregulation of LGALS1 is associated with oral cancer metastasis.
The role of sentrin-specific protease 2 substrate recognition in TGF-β-induced tumorigenesis.
Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5.
Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis.
Lucidone Promotes the Cutaneous Wound Healing Process via Activation of the PI3K/AKT, Wnt/β-catenin and NF-κB Signaling Pathways.
Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells.
Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer.
The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.
NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial-mesenchymal transition.
Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma.
Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition.
TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways.
PGRMC1 contributes to doxorubicin-induced chemoresistance in MES-SA uterine sarcoma.
Li JM, Tseng CW, Lin CC, Law CH, Chien YA, Kuo WH, Chou HC, Wang WC, Chan HL
Therapeutic advances in medical oncology 2018;10:1758835918794622
Therapeutic advances in medical oncology 2018;10:1758835918794622
The role of sentrin-specific protease 2 substrate recognition in TGF-β-induced tumorigenesis.
Chang CC, Huang YS, Lin YM, Lin CJ, Jeng JC, Liu SM, Ho TL, Chang RT, Changou CA, Ho CC, Shih HM
Scientific reports 2018 Jun 28;8(1):9786
Scientific reports 2018 Jun 28;8(1):9786
Corylin Suppresses Hepatocellular Carcinoma Progression via the Inhibition of Epithelial-Mesenchymal Transition, Mediated by Long Noncoding RNA GAS5.
Chen CY, Chen CC, Shieh TM, Hsueh C, Wang SH, Leu YL, Lian JH, Wang TH
International journal of molecular sciences 2018 Jan 27;19(2)
International journal of molecular sciences 2018 Jan 27;19(2)
Employing an orthotopic model to study the role of epithelial-mesenchymal transition in bladder cancer metastasis.
Roth B, Jayaratna I, Sundi D, Cheng T, Melquist J, Choi W, Porten S, Nitti G, Navai N, Wszolek M, Guo C, Czerniak B, McConkey D, Dinney C
Oncotarget 2017 May 23;8(21):34205-34222
Oncotarget 2017 May 23;8(21):34205-34222
Lucidone Promotes the Cutaneous Wound Healing Process via Activation of the PI3K/AKT, Wnt/β-catenin and NF-κB Signaling Pathways.
Yang HL, Tsai YC, Korivi M, Chang CT, Hseu YC
Biochimica et biophysica acta. Molecular cell research 2017 Jan;1864(1):151-168
Biochimica et biophysica acta. Molecular cell research 2017 Jan;1864(1):151-168
Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells.
Liu YH, Weng YP, Lin HY, Tang SW, Chen CJ, Liang CJ, Ku CY, Lin JY
Scientific reports 2017 Jan 30;7:41437
Scientific reports 2017 Jan 30;7:41437
Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer.
Wang LT, Chiou SS, Chai CY, Hsi E, Chiang CM, Huang SK, Wang SN, Yokoyama KK, Hsu SH
Oncogene 2017 Aug;36(31):4405-4414
Oncogene 2017 Aug;36(31):4405-4414
The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways.
Chiu WC, Lee YC, Su YH, Wang YY, Tsai CH, Hou YA, Wang CH, Huang YF, Huang CJ, Chou SH, Hsieh PW, Yuan SF
PloS one 2016;11(11):e0166453
PloS one 2016;11(11):e0166453
NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial-mesenchymal transition.
Li HJ, Yu PN, Huang KY, Su HY, Hsiao TH, Chang CP, Yu MH, Lin YW
Oncogene 2016 Apr 28;35(17):2266-78
Oncogene 2016 Apr 28;35(17):2266-78
Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma.
Chen CY, Lin YS, Chen CL, Chao PZ, Chiou JF, Kuo CC, Lee FP, Lin YF, Sung YH, Lin YT, Li CF, Chen YJ, Chen CH
Oncotarget 2015 Sep 29;6(29):26946-59
Oncotarget 2015 Sep 29;6(29):26946-59
Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition.
Wang TH, Lin YS, Chen Y, Yeh CT, Huang YL, Hsieh TH, Shieh TM, Hsueh C, Chen TC
Oncotarget 2015 Sep 15;6(27):23342-57
Oncotarget 2015 Sep 15;6(27):23342-57
TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways.
Agliarulo I, Matassa DS, Amoroso MR, Maddalena F, Sisinni L, Sepe L, Ferrari MC, Arzeni D, Avolio R, Paolella G, Landriscina M, Esposito F
Biochimica et biophysica acta 2015 Oct;1853(10 Pt A):2570-9
Biochimica et biophysica acta 2015 Oct;1853(10 Pt A):2570-9
PGRMC1 contributes to doxorubicin-induced chemoresistance in MES-SA uterine sarcoma.
Lin ST, May EW, Chang JF, Hu RY, Wang LH, Chan HL
Cellular and molecular life sciences : CMLS 2015 Jun;72(12):2395-409
Cellular and molecular life sciences : CMLS 2015 Jun;72(12):2395-409
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- SNAI1 antibody detects SNAI1 protein by western blot analysis. Various whole cell extracts (30 ?g) were separated by 12% SDS-PAGE, and the membrane was blotted with SNAI1 antibody (GTX100754) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Untreated (¡V) and treated (+) HeLa whole cell extracts (30 ?g) were separated by 12% SDS-PAGE, and the membrane was blotted with SNAI1 antibody (GTX100754) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Untreated (¡V) and treated (+) HeLa whole cell extracts (50 ?g) were separated by 10% SDS-PAGE, and the membranes were blotted with SNAI1 antibody (GTX100754) diluted at 1:1000 and competitor's antibody (#3879) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.*The competitor is not affiliated with GeneTex and does not endorse this product.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- SNAI1 antibody detects SNAI1 protein at cytoplasm and nucleus by immunofluorescent analysis.Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: SNAI1 protein stained by SNAI1 antibody (GTX100754) diluted at 1:500.Blue: Hoechst 33342 staining.