CABT-B063

antibody from Creative Diagnostics
Targeting: EEF1A1 EE1A1, EEF1A, EF1A, LENG7
Provider product page for CABT-B063
Western blot

Antibody data

Product number
CABT-B063 - Provider product page
Provider
Creative Diagnostics
Product name
Anti-eEF1A polyclonal antibody
Antibody type
Polyclonal
Description
Elongation factors are proteins used in translation or protein synthesis during the process of cell cycle and elongation in some cells. In the ribosome, they facilitate translational elongation, from the formation of the first peptide bond to the formation of the last one. Specifically, elongation factor 1 alpha is the GTP-binding component of the eukaryotic elongation factor 1 complex (eEF1). In its active GTP-bound form, it binds to and delivers aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. The inactive GDP-bound form leaves the ribosome and must be recycled by its guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) before binding another molecule of aminoacyl-tRNA. eEF1A is required for nuclear export of aminoacyl-tRNAs, and may also be involved in translational quality control by targeting cotranslationally damaged proteins to the proteasome. eEF1A also exhibits actin filament-binding and -bundling activities and is involved in cytoskeleton organization.
Reactivity
Other
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Storage
4°C
EEF1A1 protein structure - CABT-B063 shown in red.