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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 11-7004-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-LSD1 Antibody
- Antibody type
- Polyclonal
- Description
- LSD1 or KDM1A (lysine (K)-specific demethylase 1A) gene encodes a nuclear protein which contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes. LSD1 or KDM1A is a demethylase that acts on both Lys 4 and 9 of histone H3. Consequently depending upon the use it may act as a co-activator or a co-repressor. It may have a role in the repression of neuronal genes. Two isoforms of LSD1 have been reported which are produced by alternative splicing. LSD1 has more or less ubiquitous expression.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant LSD1 p
rotein (amino acids 97-328) was use
d as the immunogen for this antibod
y.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of LSD1. Anti- LSD1 antibody (11-7004) was used at 0.5 µg/ml on 1) 293, 2) MCF-7 and 3) 3T3 lysates.
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of LSD1. Anti-LSD1 antibody (11-7004) in human Breast tissue at 5 µg/ml.
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of LSD1. Anti-LSD1 antibody (11-7004) in human Testis tissue at 5 µg/ml.
