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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- GTX114187 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX114187, RRID:AB_10619641
- Product name
- VDAC1 antibody [N1C2]
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
Submitted references Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species.
Glycyrrhizic acid induces human MDA-MB-231 breast cancer cell death and autophagy via the ROS-mitochondrial pathway.
The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells.
Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood.
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
Disruption of the human COQ5-containing protein complex is associated with diminished coenzyme Q10 levels under two different conditions of mitochondrial energy deficiency.
Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction.
Oxidative stress and the subcellular localization of the telomerase reverse transcriptase (TERT) in papillary thyroid cancer.
RRM2B-Mediated Regulation of Mitochondrial Activity and Inflammation under Oxidative Stress.
3,5-Diiodo-L-thyronine activates brown adipose tissue thermogenesis in hypothyroid rats.
Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients.
Changes in mitochondrial energy utilization in young and old worker honeybees (Apis mellifera).
Lee CW, Chi MC, Chang TM, Liu JF
Journal of cellular physiology 2019 Aug;234(8):13157-13168
Journal of cellular physiology 2019 Aug;234(8):13157-13168
Glycyrrhizic acid induces human MDA-MB-231 breast cancer cell death and autophagy via the ROS-mitochondrial pathway.
Lin SC, Chu PY, Liao WT, Wu MY, Tsui KH, Lin LT, Huang CH, Chen LL, Li CJ
Oncology reports 2018 Feb;39(2):703-710
Oncology reports 2018 Feb;39(2):703-710
The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells.
Valdez BC, Li Y, Murray D, Liu Y, Nieto Y, Champlin RE, Andersson BS
Leukemia & lymphoma 2017 Nov;58(11):2705-2716
Leukemia & lymphoma 2017 Nov;58(11):2705-2716
Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood.
Eguchi A, Lazaro RG, Wang J, Kim J, Povero D, Willliams B, Ho SB, Stärkel P, Schnabl B, Ohno-Machado L, Tsukamoto H, Feldstein AE
Hepatology (Baltimore, Md.) 2017 Feb;65(2):475-490
Hepatology (Baltimore, Md.) 2017 Feb;65(2):475-490
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
Chen X, Zhao X, Cai H, Sun H, Hu Y, Huang X, Kong W, Kong W
Redox biology 2017 Aug;12:987-1003
Redox biology 2017 Aug;12:987-1003
Disruption of the human COQ5-containing protein complex is associated with diminished coenzyme Q10 levels under two different conditions of mitochondrial energy deficiency.
Yen HC, Liu YC, Kan CC, Wei HJ, Lee SH, Wei YH, Feng YH, Chen CW, Huang CC
Biochimica et biophysica acta 2016 Sep;1860(9):1864-76
Biochimica et biophysica acta 2016 Sep;1860(9):1864-76
Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction.
Chiang MC, Cheng YC, Chen SJ, Yen CH, Huang RN
Experimental cell research 2016 Oct 1;347(2):322-31
Experimental cell research 2016 Oct 1;347(2):322-31
Oxidative stress and the subcellular localization of the telomerase reverse transcriptase (TERT) in papillary thyroid cancer.
Muzza M, Colombo C, Cirello V, Perrino M, Vicentini L, Fugazzola L
Molecular and cellular endocrinology 2016 Aug 15;431:54-61
Molecular and cellular endocrinology 2016 Aug 15;431:54-61
RRM2B-Mediated Regulation of Mitochondrial Activity and Inflammation under Oxidative Stress.
Cho EC, Kuo ML, Cheng JH, Cheng YC, Hsieh YC, Liu YR, Hsieh RH, Yen Y
Mediators of inflammation 2015;2015:287345
Mediators of inflammation 2015;2015:287345
3,5-Diiodo-L-thyronine activates brown adipose tissue thermogenesis in hypothyroid rats.
Lombardi A, Senese R, De Matteis R, Busiello RA, Cioffi F, Goglia F, Lanni A
PloS one 2015;10(2):e0116498
PloS one 2015;10(2):e0116498
Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients.
Cho EC, Kuo ML, Liu X, Yang L, Hsieh YC, Wang J, Cheng Y, Yen Y
Oncotarget 2014 Jul 15;5(13):4834-44
Oncotarget 2014 Jul 15;5(13):4834-44
Changes in mitochondrial energy utilization in young and old worker honeybees (Apis mellifera).
Chuang YL, Hsu CY
Age (Dordrecht, Netherlands) 2013 Oct;35(5):1867-79
Age (Dordrecht, Netherlands) 2013 Oct;35(5):1867-79
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ?g of whole cell lysate) A: A431 (GTX27909) 12% SDS PAGE VDAC1 antibody GTX114187 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using VDAC1(GTX114187) antibody at 1:500 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- VDAC1 antibody [N1C2] detects VDAC1 protein at mitochondria on mouse muscle by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. VDAC1 antibody [N1C2] (GTX114187) dilution: 1:500.
