Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB13012 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB13012, RRID:AB_10550028
- Product name
- BRCC3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BRCC3.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation.
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Chen X, Arciero CA, Wang C, Broccoli D, Godwin AK
Cancer research 2006 May 15;66(10):5039-46
Cancer research 2006 May 15;66(10):5039-46
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R
Molecular cell 2003 Nov;12(5):1087-99
Molecular cell 2003 Nov;12(5):1087-99
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BRCC3 in MCF-7 cell lysate with BRCC3 polyclonal antibody (Cat # PAB13012) at (A) 0.5, (B) 1 and (C) 2 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of BRCC3 in human brain tissue with BRCC3 polyclonal antibody (Cat # PAB13012) at 2.5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)