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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- MAB7555 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB7555, RRID:AB_10678078
- Product name
- BRCC3 monoclonal antibody, clone AT3B1
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against recombinant BRCC3.
- Isotype
- IgG
- Antibody clone number
- AT3B1
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.
BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation.
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Wang B, Elledge SJ
Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 26;104(52):20759-63
Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 26;104(52):20759-63
BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation.
Chen X, Arciero CA, Wang C, Broccoli D, Godwin AK
Cancer research 2006 May 15;66(10):5039-46
Cancer research 2006 May 15;66(10):5039-46
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R
Molecular cell 2003 Nov;12(5):1087-99
Molecular cell 2003 Nov;12(5):1087-99
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- Abnova Corporation (provider)
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- Experimental details
- Cell lysates of HeLa (20 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with BRCC3 monoclonal antibody, clone AT3B1 (Cat # MAB7555) (1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
