Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- ABIN400864 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316), (N-Term) antibody
- Antibody type
- Monoclonal
- Description
- Protein-G affinity chromatography
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-316, N-Term
- Isotype
- IgG
- Antibody clone number
- AT3B1
- Vial size
- 0.1 mL
- Storage
- Store the antibody undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°Cfor longer. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Submitted references Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.
BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation.
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Wang B, Elledge SJ
Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 26;104(52):20759-63
Proceedings of the National Academy of Sciences of the United States of America 2007 Dec 26;104(52):20759-63
BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation.
Chen X, Arciero CA, Wang C, Broccoli D, Godwin AK
Cancer research 2006 May 15;66(10):5039-46
Cancer research 2006 May 15;66(10):5039-46
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R
Molecular cell 2003 Nov;12(5):1087-99
Molecular cell 2003 Nov;12(5):1087-99
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Supportive validation
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- WB
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- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC