Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 24103-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#24103-1-AP, RRID:AB_2737369
- Product name
- PCGF6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PCGF6 antibody (Cat. #24103-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
E2F6 initiates stable epigenetic silencing of germline genes during embryonic development.
Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.
SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States.
MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6.
Stielow B, Zhou Y, Cao Y, Simon C, Pogoda HM, Jiang J, Ren Y, Phanor SK, Rohner I, Nist A, Stiewe T, Hammerschmidt M, Shi Y, Bulyk ML, Wang Z, Liefke R
Science advances 2021 May;7(20)
Science advances 2021 May;7(20)
E2F6 initiates stable epigenetic silencing of germline genes during embryonic development.
Dahlet T, Truss M, Frede U, Al Adhami H, Bardet AF, Dumas M, Vallet J, Chicher J, Hammann P, Kottnik S, Hansen P, Luz U, Alvarez G, Auclair G, Hecht J, Robinson PN, Hagemeier C, Weber M
Nature communications 2021 Jun 11;12(1):3582
Nature communications 2021 Jun 11;12(1):3582
Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.
Mathsyaraja H, Catchpole J, Freie B, Eastwood E, Babaeva E, Geuenich M, Cheng PF, Ayers J, Yu M, Wu N, Moorthi S, Poudel KR, Koehne A, Grady W, Houghton AM, Berger AH, Shiio Y, MacPherson D, Eisenman RN
eLife 2021 Jul 8;10
eLife 2021 Jul 8;10
SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States.
Cossec JC, Theurillat I, Chica C, Búa Aguín S, Gaume X, Andrieux A, Iturbide A, Jouvion G, Li H, Bossis G, Seeler JS, Torres-Padilla ME, Dejean A
Cell stem cell 2018 Nov 1;23(5):742-757.e8
Cell stem cell 2018 Nov 1;23(5):742-757.e8
MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6.
Stielow B, Finkernagel F, Stiewe T, Nist A, Suske G
PLoS genetics 2018 Jan;14(1):e1007193
PLoS genetics 2018 Jan;14(1):e1007193
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The PCGF6 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PCGF6. This antibody recognizes human antigen. The PCGF6 antibody has been validated for the following applications: ELISA, WB analysis.