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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 13534-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13534-1-AP, RRID:AB_2236528
- Product name
- P2RX4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated P2RX4 antibody (Cat. #13534-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Chitosan biomaterial enhances the effect of OECs on the inhibition of sciatic nerve injury-induced neuropathic pain.
Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy.
Analgesic effect of nobiletinĀ against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
P2X4 Inhibition reduces microglia inflammation and apoptosis by NLRP3 and improves nervous system defects in rat brain trauma model.
Ī±-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling.
Activation of P2X4 receptor exacerbates acute brain injury after intracerebral hemorrhage.
An Inflammatory Response-Related Gene Signature Can Impact the Immune Status and Predict the Prognosis of Hepatocellular Carcinoma.
Electroacupuncture effects on the P2X4R pathway in microglia regulating the excitability of neurons in the substantia gelatinosa region of rats with spinal nerve ligation.
Neuroprotective and neuro-rehabilitative effects of acute purinergic receptor P2X4 (P2X4R) blockade after ischemic stroke.
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.
Lysophosphatidic acid precursor levels decrease and an arachidonic acid-containing phosphatidylcholine level increases in the dorsal root ganglion of mice after peripheral nerve injury.
Hu JL, Luo HL, Liu JP, Zuo C, Xu YS, Feng X, Zhang WJ
Journal of chemical neuroanatomy 2023 Nov;133:102327
Journal of chemical neuroanatomy 2023 Nov;133:102327
Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy.
Wang K, Fu S, Dong L, Zhang D, Wang M, Wu X, Shen E, Luo L, Li C, Nice EC, Huang C, Zou B
Autophagy 2023 Dec;19(12):3132-3150
Autophagy 2023 Dec;19(12):3132-3150
Analgesic effect of nobiletinĀ against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhu C, Tian M, Liu N, Ma L, Lan X, Yang J, Du J, Ma H, Li Y, Zheng P, Yu J, Peng X
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
P2X4 Inhibition reduces microglia inflammation and apoptosis by NLRP3 and improves nervous system defects in rat brain trauma model.
He W, Wang Q, Sha W, Wang L, Li D, Chen G
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2022 May;99:224-232
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2022 May;99:224-232
Ī±-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling.
Yuan Y, Zhu C, Wang Y, Sun J, Feng J, Ma Z, Li P, Peng W, Yin C, Xu G, Xu P, Jiang Y, Jiang Q, Shu G
Science advances 2022 May 6;8(18):eabn2879
Science advances 2022 May 6;8(18):eabn2879
Activation of P2X4 receptor exacerbates acute brain injury after intracerebral hemorrhage.
Wu ST, Han JR, Yao N, Li YL, Zhang F, Shi Y, Shi FD, Li ZG
CNS neuroscience & therapeutics 2022 Jul;28(7):1008-1018
CNS neuroscience & therapeutics 2022 Jul;28(7):1008-1018
An Inflammatory Response-Related Gene Signature Can Impact the Immune Status and Predict the Prognosis of Hepatocellular Carcinoma.
Lin Z, Xu Q, Miao D, Yu F
Frontiers in oncology 2021;11:644416
Frontiers in oncology 2021;11:644416
Electroacupuncture effects on the P2X4R pathway in microglia regulating the excitability of neurons in the substantia gelatinosa region of rats with spinal nerve ligation.
Zheng Y, Jia C, Jiang X, Chen J, Chen XL, Ying X, Wu J, Jiang M, Yang G, Tu W, Zhou K, Jiang S
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Neuroprotective and neuro-rehabilitative effects of acute purinergic receptor P2X4 (P2X4R) blockade after ischemic stroke.
Srivastava P, Cronin CG, Scranton VL, Jacobson KA, Liang BT, Verma R
Experimental neurology 2020 Jul;329:113308
Experimental neurology 2020 Jul;329:113308
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.
Long T, He W, Pan Q, Zhang S, Zhang D, Qin G, Chen L, Zhou J
The journal of headache and pain 2020 Jan 14;21(1):4
The journal of headache and pain 2020 Jan 14;21(1):4
Lysophosphatidic acid precursor levels decrease and an arachidonic acid-containing phosphatidylcholine level increases in the dorsal root ganglion of mice after peripheral nerve injury.
Mihara Y, Horikawa M, Sato S, Eto F, Hanada M, Banno T, Arima H, Ushirozako H, Yamada T, Xu D, Okamoto A, Yamazaki F, Takei S, Omura T, Yao I, Matsuyama Y, Setou M
Neuroscience letters 2019 Apr 17;698:69-75
Neuroscience letters 2019 Apr 17;698:69-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 13534-1-AP(P2RX4 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 13534-1-AP(P2RX4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 13534-1-AP(P2RX4 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The P2RX4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human P2RX4. This antibody recognizes human,mouse,rat antigen. The P2RX4 antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
