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- Antibody Data
- Antigen structure
- References [621]
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- Western blot [2]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 11224-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11224-1-AP, RRID:AB_2210206
- Product name
- alpha Tubulin antibody
- Antibody type
- Polyclonal
- Description
- Alpha Tubulin antibody (Cat. #11224-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Butyrate ameliorates skeletal muscle atrophy in diabetic nephropathy by enhancing gut barrier function and FFA2-mediated PI3K/Akt/mTOR signals.
Virus-induced FoxO factor facilitates replication of human cytomegalovirus.
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
αTAT1-induced tubulin acetylation promotes ameloblastoma migration and invasion.
Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2+ diffuse large B-cell lymphomas.
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
High PHD Finger Protein 19 (PHF19) expression predicts poor prognosis in colorectal cancer: a retrospective study.
Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure.
MicroRNA-222 Transferred From Semen Extracellular Vesicles Inhibits Sperm Apoptosis by Targeting BCL2L11.
Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway.
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
RBM14 Modulates Tubulin Acetylation and Regulates Spindle Morphology During Meiotic Maturation in Mouse Oocytes.
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Network-Based Expression Analyses and Experimental Verifications Reveal the Involvement of STUB1 in Acute Kidney Injury.
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
Brusatol Inhibits Tumor Growth and Increases the Efficacy of Cabergoline against Pituitary Adenomas.
Glucagon-like Peptide-1 Improves Fatty Liver and Enhances Thermogenesis in Brown Adipose Tissue via Inhibiting BMP4-Related Signaling Pathway in High-Fat-Diet-Induced Obese Mice.
USP1 Promotes GC Metastasis via Stabilizing ID2.
Generation of VEGF knock-in Cashmere goat via the CRISPR/Cas9 system.
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis.
STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2.
Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting.
Identification of a Novel Epigenetic Signature CHFR as a Potential Prognostic Gene Involved in Metastatic Clear Cell Renal Cell Carcinoma.
Effect of Xanthium Strumarium on HIV-1 5'-LTR Transcriptional Activity and Viral Reactivation in Latently Infected Cells.
Activation of STING Pathway Contributed to Cisplatin-Induced Cardiac Dysfunction via Promoting the Activation of TNF-α-AP-1 Signal Pathway.
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway.
Potential Role of SWI/SNF Complex Subunit Actin-Like Protein 6A in Cervical Cancer.
Periodontal Pathogens Promote Oral Squamous Cell Carcinoma by Regulating ATR and NLRP3 Inflammasome.
Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Identification METTL18 as a Potential Prognosis Biomarker and Associated With Immune Infiltrates in Hepatocellular Carcinoma.
Targeting Mutated p53 Dependency in Triple-Negative Breast Cancer Cells Through CDK7 Inhibition.
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
Salmonella Effector SpvB Inhibits NF-κB Activity via KEAP1-Mediated Downregulation of IKKβ.
Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis.
Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of sirtuin 1.
Inhibitory effect of HTLV-1 infection on the production of B-cell activating factors in established follicular dendritic cell-like cells.
Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder.
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
The inhibitory effect of the deubiquitinase cylindromatosis (CYLD) on inflammatory responses in human gingival fibroblasts.
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
PEX5 prevents cardiomyocyte hypertrophy via suppressing the redox-sensitive signaling pathways MAPKs and STAT3.
Matrine injection inhibits pancreatic cancer growth via modulating carbonic anhydrases- a network pharmacology-based study with in vitro validation.
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling.
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome.
The protective effect of isoflurane pretreatment on liver IRI by suppressing noncanonical pyroptosis of liver macrophages.
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Assembly of Cytoplasmic Stress Granules in Placentas in Women with Preeclampsia.
Oxidized phospholipids on alkyl-amide scaffold demonstrate anti-endotoxin and endothelial barrier-protective properties.
Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases.
Deacetylation of BmAda3 is required for cell apoptosis caused by Bombyx mori nucleopolyhedrovirus infection.
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment.
Folic Acid-Appended Hydroxypropyl-β-Cyclodextrin Exhibits Potent Antitumor Activity in Chronic Myeloid Leukemia Cells via Autophagic Cell Death.
19-Hydroxybufalin inhibits non-small cell lung cancer cell proliferation and promotes cell apoptosis via the Wnt/β-catenin pathway.
CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis.
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Bortezomib potentiates antitumor activity of mitoxantrone through dampening Wnt/β-catenin signal pathway in prostate cancer cells.
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation.
FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination.
Effects and Mechanisms of Synaptotagmin-7 in the Hippocampus on Cognitive Impairment in Aging Mice.
C23 gene regulates the nucleolin structure and biosynthesis of ribosomes in bovine intraspecific and interspecific somatic cell nuclear transfer embryos.
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
WIPI-1 inhibits metastasis and tumour growth via the WIPI-1-TRIM21 axis and MYC regulation in nasopharyngeal carcinoma.
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
LncRNA Riken Attenuated Sevoflurane-Induced Neuroinflammation by Regulating the MicroRNA-101a/MKP-1/JNK Pathway.
The Acetylation Modification of SP1 Regulates the Protein Stability in Silkworm.
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
The deubiquitinating enzyme ATXN3 promotes the progression of anaplastic thyroid carcinoma by stabilizing EIF5A2.
TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration.
W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319.
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage.
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Role of epigenetic m6 A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR-AKT signaling.
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
Nicotine-derived NNK induces the stemness enrichment of CRC cells through regulating the balance of DUSP4-ERK1/2 feedback loop.
mTOR regulates PRMT1 expression and mitochondrial mass through STAT1 phosphorylation in hepatic cell.
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Pathogenesis of acephalic spermatozoa syndrome caused by SUN5 variant.
Ggps1 deficiency in the uterus results in dystocia by disrupting uterine contraction.
Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma.
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer.
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Genistein suppresses allergic contact dermatitis through regulating the MAP2K2/ERK pathway.
HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.
H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes.
Butyrate alleviates PTZ-induced mitochondrial dysfunction, oxidative stress and neuron apoptosis in mice via Keap1/Nrf2/HO-1 pathway.
Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics.
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
USP34 regulates tooth root morphogenesis by stabilizing NFIC.
Endometrial cell-derived small extracellular vesicle miR-100-5p promotes functions of trophoblast during embryo implantation.
Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN.
HN1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by interacting with STMN1.
SIRT1 inhibitors mitigate radiation-induced GI syndrome by enhancing intestinal-stem-cell survival.
Selenite Inhibits Notch Signaling in Cells and Mice.
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Hypoxic training upregulates mitochondrial turnover and angiogenesis of skeletal muscle in mice.
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Tanshinone IIA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehydrogenase in macrophages.
Protective effects of total flavonoids from Qu Zhi Qiao (fruit of Citrus paradisi cv. Changshanhuyou) on OVA-induced allergic airway inflammation and remodeling through MAPKs and Smad2/3 signaling pathway.
Treg deficiency-mediated TH 1 response causes human premature ovarian insufficiency through apoptosis and steroidogenesis dysfunction of granulosa cells.
Immunoprecipitation Strategies to Isolate RIPK1/RIPK3 Complexes in Mouse Macrophages.
A human β-casein-derived peptide BCCY-1 modulates the innate immune response.
Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.
DNA methylation mediated RSPO2 to promote follicular development in mammals.
High expression of aryl hydrocarbon receptor (AhR) plays an important role in the formation of fibrous epulis.
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes.
Engorgement of Rhipicephalus haemaphysaloides ticks blocked by silencing a protein inhibitor of apoptosis.
Apoptotic caspases suppress Mycobacterium bovis-induced IFN-β production in murine macrophage.
Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin.
Reconsolidation of a post-ingestive nutrient memory requires mTOR in the central amygdala.
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
PKD2 deficiency suppresses amino acid biosynthesis in ADPKD by impairing the PERK-TBL2-eIF2ɑ-ATF4 pathway.
Planar cell polarity induces local microtubule bundling for coordinated ciliary beating.
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Time-dependent expression of ryanodine receptors in sea urchin eggs, zygotes and early embryos.
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation.
Actin-granule formation is an additional step in cardiac myofibroblast differentiation.
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.
The inhibition of colorectal cancer growth by the natural product macrocarpal I.
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Silencing integrin α6 enhances the pluripotency-differentiation transition in human dental pulp stem cells.
Skip participates in formation and lipid metabolism of beige adipose and might mediate the effects of SIRT1 activator BTM-0512 on beige remodeling.
CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9.
Exosomes derived from thymic stromal lymphopoietin-treated dendritic cells regulate T helper 17/regulatory T cell differentiation via miR-21/Smad7 axis.
Changes in the expression of endothelial monocyte‑activating polypeptide II in the rat hippocampus following status epilepticus.
METTL3-Mediated m6 A mRNA Methylation Modulates Tooth Root Formation by Affecting NFIC Translation.
Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer.
Targeting ROCK1/2 blocks cell division and induces mitotic catastrophe in hepatocellular carcinoma.
Knockdown of ASH1L methyltransferase induced apoptosis inhibiting proliferation and H3K36 methylation in bovine cumulus cells.
Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer's disease.
Integrated analysis of microRNA and mRNA expression profiling identifies BAIAP3 as a novel target of dysregulated hsa-miR-1972 in age-related white matter lesions.
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy.
Aberrantly high activation of a FoxM1-STMN1 axis contributes to progression and tumorigenesis in FoxM1-driven cancers.
Semaphorin 3A promotes the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells in inflammatory environments by suppressing the Wnt/β-catenin signaling pathway.
Histone Deacetylase Inhibitor SAHA Induces Expression of Fatty Acid-Binding Protein 4 and Inhibits Replication of Human Cytomegalovirus.
Small molecule targeting topoisomerase 3β for cancer therapy.
Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells.
Effects and mechanisms of probucol on aging-related hippocampus-dependent cognitive impairment.
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.
GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity.
ZNRF2 attenuates focal cerebral ischemia/reperfusion injury in rats by inhibiting mTORC1-mediated autophagy.
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target.
Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage.
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin.
Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse.
CBL aggravates Ang II-induced cardiac hypertrophy via the VHL/HIF-1α pathway.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Adenosine A3 receptor activated in H2O2 oxidative stress of primary open-angle glaucoma.
Triterpene saponins from Guo-gang-long attenuate collagen-induced arthritis via regulating A20 and inhibiting MAPK pathway.
Human splenic TER cells: A relevant prognostic factor acting via the artemin-GFRα3-ERK pathway in pancreatic ductal adenocarcinoma.
Dnajb8, a target gene of SOX30, is dispensable for male fertility in mice.
ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs.
An MRTF-A-Sp1-PDE5 Axis Mediates Angiotensin-II-Induced Cardiomyocyte Hypertrophy.
Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.
PCDH7 Inhibits the Formation of Homotypic Cell-in-Cell Structure.
RGS12 is required for the maintenance of mitochondrial function during skeletal development.
Glutamine protects intestine against ischemia-reperfusion injury by alleviating endoplasmic reticulum stress induced apoptosis in rats.
Ambroxol Improves Neuronal Survival and Reduces White Matter Damage through Suppressing Endoplasmic Reticulum Stress in Microglia after Intracerebral Hemorrhage.
Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation.
MicroRNA-384 Inhibits the Progression of Papillary Thyroid Cancer by Targeting PRKACB.
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Wnt5a/CaMKII/ERK/CCL2 axis is required for tumor-associated macrophages to promote colorectal cancer progression.
MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor.
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Kaempferol attenuated cisplatin-induced cardiac injury via inhibiting STING/NF-κB-mediated inflammation.
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway.
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma.
Phosphoribosyl pyrophosphate synthetases 2 knockdown inhibits prostate cancer progression by suppressing cell cycle and inducing cell apoptosis.
Overexpression of KIAA0101 Promotes the Progression of Non-small Cell Lung Cancer.
Inward Tension of Talin and Integrin-related Osmotic Pressure are involved Synergetically in the Invasion and Metastasis of Non-small Cell Lung Cancer.
High-Intensity Interval Training Restores Glycolipid Metabolism and Mitochondrial Function in Skeletal Muscle of Mice With Type 2 Diabetes.
Coxsackievirus A6 Induces Necroptosis for Viral Production.
Establishment of cell lines with porcine spermatogonial stem cell properties.
Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription.
SYTL4 downregulates microtubule stability and confers paclitaxel resistance in triple-negative breast cancer.
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
A Prognostic Prediction Model Developed Based on Four CpG Sites and Weighted Correlation Network Analysis Identified DNAJB1 as a Novel Biomarker for Pancreatic Cancer.
SYPL1 Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma via Suppression of ROS-Induced ERK Activation.
Caspase-3 inhibitor inhibits enterovirus D68 production.
The chromatin remodeler Brg1 is required for formation and maintenance of hematopoietic stem cells.
Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.
Dependence of PINK1 accumulation on mitochondrial redox system.
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Comprehensive lipidomics in apoM-/- mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation.
Metformin improves boar sperm quality via 5'-AMP-activated protein kinase-mediated energy metabolism in vitro.
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Consumption of a Blueberry-Enriched Diet by Women for 6 Weeks Alters Determinants of Human Muscle Progenitor Cell Function.
Proline Protects Boar Sperm against Oxidative Stress through Proline Dehydrogenase-Mediated Metabolism and the Amine Structure of Pyrrolidine.
NQO1-selective activated prodrugs of combretastatin A-4: Synthesis and biological evaluation.
SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation.
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Broad-complex transcription factor mediates opposing hormonal regulation of two phylogenetically distant arginine kinase genes in Tribolium castaneum.
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level.
HOXA13 promotes colon cancer progression through β-catenin-dependent WNT pathway.
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells.
Anti-inflammatory and analgesic activities of indigo through regulating the IKKβ/IκB/NF-κB pathway in mice.
Atractyloside targets cancer-associated fibroblasts and inhibits the metastasis of colon cancer.
Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status.
Elevated miR-124-3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T-synthase.
Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.
Melatonin Rescues the Ti Particle-Impaired Osteogenic Potential of Bone Marrow Mesenchymal Stem Cells via the SIRT1/SOD2 Signaling Pathway.
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury.
Cell Signaling Coordinates Global PRC2 Recruitment and Developmental Gene Expression in Murine Embryonic Stem Cells.
The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs.
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca2+/CaMKII/CREB signaling pathway.
MKL1 mediates TGF-β-induced CTGF transcription to promote renal fibrosis.
Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin.
The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair.
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
GDF15 knockdown promotes erastin-induced ferroptosis by decreasing SLC7A11 expression.
Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia.
Second-order optimized regularized structured illumination microscopy (sorSIM) for high-quality and rapid super resolution image reconstruction with low signal level.
Autophagy suppression of trophoblast cells induces pregnancy loss by activating decidual NK cytotoxicity and inhibiting trophoblast invasion.
PIM1 inhibitor synergizes the anti-tumor effect of osimertinib via STAT3 dephosphorylation in EGFR-mutant non-small cell lung cancer.
Ophiopogonin D promotes bone regeneration by stimulating CD31hi EMCNhi vessel formation.
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Inhibition of UCHL1 by LDN-57444 attenuates Ang II-Induced atrial fibrillation in mice.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCFβ-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer.
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development.
MACF1 promotes preosteoblast migration by mediating focal adhesion turnover through EB1.
Dietary Supplemented Curcumin Improves Meat Quality and Antioxidant Status of Intrauterine Growth Retardation Growing Pigs via Nrf2 Signal Pathway.
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
AFF1 inhibits adipogenic differentiation via targeting TGM2 transcription.
Proanthocyanidins Promote Osteogenic Differentiation of Human Periodontal Ligament Fibroblasts in Inflammatory Environment Via Suppressing NF-κB Signal Pathway.
Transient inhibition of rDNA transcription in donor cells improves ribosome biogenesis and preimplantation development of embryos derived from somatic cell nuclear transfer.
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
Ophiocordyceps lanpingensis polysaccharides attenuate pulmonary fibrosis in mice.
Downregulated miR-150 in bone marrow mesenchymal stem cells attenuates the apoptosis of LPS-stimulated RAW264.7 via MTCH2-dependent mitochondria transfer.
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis.
Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages.
Fine particulate matter increases airway hyperresponsiveness through kallikrein-bradykinin pathway.
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis.
Expression and significance of T-cell immunoglobulin mucin molecule 3 and its ligand galectin-9 in patients with adenomyosis.
EHF promotes colorectal carcinoma progression by activating TGF-β1 transcription and canonical TGF-β signaling.
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation.
Clinically relevant high levels of human C-reactive protein induces endothelial dysfunction and hypertension by inhibiting the AMPK-eNOS axis.
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Downregulation of the circadian rhythm regulator HLF promotes multiple-organ distant metastases in non-small cell lung cancer through PPAR/NF-κb signaling.
Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation.
Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Poly (ADP-ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation-associated chemotherapy-induced autophagy in leukaemia cells.
Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition.
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.
MicroRNA-547-5p-mediated interleukin-33/suppressor of tumorigenicity 2 signaling underlies the genesis and maintenance of neuropathic pain and is targeted by the therapy with bone marrow stromal cells.
CXCL12/CXCR4 signaling induced itch and pain sensation in a murine model of allergic contact dermatitis.
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
The Capsid Protein of Semliki Forest Virus Antagonizes RNA Interference in Mammalian Cells.
Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.
Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
ING4 alleviated lipopolysaccharide-induced inflammation by regulating the NF-κB pathway via a direct interaction with SIRT1.
Biallelic mutation of HSD17B4 induces middle age-onset spinocerebellar ataxia.
Functional analysis of natural PCSK9 mutants in modern and archaic humans.
Expanding the retinal phenotype of RP1: from retinitis pigmentosa to a novel and singular macular dystrophy.
The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets.
Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).
Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.
WDR62 is a novel participator in spindle migration and asymmetric cytokinesis during mouse oocyte meiotic maturation.
Bnip3 mediates doxorubicin-induced cardiomyocyte pyroptosis via caspase-3/GSDME.
Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation.
Asiaticoside Inhibits Neuronal Apoptosis and Promotes Functional Recovery After Spinal Cord Injury in Rats.
Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol transport.
ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin-3 and NRXN3.
Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists.
EBV-miR-BART12 accelerates migration and invasion in EBV-associated cancer cells by targeting tubulin polymerization-promoting protein 1.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Macrophage-stimulating activity of European eel (Anguilla anguilla) peptides in RAW264.7 cells mediated via NF-κB and MAPK signaling pathways.
Naked antisense double-stranded DNA oligonucleotide efficiently suppresses BCR-ABL positive leukemic cells.
Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress.
Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer.
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease.
Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.
Mechanical Ring Interfaces between Adherens Junction and Contractile Actomyosin to Coordinate Entotic Cell-in-Cell Formation.
Regulation of Female Folliculogenesis by Tsp1a in Nile Tilapia (Oreochromis niloticus).
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down-regulating CCNE2 in pancreatic ductal adenocarcinoma.
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Alternatively Polarized Macrophages Regulate the Growth and Differentiation of Ependymal Stem Cells through the SIRT2 Pathway.
SIRT6-PARP1 is involved in HMGB1 polyADP-ribosylation and acetylation and promotes chemotherapy-induced autophagy in leukemia.
Hepatic CD147 knockout modulates liver steatosis and up-regulates autophagy in high-fat-diet-induced NAFLD mice.
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma.
Ovarian cancer cell-secreted exosomal miR-205 promotes metastasis by inducing angiogenesis.
Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma.
Identification of Aloperine as an anti-apoptotic Bcl2 protein inhibitor in glioma cells.
Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction.
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury.
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells.
Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis.
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation.
Histone Demethylase UTX is an Essential Factor for Zygotic Genome Activation and Regulates Zscan4 Expression in Mouse Embryos.
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells.
Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway.
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway.
Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction.
Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway.
Qingpeng Ointment Ameliorates Inflammatory Responses and Dysregulation of Itch-Related Molecules for Its Antipruritic Effects in Experimental Allergic Contact Dermatitis.
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.
Functional role of GKAP1 in the regulation of male germ cell spontaneous apoptosis and sperm number.
miR-125b-5p targeting TRAF6 relieves skeletal muscle atrophy induced by fasting or denervation.
Calcium channel blockers reduce severe fever with thrombocytopenia syndrome virus (SFTSV) related fatality.
Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells.
Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin.
Proteomics Profiling of Host Cell Response via Protein Expression and Phosphorylation upon Dengue Virus Infection.
In situ repurposing of dendritic cells with CRISPR/Cas9-based nanomedicine to induce transplant tolerance.
TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production.
CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells.
NEDD4 protects vascular endothelial cells against Angiotensin II-induced cell death via enhancement of XPO1-mediated nuclear export.
The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosis.
Endoplasmic reticulum stress, a novel significant mechanism responsible for DEHP-induced increased distance between seminiferous tubule of mouse testis.
Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2.
MicroRNA-125a-3p affects smooth muscle cell function in vascular stenosis.
ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma.
Bioinformatics Analysis Identifies Protein Tyrosine Kinase 7 (PTK7) as a Potential Prognostic and Therapeutic Biomarker in Stages I to IV Hepatocellular Carcinoma.
Mitochondrial pyruvate carrier 2 mediates mitochondrial dysfunction and apoptosis in high glucose-treated podocytes.
Enhancement of cortisol-induced SAA1 transcription by SAA1 in the human amnion.
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation.
Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels.
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
PTK2 promotes cancer stem cell traits in hepatocellular carcinoma by activating Wnt/β-catenin signaling.
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.
NFAT1 Hypermethylation Promotes Epithelial-Mesenchymal Transition and Metastasis in Nasopharyngeal Carcinoma by Activating ITGA6 Transcription.
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress.
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte.
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.
The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs.
Dendrobium officinale polysaccharides regulate age-related lineage commitment between osteogenic and adipogenic differentiation.
Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning.
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
NPRL2 enhances autophagy and the resistance to Everolimus in castration-resistant prostate cancer.
FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma.
The pivotal role of protein acetylation in linking glucose and fatty acid metabolism to β-cell function.
HOXA9 is a novel myopia risk gene.
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
CD147 promotes progression of head and neck squamous cell carcinoma via NF-kappa B signaling.
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness.
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer.
Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A3 Adenosine Receptor.
Small GTPase Arf6 regulates diabetes-induced cholesterol accumulation in podocytes.
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line.
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases.
Targeting CDK12-mediated transcription regulation in anaplastic thyroid carcinoma.
Involvement of STAT3 in the synergistic induction of 11β-HSD1 by SAA1 and cortisol in human amnion fibroblasts.
Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction.
The Mechanism of Rap1 Regulates N-cadherin to Control Neuronal Migration.
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation.
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
Krüppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome.
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-κB signaling pathway.
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells.
The Novel Nature Microtubule Inhibitor Ivalin Induces G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells In Vitro.
Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation.
Altered expression of p63 isoforms and expansion of p63- and club cell secretory protein-positive epithelial cells in the lung as novel features of aging.
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection.
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Fas Signaling in Dendritic Cells Mediates Th2 Polarization in HDM-Induced Allergic Pulmonary Inflammation.
TRIM31 Deficiency Is Associated with Impaired Glucose Metabolism and Disrupted Gut Microbiota in Mice.
Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6.
Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway.
Resveratrol-Induced Downregulation of NAF-1 Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine via the ROS/Nrf2 Signaling Pathways.
MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3.
XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer.
Liver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma.
The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation.
The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Oocyte-specific deletion of Gsα induces oxidative stress and deteriorates oocyte quality in mice.
XPO1-mediated nuclear export of RNF146 protects from angiotensin II-induced endothelial cellular injury.
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
β-catenin regulates IRF3-mediated innate immune signalling in colorectal cancer.
Inhibitor of apoptosis protein‑like protein‑2: A novel growth accelerator for breast cancer cells.
Low-density lipoprotein receptor-related protein 6 regulates alternative pre-mRNA splicing.
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Administration of ubiquitin-activating enzyme UBA1 inhibitor PYR-41 attenuates angiotensin II-induced cardiac remodeling in mice.
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.
Nucleoporin35 is a novel microtubule associated protein functioning in oocyte meiotic spindle architecture.
Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent.
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure.
Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways.
HSF4 transcriptional regulates HMOX-1 expression in HLECs.
Targeting LC3 and Beclin-1 autophagy genes suppresses proliferation, survival, migration and invasion by inhibition of Cyclin-D1 and uPAR/Integrin β1/ Src signaling in triple negative breast cancer cells.
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
High expression of NPRL2 is linked to poor prognosis in patients with prostate cancer.
Sofosbuvir inhibits hepatitis A virus replication in vitro assessed by a cell-based fluorescent reporter system.
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.
HuR regulates telomerase activity through TERC methylation.
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis.
Epigenetic activation of PERP transcription by MKL1 contributes to ROS-induced apoptosis in skeletal muscle cells.
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.
Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation.
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage.
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Novel RAS Inhibitors Poricoic Acid ZG and Poricoic Acid ZH Attenuate Renal Fibrosis via a Wnt/β-Catenin Pathway and Targeted Phosphorylation of smad3 Signaling.
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells.
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
Hypothalamic DNA methylation in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture.
TUSC3 accelerates cancer growth and induces epithelial-mesenchymal transition by upregulating claudin-1 in non-small-cell lung cancer cells.
Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation.
Aging-dependent decrease in the numbers of enteric neurons, interstitial cells of Cajal and expression of connexin43 in various regions of gastrointestinal tract.
Expression profiling identified IL-8 as a regulator of homotypic cell-in-cell formation.
Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells.
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.
Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53.
Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6.
Hydrogen sulfide generation from l-cysteine in the human glioblastoma-astrocytoma U-87 MG and neuroblastoma SHSY5Y cell lines.
HMGB1 binding heptamer peptide improves survival and ameliorates brain injury in rats after cardiac arrest and cardiopulmonary resuscitation.
FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Palladin is a novel microtubule-associated protein responsible for spindle orientation.
Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice.
PKC θ-mediated Ca2+/NF-AT signalling pathway may be involved in T-cell immunosuppression in coal-burning arsenic-poisoned population.
Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.
NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit.
HIF-1α coordinates epigenetic activation of SIAH1 in hepatocytes in response to nutritional stress.
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase.
Inhibition of IL-8-mediated endothelial adhesion, VSMCs proliferation and migration by siRNA-TMEM98 suggests TMEM98's emerging role in atherosclerosis.
Regulation of m6A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.
Downregulation of NAD-Dependent Deacetylase SIRT2 Protects Mouse Brain Against Ischemic Stroke.
Analysis of gene expression and functional characterization of XPR1: a pathogenic gene for primary familial brain calcification.
BRAFV600E and RET/PTC Promote Proliferation and Migration of Papillary Thyroid Carcinoma Cells In Vitro by Regulating Nuclear Factor-κB.
Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma.
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
MicroRNA let-7g possesses a therapeutic potential for peripheral artery disease.
PTPIP51 regulates mouse cardiac ischemia/reperfusion through mediating the mitochondria-SR junction.
Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway.
JOSD1 Negatively Regulates Type-I Interferon Antiviral Activity by Deubiquitinating and Stabilizing SOCS1.
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.
Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.
Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening.
Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells.
Anthocyanins from Black Chokeberry (Aroniamelanocarpa Elliot) Delayed Aging-Related Degenerative Changes of Brain.
Thymoquinone Attenuates Brain Injury via an Anti-oxidative Pathway in a Status Epilepticus Rat Model.
A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing.
Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts.
Anthocyanins Delay Ageing-Related Degenerative Changes in the Liver.
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models.
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay.
MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5.
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
MiR-466b-1-3p regulates P-glycoprotein expression in rat cerebral microvascular endothelial cells.
Vav1 expression is increased in esophageal squamous cell carcinoma and indicates poor prognosis.
Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.
Achaete-Scute Homolog 1 Expression Controls Cellular Differentiation of Neuroblastoma.
Sulforaphane induces apoptosis and inhibits invasion in U251MG glioblastoma cells.
Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.
Rabies virus inactivates cofilin to facilitate viral budding and release.
Toll-like receptor 2-mediated MAPKs and NF-κB activation requires the GNAO1-dependent pathway in human mast cells.
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis.
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.
Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.
Polypeptide N-Acetylgalactosaminyltransferase 13 Contributes to Neurogenesis via Stabilizing the Mucin-type O-Glycoprotein Podoplanin.
Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies.
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.
Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells.
Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochlea.
miR-1301 promotes prostate cancer proliferation through directly targeting PPP2R2C.
MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2.
Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells.
PfIRR Interacts with HrIGF-I and Activates the MAP-kinase and PI3-kinase Signaling Pathways to Regulate Glycogen Metabolism in Pinctada fucata.
Nogo-B receptor promotes the chemoresistance of human hepatocellular carcinoma via the ubiquitination of p53 protein.
Spatially coordinated dynamic gene transcription in living pituitary tissue.
Anxa5 mediates the in vitro malignant behaviours of murine hepatocarcinoma Hca-F cells with high lymph node metastasis potential preferentially via ERK2/p-ERK2/c-Jun/p-c-Jun(Ser73) and E-cadherin.
Protective Effects of Thymoquinone Against Convulsant Activity Induced by Lithium-Pilocarpine in a model of Status Epilepticus.
Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats.
SUMOylated MAFB promotes colorectal cancer tumorigenesis.
Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity.
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
miR-935 promotes gastric cancer cell proliferation by targeting SOX7.
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
ZBTB20 is required for anterior pituitary development and lactotrope specification.
Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation.
Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells.
High expression of transforming acidic coiled coil-containing protein 3 strongly correlates with aggressive characteristics and poor prognosis of gastric cancer.
Adipose-derived mesenchymal stem cells promote cell proliferation and invasion of epithelial ovarian cancer.
The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma.
Real Time Monitoring of Inhibition of Adipogenesis and Angiogenesis by (-)-Epigallocatechin-3-Gallate in 3T3-L1 Adipocytes and Human Umbilical Vein Endothelial Cells.
P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury.
Proteomic characterization of the nucleolar linker histone H1 interaction network.
Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells.
Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Shear-sensitive microRNA-34a modulates flow-dependent regulation of endothelial inflammation.
Cytoplasmic hnRNPK interacts with GSK3β and is essential for the osteoclast differentiation.
IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.
Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Novel approaches for the identification of nuclear transport receptor substrates.
Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells.
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers.
Chromatin-remodeling factors mediate the balance of sense-antisense transcription at the FGF2 locus.
Pin1 promotes GR transactivation by enhancing recruitment to target genes.
Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.
Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.
Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy.
Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes.
Intercellular transportation of quantum dots mediated by membrane nanotubes.
Regulation of FGF-2 by an endogenous antisense RNA: effects on cell adhesion and cell-cycle progression.
Regulation of fibroblast growth factor-2 by an endogenous antisense RNA and by argonaute-2.
CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells.
Tang G, Du Y, Guan H, Jia J, Zhu N, Shi Y, Rong S, Yuan W
British journal of pharmacology 2022 Jan;179(1):159-178
British journal of pharmacology 2022 Jan;179(1):159-178
Virus-induced FoxO factor facilitates replication of human cytomegalovirus.
Sleman S
Archives of virology 2022 Jan;167(1):109-121
Archives of virology 2022 Jan;167(1):109-121
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Su P, Tian Y, Yin C, Wang X, Li D, Yang C, Pei J, Deng X, King S, Li Y, Qian A
Bone 2022 Jan;154:116238
Bone 2022 Jan;154:116238
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Zhou YH, Tang YZ, Guo LY, Zheng LL, Zhang D, Yang CY, Wang W
Microvascular research 2022 Jan;139:104252
Microvascular research 2022 Jan;139:104252
αTAT1-induced tubulin acetylation promotes ameloblastoma migration and invasion.
Yoshimoto S, Morita H, Okamura K, Hiraki A, Hashimoto S
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):80-89
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):80-89
Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2+ diffuse large B-cell lymphomas.
Shen Y, Zhou J, Nie K, Cheng S, Chen Z, Wang W, Wei W, Jiang D, Peng Z, Ren Y, Zhang Y, Fan Q, Richards KL, Qi Y, Cheng J, Tam W, Ma J
Blood 2022 Jan 6;139(1):73-86
Blood 2022 Jan 6;139(1):73-86
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Xu LT, Wang T, Fang KL, Zhao Y, Wang XN, Ren DM, Shen T
Journal of ethnopharmacology 2022 Jan 30;283:114694
Journal of ethnopharmacology 2022 Jan 30;283:114694
KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.
Ye MS, Luo L, Guo Q, Su T, Cheng P, Huang Y
The Journal of endocrinology 2022 Jan 13;252(3):155-166
The Journal of endocrinology 2022 Jan 13;252(3):155-166
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
Zhang Y, Zhang X, Dai K, Zhu M, Liang Z, Pan J, Zhang Z, Xue R, Cao G, Hu X, Gong C
International journal of biological macromolecules 2022 Jan 1;194:223-232
International journal of biological macromolecules 2022 Jan 1;194:223-232
High PHD Finger Protein 19 (PHF19) expression predicts poor prognosis in colorectal cancer: a retrospective study.
Li P, Sun J, Ruan Y, Song L
PeerJ 2021;9:e11551
PeerJ 2021;9:e11551
Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure.
Wang C, Feng Y, Zhou WJ, Cheng ZJ, Jiang MY, Zhou Y, Fei XY
PeerJ 2021;9:e11009
PeerJ 2021;9:e11009
MicroRNA-222 Transferred From Semen Extracellular Vesicles Inhibits Sperm Apoptosis by Targeting BCL2L11.
Ding Y, Ding N, Zhang Y, Xie S, Huang M, Ding X, Dong W, Zhang Q, Jiang L
Frontiers in cell and developmental biology 2021;9:736864
Frontiers in cell and developmental biology 2021;9:736864
Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway.
Deng M, Tan J, Dai Q, Luo F, Xu J
Frontiers in cell and developmental biology 2021;9:714011
Frontiers in cell and developmental biology 2021;9:714011
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Bai C, Wang H, Dong D, Li T, Yu Z, Guo J, Zhou W, Li D, Yan R, Wang L, Wang Z, Li Y, Ren L
Frontiers in cell and developmental biology 2021;9:650748
Frontiers in cell and developmental biology 2021;9:650748
RBM14 Modulates Tubulin Acetylation and Regulates Spindle Morphology During Meiotic Maturation in Mouse Oocytes.
Qin H, Qu Y, Yuan YF, Li YY, Qiao J
Frontiers in cell and developmental biology 2021;9:635728
Frontiers in cell and developmental biology 2021;9:635728
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Li Y, Xie KF, Chang YH, Wang C, Chen Y, Wang MJ, Zhu YC
Frontiers in cardiovascular medicine 2021;8:737191
Frontiers in cardiovascular medicine 2021;8:737191
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Liu Y, Liu P, Hu Y, Cao Y, Lu J, Yang Y, Lv H, Lian S, Xu B, Li S
Frontiers in molecular biosciences 2021;8:685993
Frontiers in molecular biosciences 2021;8:685993
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Huang X, Yan Y, Zheng W, Ma Y, Wang X, Gong W, Nie S
Frontiers in cardiovascular medicine 2021;8:682409
Frontiers in cardiovascular medicine 2021;8:682409
Network-Based Expression Analyses and Experimental Verifications Reveal the Involvement of STUB1 in Acute Kidney Injury.
Shi Y, Chen G, Teng J
Frontiers in molecular biosciences 2021;8:655361
Frontiers in molecular biosciences 2021;8:655361
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
Yang B, Chen J, Teng Y
Journal of immunology research 2021;2021:9994004
Journal of immunology research 2021;2021:9994004
Brusatol Inhibits Tumor Growth and Increases the Efficacy of Cabergoline against Pituitary Adenomas.
Wu Z, Xu Y, Xu J, Lu J, Cai L, Li Q, Wang C, Su Z
Oxidative medicine and cellular longevity 2021;2021:6696015
Oxidative medicine and cellular longevity 2021;2021:6696015
Glucagon-like Peptide-1 Improves Fatty Liver and Enhances Thermogenesis in Brown Adipose Tissue via Inhibiting BMP4-Related Signaling Pathway in High-Fat-Diet-Induced Obese Mice.
Wang X, Ma B, Chen J, You H, Sheng C, Yang P, Qu S
International journal of endocrinology 2021;2021:6620289
International journal of endocrinology 2021;2021:6620289
USP1 Promotes GC Metastasis via Stabilizing ID2.
Li N, Wu L, Zuo X, Luo H, Sheng Y, Yan J
Disease markers 2021;2021:3771990
Disease markers 2021;2021:3771990
Generation of VEGF knock-in Cashmere goat via the CRISPR/Cas9 system.
Hu X, Hao F, Li X, Xun Z, Gao Y, Ren B, Cang M, Liang H, Liu D
International journal of biological sciences 2021;17(4):1026-1040
International journal of biological sciences 2021;17(4):1026-1040
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
Bao D, Su H, Lei CT, Tang H, Ye C, Xiong W, He FF, Lin JH, Hammes HP, Zhang C
International journal of biological sciences 2021;17(15):4396-4408
International journal of biological sciences 2021;17(15):4396-4408
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Pang Z, Jiang Z, Zhu R, Song C, Tang H, Cao L, Guo C
Drug design, development and therapy 2021;15:3735-3747
Drug design, development and therapy 2021;15:3735-3747
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Wu R, Wang H, Huangfu J, Xiao R
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis.
Jin Y, Kang Y, Peng X, Yang L, Li Q, Mei Q, Chen X, Hu G, Tang Y, Yuan X
OncoTargets and therapy 2021;14:1911-1922
OncoTargets and therapy 2021;14:1911-1922
STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.
Wang X, Ding X, Yan J, Lu Z, Cao H, Ni X, Ying Y
American journal of translational research 2021;13(3):1422-1431
American journal of translational research 2021;13(3):1422-1431
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Zhai W, Li Y, Luo Y, Gao W, Liu S, Han J, Geng J
American journal of translational research 2021;13(10):11302-11315
American journal of translational research 2021;13(10):11302-11315
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Wang L, Huang Y, Liu C, Guo M, Ma Z, He J, Wang A, Sun X, Liu Z
Journal of Cancer 2021;12(3):860-873
Journal of Cancer 2021;12(3):860-873
Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2.
Li S, Ye M, Chen Y, Zhang Y, Li J, Liu W, Li H, Peng K
Frontiers in pharmacology 2021;12:735223
Frontiers in pharmacology 2021;12:735223
Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting.
Li L, Liu H, Tao W, Wen S, Fu X, Yu S
Frontiers in pharmacology 2021;12:731386
Frontiers in pharmacology 2021;12:731386
Identification of a Novel Epigenetic Signature CHFR as a Potential Prognostic Gene Involved in Metastatic Clear Cell Renal Cell Carcinoma.
Chen X, Lin J, Chen Q, Liao X, Wang T, Li S, Mao L, Li Z
Frontiers in genetics 2021;12:720979
Frontiers in genetics 2021;12:720979
Effect of Xanthium Strumarium on HIV-1 5'-LTR Transcriptional Activity and Viral Reactivation in Latently Infected Cells.
Chen CJ, Chiu ML, Hung CH, Liang WM, Ho MW, Lin TH, Liu X, Tsang H, Liao CC, Huang SM, Wu YF, Wu YC, Li TM, Tsai FJ, Lin YJ
Frontiers in pharmacology 2021;12:720821
Frontiers in pharmacology 2021;12:720821
Activation of STING Pathway Contributed to Cisplatin-Induced Cardiac Dysfunction via Promoting the Activation of TNF-α-AP-1 Signal Pathway.
Wang L, Zhang S, Han J, Nie X, Qi Y, Han Y, Chen X, He C
Frontiers in pharmacology 2021;12:711238
Frontiers in pharmacology 2021;12:711238
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
You S, Xu J, Wu B, Wu S, Zhang Y, Sun Y, Zhang N
Frontiers in genetics 2021;12:698570
Frontiers in genetics 2021;12:698570
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Gao W, Wen H, Liang L, Dong X, Du R, Zhou W, Zhang X, Zhang C, Xiang R, Li N
Theranostics 2021;11(6):2564-2580
Theranostics 2021;11(6):2564-2580
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
Wang YL, Wei MB, Zhao WW, Feng LL, Yin XK, Bai SM, Wan XB, Hung MC, Zou AZ, Wang MH, Zheng J, Qin C, Fan XJ
American journal of cancer research 2021;11(5):2291-2302
American journal of cancer research 2021;11(5):2291-2302
Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway.
Lee MJ, Lee JC, Hsieh JH, Lin MY, Shih IA, You HL, Wang K
American journal of cancer research 2021;11(4):1247-1266
American journal of cancer research 2021;11(4):1247-1266
Potential Role of SWI/SNF Complex Subunit Actin-Like Protein 6A in Cervical Cancer.
Wang Q, Cao Z, Wei Y, Zhang J, Cheng Z
Frontiers in oncology 2021;11:724832
Frontiers in oncology 2021;11:724832
Periodontal Pathogens Promote Oral Squamous Cell Carcinoma by Regulating ATR and NLRP3 Inflammasome.
Yao Y, Shen X, Zhou M, Tang B
Frontiers in oncology 2021;11:722797
Frontiers in oncology 2021;11:722797
Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.
Zhang Y, Wang D, Lv B, Hou X, Liu Q, Liao C, Xu R, Zhang Y, Xu F, Zhang P
Frontiers in oncology 2021;11:685059
Frontiers in oncology 2021;11:685059
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Gou R, Hu Y, Liu O, Dong H, Gao L, Wang S, Zheng M, Li X, Lin B
Frontiers in oncology 2021;11:682461
Frontiers in oncology 2021;11:682461
Identification METTL18 as a Potential Prognosis Biomarker and Associated With Immune Infiltrates in Hepatocellular Carcinoma.
Li TH, Qin C, Zhao BB, Cao HT, Yang XY, Wang YY, Li ZR, Zhou XT, Wang WB
Frontiers in oncology 2021;11:665192
Frontiers in oncology 2021;11:665192
Targeting Mutated p53 Dependency in Triple-Negative Breast Cancer Cells Through CDK7 Inhibition.
Peng J, Yang M, Bi R, Wang Y, Wang C, Wei X, Zhang Z, Xie X, Wei W
Frontiers in oncology 2021;11:664848
Frontiers in oncology 2021;11:664848
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
Shi S, Li C, Zhang Y, Deng C, Liu W, Du J, Li Q, Ji Y, Guo L, Liu L, Hu H, Liu Y, Cui H
Frontiers in oncology 2021;11:648052
Frontiers in oncology 2021;11:648052
Salmonella Effector SpvB Inhibits NF-κB Activity via KEAP1-Mediated Downregulation of IKKβ.
Yang S, Deng Q, Sun L, Zhu Y, Dong K, Wu S, Huang R, Li Y
Frontiers in cellular and infection microbiology 2021;11:641412
Frontiers in cellular and infection microbiology 2021;11:641412
Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis.
Li LM, Chen C, Ran RX, Huang JT, Sun HL, Zeng C, Zhang Z, Zhang W, Liu SM
Frontiers in oncology 2021;11:620912
Frontiers in oncology 2021;11:620912
Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of sirtuin 1.
Zhang L, Zheng J, Tie X, Lin T, Yang W, Li Z, Zou Y, Guan G, Liu P, Luo W, Li Z
Canadian journal of physiology and pharmacology 2021 Sep;99(9):900-909
Canadian journal of physiology and pharmacology 2021 Sep;99(9):900-909
Inhibitory effect of HTLV-1 infection on the production of B-cell activating factors in established follicular dendritic cell-like cells.
Takatani A, Nakamura H, Furukawa K, Endo Y, Umeda M, Shimizu T, Nishihata SY, Kitaoka K, Nakamura T, Kawakami A
Immunity, inflammation and disease 2021 Sep;9(3):777-791
Immunity, inflammation and disease 2021 Sep;9(3):777-791
Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder.
Snelleksz M, Dean B
Psychiatry research 2021 Sep;303:114096
Psychiatry research 2021 Sep;303:114096
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Zhang Z, Zheng Y, Niu Z, Zhang B, Wang C, Yao X, Peng H, Franca DN, Wang Y, Zhu Y, Su Y, Tang M, Jiang X, Ren H, He M, Wang Y, Gao L, Zhao P, Shi H, Chen Z, Wang X, Piacentini M, Bian X, Melino G, Liu L, Huang H, Sun Q
Cell death and differentiation 2021 Sep;28(9):2765-2777
Cell death and differentiation 2021 Sep;28(9):2765-2777
The inhibitory effect of the deubiquitinase cylindromatosis (CYLD) on inflammatory responses in human gingival fibroblasts.
Fu YW, Li L, Wang XQ, Zhou Y, Zhu LF, Mei YM, Xu Y
Oral diseases 2021 Sep;27(6):1487-1497
Oral diseases 2021 Sep;27(6):1487-1497
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
Li Y, Su Y, Zhao Y, Hu X, Zhao G, He J, Wan S, Lü M, Cui H
MedComm 2021 Sep;2(3):467-480
MedComm 2021 Sep;2(3):467-480
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
Du Y, Zhang M, Liu X, Li Z, Hu M, Tian Y, Lv L, Zhang X, Liu Y, Zhang P, Zhou Y
EMBO reports 2021 Sep 6;22(9):e52576
EMBO reports 2021 Sep 6;22(9):e52576
PEX5 prevents cardiomyocyte hypertrophy via suppressing the redox-sensitive signaling pathways MAPKs and STAT3.
Wang M, Li J, Ding Y, Cai S, Li Z, Liu P
European journal of pharmacology 2021 Sep 5;906:174283
European journal of pharmacology 2021 Sep 5;906:174283
Matrine injection inhibits pancreatic cancer growth via modulating carbonic anhydrases- a network pharmacology-based study with in vitro validation.
Xu PL, Cheng CS, Jiao JY, Chen H, Chen Z, Li P
Journal of ethnopharmacology 2021 Sep 29;287:114691
Journal of ethnopharmacology 2021 Sep 29;287:114691
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling.
Liu A, Xie H, Li R, Ren L, Yang B, Dai L, Lu W, Liu B, Ren D, Zhang X, Chen Q, Huang Y, Shi K
Molecular therapy oncolytics 2021 Sep 24;22:195-208
Molecular therapy oncolytics 2021 Sep 24;22:195-208
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome.
Peoples JN, Ghazal N, Duong DM, Hardin KR, Manning JR, Seyfried NT, Faundez V, Kwong JQ
American journal of physiology. Cell physiology 2021 Sep 1;321(3):C519-C534
American journal of physiology. Cell physiology 2021 Sep 1;321(3):C519-C534
The protective effect of isoflurane pretreatment on liver IRI by suppressing noncanonical pyroptosis of liver macrophages.
Lu J, Wang X, Feng Z, Chen Y, Wen D, Liu Z
International immunopharmacology 2021 Oct;99:107977
International immunopharmacology 2021 Oct;99:107977
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Liu W, Liang L, Zhang Q, Li Y, Yan S, Tang T, Ren Y, Mo J, Liu F, Chen X, Lan T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Assembly of Cytoplasmic Stress Granules in Placentas in Women with Preeclampsia.
Ma C, Li C, Shao S, Li C, Yu S, Zhao L, Li Y, Zhao S
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2869-2877
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2869-2877
Oxidized phospholipids on alkyl-amide scaffold demonstrate anti-endotoxin and endothelial barrier-protective properties.
Oskolkova OV, Hodzic A, Karki P, Gesslbauer B, Ke Y, Hofer DC, Bogner-Strauss JG, Galano JM, Oger C, Birukova A, Durand T, Birukov K, Bochkov V
Free radical biology & medicine 2021 Oct;174:264-271
Free radical biology & medicine 2021 Oct;174:264-271
Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases.
Arnould H, Baudouin V, Baudry A, Ribeiro LW, Ardila-Osorio H, Pietri M, Caradeuc C, Soultawi C, Williams D, Alvarez M, Crozet C, Djouadi F, Laforge M, Bertho G, Kellermann O, Launay JM, Schmitt-Ulms G, Schneider B
PLoS pathogens 2021 Oct;17(10):e1009991
PLoS pathogens 2021 Oct;17(10):e1009991
Deacetylation of BmAda3 is required for cell apoptosis caused by Bombyx mori nucleopolyhedrovirus infection.
Zhu Y, Hu M, Ngowo J, Gao X, Chen X, Yan H, Yu W
Archives of insect biochemistry and physiology 2021 Oct;108(2):e21838
Archives of insect biochemistry and physiology 2021 Oct;108(2):e21838
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Li Y, Sun X, Bai Y, Ji Y, Ren H, Yu X, Yan Y, He X, Dong Y, Zhang L, Luo X, Wang H
Aging 2021 Oct 5;13(19):22985-23003
Aging 2021 Oct 5;13(19):22985-23003
Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment.
Hou Y, Kuang W, Min W, Liu Z, Zhang F, Yuan K, Wang X, Sun C, Cheng H, Wang L, Xiao Y, Pu S, Xin GZ, Yang P
Journal of medicinal chemistry 2021 Oct 28;64(20):14942-14954
Journal of medicinal chemistry 2021 Oct 28;64(20):14942-14954
Folic Acid-Appended Hydroxypropyl-β-Cyclodextrin Exhibits Potent Antitumor Activity in Chronic Myeloid Leukemia Cells via Autophagic Cell Death.
Hoshiko T, Kubota Y, Onodera R, Higashi T, Yokoo M, Motoyama K, Kimura S
Cancers 2021 Oct 28;13(21)
Cancers 2021 Oct 28;13(21)
19-Hydroxybufalin inhibits non-small cell lung cancer cell proliferation and promotes cell apoptosis via the Wnt/β-catenin pathway.
Yu W, Zhang X, Zhang W, Xiong M, Lin Y, Chang M, Xu L, Lu Y, Liu Y, Zhang J
Experimental hematology & oncology 2021 Oct 25;10(1):48
Experimental hematology & oncology 2021 Oct 25;10(1):48
CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis.
Ding S, Lan X, Meng Y, Yan C, Li M, Li X, Chen J, Jiang W
Cell death & disease 2021 Oct 22;12(11):981
Cell death & disease 2021 Oct 22;12(11):981
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Zhang J, Zou L, Shi D, Liu J, Zhang J, Zhao R, Wang G, Zhang L, Ouyang L, Liu B
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Bortezomib potentiates antitumor activity of mitoxantrone through dampening Wnt/β-catenin signal pathway in prostate cancer cells.
Zhang Y, Liu Q, Wei W, Zhang G, Yan S, Dai R, Sun Y, Su D, Lv S, Xia Y, Li J, Li C
BMC cancer 2021 Oct 13;21(1):1101
BMC cancer 2021 Oct 13;21(1):1101
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936
Cell death & disease 2021 Oct 12;12(10):936
ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation.
Wang Y, Fan J, Wang J, Zhu Y, Xu L, Tong D, Cheng H
Nucleic acids research 2021 Oct 11;49(18):10630-10643
Nucleic acids research 2021 Oct 11;49(18):10630-10643
FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination.
Ma L, Li W, Zhang Y, Qi L, Zhao Q, Li N, Lu Y, Zhang L, Zhou F, Wu Y, He Y, Yu H, He Y, Wei B, Wang H
Autophagy 2021 Oct 10;:1-16
Autophagy 2021 Oct 10;:1-16
Effects and Mechanisms of Synaptotagmin-7 in the Hippocampus on Cognitive Impairment in Aging Mice.
Xie Y, Zhi K, Meng X
Molecular neurobiology 2021 Nov;58(11):5756-5771
Molecular neurobiology 2021 Nov;58(11):5756-5771
C23 gene regulates the nucleolin structure and biosynthesis of ribosomes in bovine intraspecific and interspecific somatic cell nuclear transfer embryos.
Su G, Wang L, Gao G, Wu S, Yang L, Wu M, Liu X, Yang M, Wei Z, Bai C, Li G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21993
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21993
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Dong Z, Qiu T, Zhang J, Sha S, Han X, Kang J, Shi X, Sun X, Jiang L, Yang G, Yao X, Ma Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
WIPI-1 inhibits metastasis and tumour growth via the WIPI-1-TRIM21 axis and MYC regulation in nasopharyngeal carcinoma.
Zhao Y, Li WF, Li QJ, He SW, He QM, Long LF, Liu N, Ma J
Oral oncology 2021 Nov;122:105576
Oral oncology 2021 Nov;122:105576
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
Lu Z, Huang L, Li Y, Xu Y, Zhang R, Zhou Q, Sun Q, Lu Y, Chen J, Shen Y, Li J, Zhao B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov 5;:e2102669
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Nov 5;:e2102669
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Hao K, Chen Y, Yan X, Zhu X
Nature communications 2021 Nov 30;12(1):6971
Nature communications 2021 Nov 30;12(1):6971
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Gao X, Shen X, Zheng Y, Yang L, Zhang X, Hu G, Jia J, Wang A
Journal of natural products 2021 Nov 26;84(11):2808-2821
Journal of natural products 2021 Nov 26;84(11):2808-2821
LncRNA Riken Attenuated Sevoflurane-Induced Neuroinflammation by Regulating the MicroRNA-101a/MKP-1/JNK Pathway.
Hou Q, Li S, Zhang B, Chu H, Ni C, Fei X, Zheng H
Neurotoxicity research 2021 Nov 26;
Neurotoxicity research 2021 Nov 26;
The Acetylation Modification of SP1 Regulates the Protein Stability in Silkworm.
Sun Z, Ma Y, Liu Y, Lv J, Wang D, You Z, Jiang C, Sheng Q, Nie Z
Applied biochemistry and biotechnology 2021 Nov 26;
Applied biochemistry and biotechnology 2021 Nov 26;
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
Li B, Ye J, Liu R, Weng L, Cao Y, Jia S, Xu C, Liu Y, Yan S, Zheng M
Life sciences 2021 Nov 15;285:119918
Life sciences 2021 Nov 15;285:119918
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS
Nature communications 2021 Nov 15;12(1):6602
Nature communications 2021 Nov 15;12(1):6602
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
Zheng L, Ren R, Sun X, Zou Y, Shi Y, Di B, Niu MM
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
The deubiquitinating enzyme ATXN3 promotes the progression of anaplastic thyroid carcinoma by stabilizing EIF5A2.
Zhuang S, Xie J, Zhen J, Guo L, Hong Z, Li F, Xu D
Molecular and cellular endocrinology 2021 Nov 1;537:111440
Molecular and cellular endocrinology 2021 Nov 1;537:111440
TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration.
Li M, Zhu H, Hu X, Gao F, Hu X, Cui Y, Wei X, Xie C, Lv G, Zhao Y, Gao Y
Canadian journal of physiology and pharmacology 2021 May;99(5):536-548
Canadian journal of physiology and pharmacology 2021 May;99(5):536-548
W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319.
Zhong L, Liu Q, Liu Q, Zhang S, Cao Y, Yang D, Wang MW
Chemical biology & drug design 2021 May;97(5):1089-1099
Chemical biology & drug design 2021 May;97(5):1089-1099
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage.
Wu B, Wu Y, Fan C, Feng C, Wang H, Bai F, Zuo J, Tang W
International immunopharmacology 2021 May;94:107482
International immunopharmacology 2021 May;94:107482
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
Zhang W, Chen H, Ding L, Gong J, Zhang M, Guo W, Xu P, Li S, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2004555
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2004555
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Li C, Li L, Ali I, Kuang M, Wang X, Wang G
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
Role of epigenetic m6 A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR-AKT signaling.
Parial R, Li H, Li J, Archacki S, Yang Z, Wang IZ, Chen Q, Xu C, Wang QK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21465
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21465
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
Guo C, Li N, Dong C, Wang L, Li Z, Liu Q, Ma Q, Greenaway FT, Tian Y, Hao L, Liu S, Sun MZ
Journal of advanced research 2021 May;30:85-102
Journal of advanced research 2021 May;30:85-102
Nicotine-derived NNK induces the stemness enrichment of CRC cells through regulating the balance of DUSP4-ERK1/2 feedback loop.
Chen Y, Wang Q, Cao L, Tang Y, Yao M, Bi H, Huang Y, Sun G, Song J
Ecotoxicology and environmental safety 2021 May;214:112057
Ecotoxicology and environmental safety 2021 May;214:112057
mTOR regulates PRMT1 expression and mitochondrial mass through STAT1 phosphorylation in hepatic cell.
Zhang X, Li L, Li Y, Li Z, Zhai W, Sun Q, Yang X, Roth M, Lu S
Biochimica et biophysica acta. Molecular cell research 2021 May;1868(6):119017
Biochimica et biophysica acta. Molecular cell research 2021 May;1868(6):119017
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Yao Y, Liu W, Gajendran B, Wang C, Zacksenhaus E, Sample KM, Varier KM, Hao X, Ben-David Y
Biochimie 2021 May;184:8-17
Biochimie 2021 May;184:8-17
Pathogenesis of acephalic spermatozoa syndrome caused by SUN5 variant.
Zhang D, Huang WJ, Chen GY, Dong LH, Tang Y, Zhang H, Li QQ, Mei XY, Wang ZH, Lan FH
Molecular human reproduction 2021 May 8;27(5)
Molecular human reproduction 2021 May 8;27(5)
Ggps1 deficiency in the uterus results in dystocia by disrupting uterine contraction.
Sang YJ, Wang Q, Zheng F, Hua Y, Wang XY, Zhang JZ, Li K, Wang HQ, Zhao Y, Zhu MS, Sun HX, Li CJ
Journal of molecular cell biology 2021 May 7;13(2):116-127
Journal of molecular cell biology 2021 May 7;13(2):116-127
Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma.
Nepali K, Hsu TI, Hsieh CM, Lo WL, Lai MJ, Hsu KC, Lin TE, Chuang JY, Liou JP
European journal of medicinal chemistry 2021 May 5;217:113338
European journal of medicinal chemistry 2021 May 5;217:113338
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer.
Han Z, Zhang W, Ning W, Wang C, Deng W, Li Z, Shang Z, Shen X, Liu X, Baba O, Morita T, Chen L, Xue Y, Jia D
Nature communications 2021 May 31;12(1):3258
Nature communications 2021 May 31;12(1):3258
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Wang Q, Xin Q, Shang W, Wan W, Xiao G, Zhang LK
Viruses 2021 May 25;13(6)
Viruses 2021 May 25;13(6)
Genistein suppresses allergic contact dermatitis through regulating the MAP2K2/ERK pathway.
Xu J, Xiong H, Zhao Z, Luo M, Ju Y, Yang G, Mei Z
Food & function 2021 May 21;12(10):4556-4569
Food & function 2021 May 21;12(10):4556-4569
HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.
Song D, Guo M, Xu S, Song X, Bai B, Li Z, Chen J, An Y, Nie Y, Wu K, Wang S, Zhao Q
Journal of experimental & clinical cancer research : CR 2021 May 14;40(1):170
Journal of experimental & clinical cancer research : CR 2021 May 14;40(1):170
H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes.
Lin J, Wei J, Lv Y, Zhang X, Yi RF, Dai C, Zhang Q, Jia J, Zhang D, Huang Y
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Butyrate alleviates PTZ-induced mitochondrial dysfunction, oxidative stress and neuron apoptosis in mice via Keap1/Nrf2/HO-1 pathway.
Li D, Bai X, Jiang Y, Cheng Y
Brain research bulletin 2021 Mar;168:25-35
Brain research bulletin 2021 Mar;168:25-35
Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics.
Tang FL, Wang J, Itokazu Y, Yu RK
Journal of neurochemistry 2021 Mar;156(6):819-833
Journal of neurochemistry 2021 Mar;156(6):819-833
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
Bian X, Shi D, Xing K, Zhou H, Lu L, Yu D, Wu W
Clinical and translational medicine 2021 Mar;11(3):e352
Clinical and translational medicine 2021 Mar;11(3):e352
USP34 regulates tooth root morphogenesis by stabilizing NFIC.
Jiang S, Sheng R, Qi X, Wang J, Guo Y, Yuan Q
International journal of oral science 2021 Mar 9;13(1):7
International journal of oral science 2021 Mar 9;13(1):7
Endometrial cell-derived small extracellular vesicle miR-100-5p promotes functions of trophoblast during embryo implantation.
Tan Q, Shi S, Liang J, Cao D, Wang S, Wang Z
Molecular therapy. Nucleic acids 2021 Mar 5;23:217-231
Molecular therapy. Nucleic acids 2021 Mar 5;23:217-231
Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN.
Tian M, Wang J, Liu S, Li X, Li J, Yang J, Zhang C, Zhang W
Cell death & disease 2021 Mar 4;12(3):236
Cell death & disease 2021 Mar 4;12(3):236
HN1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by interacting with STMN1.
Pan Z, Fang Q, Li L, Zhang Y, Xu T, Liu Y, Zheng X, Tan Z, Huang P, Ge M
Cancer letters 2021 Mar 31;501:31-42
Cancer letters 2021 Mar 31;501:31-42
SIRT1 inhibitors mitigate radiation-induced GI syndrome by enhancing intestinal-stem-cell survival.
Fu G, Chen S, Liang L, Li X, Tang P, Rao X, Pan M, Xu X, Li Y, Yao Y, Zhou Y, Gao J, Mo S, Cai S, Peng J, Zhang Z, Clevers H, Gao J, Hua G
Cancer letters 2021 Mar 31;501:20-30
Cancer letters 2021 Mar 31;501:20-30
Selenite Inhibits Notch Signaling in Cells and Mice.
Powers M, Liu L, Deemer D, Chen S, Scholl A, Yoshinaga M, Liu Z
International journal of molecular sciences 2021 Mar 3;22(5)
International journal of molecular sciences 2021 Mar 3;22(5)
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Zhu S, Liang J, Zhu F, Zhang X, Xu M, Zhao K, Zeng L, Xu K
Bioscience reports 2021 Mar 26;41(3)
Bioscience reports 2021 Mar 26;41(3)
Hypoxic training upregulates mitochondrial turnover and angiogenesis of skeletal muscle in mice.
Zhao YC, Guo W, Gao BH
Life sciences 2021 Mar 11;291:119340
Life sciences 2021 Mar 11;291:119340
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Wang J, Li Z, Yang X, Qiao Y, Feng C, Yu S, Jing H, Liu W, Ren L, Duan Q, Li XQ, Cao W
Carbohydrate polymers 2021 Mar 1;255:117532
Carbohydrate polymers 2021 Mar 1;255:117532
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Qu H, Gong X, Liu X, Zhang R, Wang Y, Huang B, Zhang L, Zheng H, Zheng Y
Diabetes 2021 Jun;70(6):1372-1387
Diabetes 2021 Jun;70(6):1372-1387
Tanshinone IIA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehydrogenase in macrophages.
Liu QY, Zhuang Y, Song XR, Niu Q, Sun QS, Li XN, Li N, Liu BL, Huang F, Qiu ZX
Acta pharmacologica Sinica 2021 Jun;42(6):987-997
Acta pharmacologica Sinica 2021 Jun;42(6):987-997
Protective effects of total flavonoids from Qu Zhi Qiao (fruit of Citrus paradisi cv. Changshanhuyou) on OVA-induced allergic airway inflammation and remodeling through MAPKs and Smad2/3 signaling pathway.
Wang J, Li T, Cai H, Jin L, Li R, Shan L, Cai W, Jiang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111421
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111421
Treg deficiency-mediated TH 1 response causes human premature ovarian insufficiency through apoptosis and steroidogenesis dysfunction of granulosa cells.
Jiao X, Zhang X, Li N, Zhang D, Zhao S, Dang Y, Zanvit P, Jin W, Chen ZJ, Chen W, Qin Y
Clinical and translational medicine 2021 Jun;11(6):e448
Clinical and translational medicine 2021 Jun;11(6):e448
Immunoprecipitation Strategies to Isolate RIPK1/RIPK3 Complexes in Mouse Macrophages.
Siokas I, Zhang D, Poltorak A, Muendlein H, Degterev A
Current protocols 2021 Jun;1(6):e156
Current protocols 2021 Jun;1(6):e156
A human β-casein-derived peptide BCCY-1 modulates the innate immune response.
Cai J, Li X, Wang X, Jiang C, Shen D, Cui X, Xie K, Ji C, Cao Y
Food chemistry 2021 Jun 30;348:129111
Food chemistry 2021 Jun 30;348:129111
Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.
Li G, LeiQian, Gu P, Fan D
BMC anesthesiology 2021 Jun 28;21(1):180
BMC anesthesiology 2021 Jun 28;21(1):180
DNA methylation mediated RSPO2 to promote follicular development in mammals.
Zhou X, He Y, Li N, Bai G, Pan X, Zhang Z, Zhang H, Li J, Yuan X
Cell death & disease 2021 Jun 26;12(7):653
Cell death & disease 2021 Jun 26;12(7):653
High expression of aryl hydrocarbon receptor (AhR) plays an important role in the formation of fibrous epulis.
Zeng X, Xia S, Yan X, Hu C, An K, Luo L
Oral diseases 2021 Jun 17;
Oral diseases 2021 Jun 17;
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Wang H, Yang C, Li Y, Zhao S, Ma P, Mao B
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes.
Li S, Cao W, Zhou S, Ma M, Zhang W, Li F, Li C
Brain, behavior, and immunity 2021 Jul;95:142-153
Brain, behavior, and immunity 2021 Jul;95:142-153
Engorgement of Rhipicephalus haemaphysaloides ticks blocked by silencing a protein inhibitor of apoptosis.
Tuerdi M, Hu S, Wang Y, Zhou Y, Cao J, Zhang H, Zhou J
Experimental & applied acarology 2021 Jul;84(3):623-636
Experimental & applied acarology 2021 Jul;84(3):623-636
Apoptotic caspases suppress Mycobacterium bovis-induced IFN-β production in murine macrophage.
Song Y, Dong Y, Liao Y, Liang Z, Yao J, Zhou X
The Journal of infection 2021 Jul;83(1):61-68
The Journal of infection 2021 Jul;83(1):61-68
Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin.
Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan JA, Zhang Y, Jiang Y, Wang Y, Lin RZ, Cong H, Gao S, Zong WX
EBioMedicine 2021 Jul;69:103456
EBioMedicine 2021 Jul;69:103456
Reconsolidation of a post-ingestive nutrient memory requires mTOR in the central amygdala.
Yan Y, Zhang L, Zhu T, Deng S, Ma B, Lv H, Shan X, Cheng H, Jiang K, Zhang T, Meng B, Mei B, Li WG, Li F
Molecular psychiatry 2021 Jul;26(7):2820-2836
Molecular psychiatry 2021 Jul;26(7):2820-2836
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Jia P, Wu N, Yang H, Guo Y, Guo X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
Luo P, He WX, Li C, Chang MJ
Neuroreport 2021 Jul 7;32(10):875-881
Neuroreport 2021 Jul 7;32(10):875-881
PKD2 deficiency suppresses amino acid biosynthesis in ADPKD by impairing the PERK-TBL2-eIF2ɑ-ATF4 pathway.
Zhou X, Xiong H, Lu Y, Geng M, Lu Y, Zhang L, Zhu X
Biochemical and biophysical research communications 2021 Jul 5;561:73-79
Biochemical and biophysical research communications 2021 Jul 5;561:73-79
Planar cell polarity induces local microtubule bundling for coordinated ciliary beating.
Nakayama S, Yano T, Namba T, Konishi S, Takagishi M, Herawati E, Nishida T, Imoto Y, Ishihara S, Takahashi M, Furuta K, Oiwa K, Tamura A, Tsukita S
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Cheng L, Chen T, Guo M, Liu P, Qiao X, Wei Y, She J, Li B, Xi W, Zhou J, Yuan Z, Wu Y, Liu J
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Liu K, Cui Y, Li H, Qi C, Cheng G, Gao X, Zhang Z, Liu Y, Liu J
Biological trace element research 2021 Jul 30;
Biological trace element research 2021 Jul 30;
Time-dependent expression of ryanodine receptors in sea urchin eggs, zygotes and early embryos.
Percivale G, Angelini C, Falugi C, Picco C, Prestipino G
Zygote (Cambridge, England) 2021 Jul 28;:1-4
Zygote (Cambridge, England) 2021 Jul 28;:1-4
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Luo W, Li J, Li Z, Lin T, Zhang L, Yang W, Mai Y, Liu R, Chen M, Dai C, Yang H, Lu J, Li H, Guan G, Huang M, Liu P, Li Z
Cell death & disease 2021 Jul 26;12(8):738
Cell death & disease 2021 Jul 26;12(8):738
Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation.
Li M, Liu H, Li J, Guo S, Lv Y
Respiratory research 2021 Jul 1;22(1):190
Respiratory research 2021 Jul 1;22(1):190
Actin-granule formation is an additional step in cardiac myofibroblast differentiation.
He L, Liu R, Yue H, Ren S, Zhu G, Guo Y, Qin C
Annals of translational medicine 2021 Jan;9(2):165
Annals of translational medicine 2021 Jan;9(2):165
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Bai Z, Ding N, Ge J, Wang Y, Wang L, Wu N, Wei Q, Xu S, Liu X, Zhou G
Cell biology international 2021 Jan;45(1):177-187
Cell biology international 2021 Jan;45(1):177-187
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Jiang Y, Xie F, Lv X, Wang S, Liao X, Yu Y, Dai Q, Zhang Y, Meng J, Hu G, Peng Z, Tao L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.
Zhang J, Chen Y, Chen X, Zhang W, Zhao L, Weng L, Tian H, Wu Z, Tan X, Ge X, Wang P, Fang L
Cell death and differentiation 2021 Jan;28(1):139-155
Cell death and differentiation 2021 Jan;28(1):139-155
The inhibition of colorectal cancer growth by the natural product macrocarpal I.
Qi L, Zhang Y, Zhang W, Wang Y, Han Y, Ding Y
Free radical biology & medicine 2021 Jan;162:383-391
Free radical biology & medicine 2021 Jan;162:383-391
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Tang C, Luo Y, Li S, Huang B, Xu S, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Li B, Wang Z, Hong J, Che Y, Chen R, Hu Z, Hu X, Wu Q, Hu J, Zhang M
Clinical and translational medicine 2021 Jan;11(1):e276
Clinical and translational medicine 2021 Jan;11(1):e276
Silencing integrin α6 enhances the pluripotency-differentiation transition in human dental pulp stem cells.
Zhang W, Shen J, Zhang S, Liu X, Pan S, Li Y, Zhang L, He L, Niu Y
Oral diseases 2021 Jan 6;
Oral diseases 2021 Jan 6;
Skip participates in formation and lipid metabolism of beige adipose and might mediate the effects of SIRT1 activator BTM-0512 on beige remodeling.
Liao ZM, Li AN, Cai Y, Chen JJ, Xu Y, Sui LH, Wang JL, Jin P, Wang KS, Yang ZC
Biochemical and biophysical research communications 2021 Jan 22;537:109-117
Biochemical and biophysical research communications 2021 Jan 22;537:109-117
CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9.
Zhang Y, Hou J, Shi S, Du J, Liu Y, Huang P, Li Q, Liu L, Hu H, Ji Y, Guo L, Shi Y, Liu Y, Cui H
Cell death & disease 2021 Jan 22;12(1):118
Cell death & disease 2021 Jan 22;12(1):118
Exosomes derived from thymic stromal lymphopoietin-treated dendritic cells regulate T helper 17/regulatory T cell differentiation via miR-21/Smad7 axis.
Ji Q, Liu J, Dong Y, Wang L, Dong K, Setiz B, Szentmáry N, Qu B, Shi L
Experimental cell research 2021 Jan 1;398(1):112393
Experimental cell research 2021 Jan 1;398(1):112393
Changes in the expression of endothelial monocyte‑activating polypeptide II in the rat hippocampus following status epilepticus.
Li C, Ma W, Zhao Y, Wang H
International journal of molecular medicine 2021 Feb;47(2):699-707
International journal of molecular medicine 2021 Feb;47(2):699-707
METTL3-Mediated m6 A mRNA Methylation Modulates Tooth Root Formation by Affecting NFIC Translation.
Sheng R, Wang Y, Wu Y, Wang J, Zhang S, Li Q, Zhang D, Qi X, Xiao Q, Jiang S, Yuan Q
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Feb;36(2):412-423
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Feb;36(2):412-423
Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer.
Jhou AJ, Chang HC, Hung CC, Lin HC, Lee YC, Liu WT, Han KF, Lai YW, Lin MY, Lee CH
Biochemical pharmacology 2021 Feb;184:114403
Biochemical pharmacology 2021 Feb;184:114403
Targeting ROCK1/2 blocks cell division and induces mitotic catastrophe in hepatocellular carcinoma.
Wu H, Chen Y, Li B, Li C, Guo J, You J, Hu X, Kuang D, Qi S, Liu P, Li L, Xu C
Biochemical pharmacology 2021 Feb;184:114353
Biochemical pharmacology 2021 Feb;184:114353
Knockdown of ASH1L methyltransferase induced apoptosis inhibiting proliferation and H3K36 methylation in bovine cumulus cells.
Cui LX, Tian YQ, Hao HS, Zou HY, Pang YW, Zhao SJ, Zhao XM, Zhu HB, Du WH
Theriogenology 2021 Feb;161:65-73
Theriogenology 2021 Feb;161:65-73
Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer's disease.
Liu X, Chu B, Jin S, Li M, Xu Y, Yang H, Feng Z, Bi J, Wang P
The International journal of neuroscience 2021 Feb;131(2):154-162
The International journal of neuroscience 2021 Feb;131(2):154-162
Integrated analysis of microRNA and mRNA expression profiling identifies BAIAP3 as a novel target of dysregulated hsa-miR-1972 in age-related white matter lesions.
Huang WQ, Lin Q, Chen S, Sun L, Chen Q, Yi K, Li Z, Ma Q, Tzeng CM
Aging 2021 Feb 9;13(3):4674-4695
Aging 2021 Feb 9;13(3):4674-4695
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Zhang Q, Chen W, Zhang B, Li C, Zhang X, Wang Q, Wang Y, Zhou Q, Li X, Shen XL
Toxicology 2021 Feb 28;450:152681
Toxicology 2021 Feb 28;450:152681
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
Li J, Liu F, Lv Y, Sun K, Zhao Y, Reilly J, Zhang Y, Tu J, Yu S, Liu X, Qin Y, Huang Y, Gao P, Jia D, Chen X, Han Y, Shu X, Luo D, Tang Z, Liu M
Nucleic acids research 2021 Feb 26;49(4):2027-2043
Nucleic acids research 2021 Feb 26;49(4):2027-2043
High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy.
Wu QR, Zheng DL, Liu PM, Yang H, Li LA, Kuang SJ, Lai YY, Rao F, Xue YM, Lin JJ, Liu SX, Chen CB, Deng CY
Cell death & disease 2021 Feb 26;12(2):216
Cell death & disease 2021 Feb 26;12(2):216
Aberrantly high activation of a FoxM1-STMN1 axis contributes to progression and tumorigenesis in FoxM1-driven cancers.
Liu J, Li J, Wang K, Liu H, Sun J, Zhao X, Yu Y, Qiao Y, Wu Y, Zhang X, Zhang R, Yang A
Signal transduction and targeted therapy 2021 Feb 1;6(1):42
Signal transduction and targeted therapy 2021 Feb 1;6(1):42
Semaphorin 3A promotes the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells in inflammatory environments by suppressing the Wnt/β-catenin signaling pathway.
Sun Z, Yan K, Liu S, Yu X, Xu J, Liu J, Li S
Journal of molecular histology 2021 Dec;52(6):1245-1255
Journal of molecular histology 2021 Dec;52(6):1245-1255
Histone Deacetylase Inhibitor SAHA Induces Expression of Fatty Acid-Binding Protein 4 and Inhibits Replication of Human Cytomegalovirus.
Liu Z, Xuan B, Tang S, Qian Z
Virologica Sinica 2021 Dec;36(6):1352-1362
Virologica Sinica 2021 Dec;36(6):1352-1362
Small molecule targeting topoisomerase 3β for cancer therapy.
Zhang X, Wang L, Zhang Q, Lyu S, Zhu D, Shen M, Ke X, Qu Y
Pharmacological research 2021 Dec;174:105927
Pharmacological research 2021 Dec;174:105927
Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells.
Alsharif S, Sharma P, Bursch K, Milliken R, Lam V, Fallatah A, Phan T, Collins M, Dohlman P, Tiufekchiev S, Nehmetallah G, Raub CB, Chung BM
Cell adhesion & migration 2021 Dec;15(1):1-17
Cell adhesion & migration 2021 Dec;15(1):1-17
Effects and mechanisms of probucol on aging-related hippocampus-dependent cognitive impairment.
Xie Y, Song A, Zhu Y, Jiang A, Peng W, Zhang C, Meng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112266
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112266
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Liu T, Yang Y, Xie Z, Luo Q, Yang D, Liu X, Zhao H, Wei Q, Liu Y, Li L, Wang Y, Wang F, Yu J, Xu J, Yu J, Yi P
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.
Zhang G, Li D, Tu C, Meng L, Tan Y, Ji Z, Cheng J, Lu G, Lin G, Zhang H, Sun J, Wang M, Du J, Xu W
Human molecular genetics 2021 Dec 27;31(2):219-231
Human molecular genetics 2021 Dec 27;31(2):219-231
GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity.
Peng Y, Zeng Q, Wan L, Ma E, Li H, Yang X, Zhang Y, Huang L, Lin H, Feng J, Xu Y, Li J, Liu M, Liu J, Lin C, Sun Z, Cheng G, Zhang X, Liu J, Li D, Wei M, Mo Y, Mu X, Deng X, Zhang D, Dong S, Huang H, Fang Y, Gao Q, Yang X, Wu F, Zhong H, Wei C
Nature communications 2021 Dec 1;12(1):7004
Nature communications 2021 Dec 1;12(1):7004
ZNRF2 attenuates focal cerebral ischemia/reperfusion injury in rats by inhibiting mTORC1-mediated autophagy.
Gu C, Yang J, Luo Y, Ran D, Tan X, Xiang P, Fei H, Lu Y, Guo W, Tu Y, Liu X, Wang H
Experimental neurology 2021 Aug;342:113759
Experimental neurology 2021 Aug;342:113759
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target.
Xia B, Shen X, He Y, Pan X, Liu FL, Wang Y, Yang F, Fang S, Wu Y, Duan Z, Zuo X, Xie Z, Jiang X, Xu L, Chi H, Li S, Meng Q, Zhou H, Zhou Y, Cheng X, Xin X, Jin L, Zhang HL, Yu DD, Li MH, Feng XL, Chen J, Jiang H, Xiao G, Zheng YT, Zhang LK, Shen J, Li J, Gao Z
Cell research 2021 Aug;31(8):847-860
Cell research 2021 Aug;31(8):847-860
Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage.
Dai C, Wu B, Chen Y, Li X, Bai Y, Du Y, Pang Y, Wang YT, Dong Z
Cell death and differentiation 2021 Aug;28(8):2367-2384
Cell death and differentiation 2021 Aug;28(8):2367-2384
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.
Yu Y, Zheng Q, Erramilli SK, Pan M, Park S, Xie Y, Li J, Fei J, Kossiakoff AA, Liu L, Zhao M
Nature chemical biology 2021 Aug;17(8):896-905
Nature chemical biology 2021 Aug;17(8):896-905
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
Xianjun F, Xirui X, Jie T, Huiwen M, Shaojun Z, Qiaoyun L, Yunxin L, Xuqun S
Journal of pharmacological sciences 2021 Aug;146(4):249-258
Journal of pharmacological sciences 2021 Aug;146(4):249-258
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
Zhu Q, Ma Y, Liang J, Wei Z, Li M, Zhang Y, Liu M, He H, Qu C, Cai J, Wang X, Zeng Y, Jiao Y
Signal transduction and targeted therapy 2021 Aug 9;6(1):299
Signal transduction and targeted therapy 2021 Aug 9;6(1):299
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Li J, Wang S, Wang N, Zheng Y, Yang B, Wang X, Zhang J, Pan B, Wang Z
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
Li J, Yan Z, Li H, Shi Q, Ahire V, Zhang S, Nimishetti N, Yang D, Allen TD, Zhang J
Journal of natural products 2021 Aug 27;84(8):2312-2320
Journal of natural products 2021 Aug 27;84(8):2312-2320
WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin.
Huang J, Liang Z, Guan C, Hua S, Jiang K
The Journal of cell biology 2021 Aug 2;220(8)
The Journal of cell biology 2021 Aug 2;220(8)
Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse.
Ma P, Li Y, Wang H, Mao B
Journal of molecular cell biology 2021 Aug 18;13(5):374-382
Journal of molecular cell biology 2021 Aug 18;13(5):374-382
CBL aggravates Ang II-induced cardiac hypertrophy via the VHL/HIF-1α pathway.
Yang Y, Zou P, He L, Shao J, Tang Y, Li J
Experimental cell research 2021 Aug 15;405(2):112730
Experimental cell research 2021 Aug 15;405(2):112730
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Adenosine A3 receptor activated in H2O2 oxidative stress of primary open-angle glaucoma.
Zhou Z, Gao Z, Yan W, Zhang Y, Huang J, Xiong K
Annals of translational medicine 2021 Apr;9(7):526
Annals of translational medicine 2021 Apr;9(7):526
Triterpene saponins from Guo-gang-long attenuate collagen-induced arthritis via regulating A20 and inhibiting MAPK pathway.
Xiong H, Luo M, Ju Y, Zhao Z, Zhang M, Xu R, Ren Y, Yang G, Mei Z
Journal of ethnopharmacology 2021 Apr 6;269:113707
Journal of ethnopharmacology 2021 Apr 6;269:113707
Human splenic TER cells: A relevant prognostic factor acting via the artemin-GFRα3-ERK pathway in pancreatic ductal adenocarcinoma.
Li TJ, Li H, Zhang WH, Xu SS, Jiang W, Li S, Gao HL, Han X, Xu HX, Wu CT, Wang WQ, Yu XJ, Liu L
International journal of cancer 2021 Apr 1;148(7):1756-1767
International journal of cancer 2021 Apr 1;148(7):1756-1767
Dnajb8, a target gene of SOX30, is dispensable for male fertility in mice.
Wang F, Kong S, Hu X, Li X, Xu B, Yue Q, Fu K, Ye L, Bai S
PeerJ 2020;8:e10582
PeerJ 2020;8:e10582
ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs.
Peng H, Guo Q, Xiao Y, Su T, Jiang TJ, Guo LJ, Wang M
Frontiers in cell and developmental biology 2020;8:872
Frontiers in cell and developmental biology 2020;8:872
An MRTF-A-Sp1-PDE5 Axis Mediates Angiotensin-II-Induced Cardiomyocyte Hypertrophy.
Wu T, Wang H, Xin X, Yang J, Hou Y, Fang M, Lu X, Xu Y
Frontiers in cell and developmental biology 2020;8:839
Frontiers in cell and developmental biology 2020;8:839
Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.
Wu QW, Kapfhammer JP
Frontiers in cell and developmental biology 2020;8:569889
Frontiers in cell and developmental biology 2020;8:569889
PCDH7 Inhibits the Formation of Homotypic Cell-in-Cell Structure.
Wang C, Chen A, Ruan B, Niu Z, Su Y, Qin H, Zheng Y, Zhang B, Gao L, Chen Z, Huang H, Wang X, Sun Q
Frontiers in cell and developmental biology 2020;8:329
Frontiers in cell and developmental biology 2020;8:329
RGS12 is required for the maintenance of mitochondrial function during skeletal development.
Yuan G, Yang S, Liu M, Yang S
Cell discovery 2020;6:59
Cell discovery 2020;6:59
Glutamine protects intestine against ischemia-reperfusion injury by alleviating endoplasmic reticulum stress induced apoptosis in rats.
Xu H, Liu G, Gu H, Wang J, Li Y
Acta cirurgica brasileira 2020;35(1):e202000104
Acta cirurgica brasileira 2020;35(1):e202000104
Ambroxol Improves Neuronal Survival and Reduces White Matter Damage through Suppressing Endoplasmic Reticulum Stress in Microglia after Intracerebral Hemorrhage.
Jiang X, Zhang J, Kou B, Zhang C, Zhong J, Fang X, Huang X, Zhang X, Xie F, Hu Q, Ge H, Yu A
BioMed research international 2020;2020:8131286
BioMed research international 2020;2020:8131286
Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation.
Li L, Zheng W, Wang C, Qi J, Li H
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7826874
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7826874
MicroRNA-384 Inhibits the Progression of Papillary Thyroid Cancer by Targeting PRKACB.
Wang Y, Wang B, Zhou H, Zhang X, Qian X, Cui J
BioMed research international 2020;2020:4983420
BioMed research international 2020;2020:4983420
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Du J, Ren W, Zhang Q, Fu N, Han F, Cui P, Li W, Kong L, Zhao S, Wang R, Zhang Y, Yang L, Kong L, Nan Y
BioMed research international 2020;2020:4910601
BioMed research international 2020;2020:4910601
Wnt5a/CaMKII/ERK/CCL2 axis is required for tumor-associated macrophages to promote colorectal cancer progression.
Liu Q, Song J, Pan Y, Shi D, Yang C, Wang S, Xiong B
International journal of biological sciences 2020;16(6):1023-1034
International journal of biological sciences 2020;16(6):1023-1034
MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor.
Wang N, He L, Lin H, Tan L, Sun Y, Zhang X, Danser AHJ, Lu HS, He Y, Lu X
PloS one 2020;15(5):e0225356
PloS one 2020;15(5):e0225356
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Luo J, Luo X, Liu X, Fang Z, Xu J, Li L
OncoTargets and therapy 2020;13:1321-1330
OncoTargets and therapy 2020;13:1321-1330
Kaempferol attenuated cisplatin-induced cardiac injury via inhibiting STING/NF-κB-mediated inflammation.
Qi Y, Ying Y, Zou J, Fang Q, Yuan X, Cao Y, Cai Y, Fu S
American journal of translational research 2020;12(12):8007-8018
American journal of translational research 2020;12(12):8007-8018
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway.
Zhang R, Han D, Li L, Luo W, Liu J, Qian L
Cancer management and research 2020;12:9539-9549
Cancer management and research 2020;12:9539-9549
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma.
Xu Q, Chang H, Tian X, Lou C, Ma H, Yang X
Journal of Cancer 2020;11(6):1596-1605
Journal of Cancer 2020;11(6):1596-1605
Phosphoribosyl pyrophosphate synthetases 2 knockdown inhibits prostate cancer progression by suppressing cell cycle and inducing cell apoptosis.
Qiao H, Tan X, Lv DJ, Xing RW, Shu FP, Zhong CF, Li C, Zou YG, Mao XM
Journal of Cancer 2020;11(5):1027-1037
Journal of Cancer 2020;11(5):1027-1037
Overexpression of KIAA0101 Promotes the Progression of Non-small Cell Lung Cancer.
Cao H, Zheng J, Yao Y, Yang Q, Yan R, Sun W, Ruan K, Zhou J, Zhou J
Journal of Cancer 2020;11(22):6663-6674
Journal of Cancer 2020;11(22):6663-6674
Inward Tension of Talin and Integrin-related Osmotic Pressure are involved Synergetically in the Invasion and Metastasis of Non-small Cell Lung Cancer.
Song Y, Li C, Fu Y, Xie Q, Guo J, Li G, Wu H
Journal of Cancer 2020;11(17):5032-5041
Journal of Cancer 2020;11(17):5032-5041
High-Intensity Interval Training Restores Glycolipid Metabolism and Mitochondrial Function in Skeletal Muscle of Mice With Type 2 Diabetes.
Zheng L, Rao Z, Guo Y, Chen P, Xiao W
Frontiers in endocrinology 2020;11:561
Frontiers in endocrinology 2020;11:561
Coxsackievirus A6 Induces Necroptosis for Viral Production.
Zhang S, Yu X, Meng X, Huo W, Su Y, Liu J, Liu Y, Zhang J, Wang S, Yu J
Frontiers in microbiology 2020;11:42
Frontiers in microbiology 2020;11:42
Establishment of cell lines with porcine spermatogonial stem cell properties.
Zheng Y, Feng T, Zhang P, Lei P, Li F, Zeng W
Journal of animal science and biotechnology 2020;11:33
Journal of animal science and biotechnology 2020;11:33
Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription.
Chen DQ, Wu XQ, Chen L, Hu HH, Wang YN, Zhao YY
Therapeutic advances in chronic disease 2020;11:2040622320962648
Therapeutic advances in chronic disease 2020;11:2040622320962648
SYTL4 downregulates microtubule stability and confers paclitaxel resistance in triple-negative breast cancer.
Liu XY, Jiang W, Ma D, Ge LP, Yang YS, Gou ZC, Xu XE, Shao ZM, Jiang YZ
Theranostics 2020;10(24):10940-10956
Theranostics 2020;10(24):10940-10956
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Zhang Y, Wang S, Zhang L, Zhou F, Zhu K, Zhu Q, Liu Q, Liu Y, Jiang L, Ning G, Bi Y, Zhou L, Wang X
Theranostics 2020;10(16):7351-7368
Theranostics 2020;10(16):7351-7368
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, Yan J, Wang L, Ye H, Jiao S, Xiang R, Shi Y
Theranostics 2020;10(15):6839-6853
Theranostics 2020;10(15):6839-6853
A Prognostic Prediction Model Developed Based on Four CpG Sites and Weighted Correlation Network Analysis Identified DNAJB1 as a Novel Biomarker for Pancreatic Cancer.
Kong L, Liu P, Fei X, Wu T, Wang Z, Zhang B, Li J, Tan X
Frontiers in oncology 2020;10:1716
Frontiers in oncology 2020;10:1716
SYPL1 Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma via Suppression of ROS-Induced ERK Activation.
Song Y, Sun X, Duan F, He C, Wu J, Huang X, Xing K, Sun S, Wang R, Xie F, Mao Y, Wang J, Li S
Frontiers in oncology 2020;10:1482
Frontiers in oncology 2020;10:1482
Caspase-3 inhibitor inhibits enterovirus D68 production.
Huo W, Yu J, Liu C, Wu T, Wang Y, Meng X, Song F, Zhang S, Su Y, Liu Y, Liu J, Yu X, Hua S
Journal of microbiology (Seoul, Korea) 2020 Sep;58(9):812-820
Journal of microbiology (Seoul, Korea) 2020 Sep;58(9):812-820
The chromatin remodeler Brg1 is required for formation and maintenance of hematopoietic stem cells.
Tu J, Liu X, Jia H, Reilly J, Yu S, Cai C, Liu F, Lv Y, Huang Y, Lu Z, Han S, Jiang T, Shu X, Wu X, Tang Z, Lu Q, Liu M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11997-12008
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11997-12008
Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.
Centa JL, Jodelka FM, Hinrich AJ, Johnson TB, Ochaba J, Jackson M, Duelli DM, Weimer JM, Rigo F, Hastings ML
Nature medicine 2020 Sep;26(9):1444-1451
Nature medicine 2020 Sep;26(9):1444-1451
Dependence of PINK1 accumulation on mitochondrial redox system.
Gao F, Zhang Y, Hou X, Tao Z, Ren H, Wang G
Aging cell 2020 Sep;19(9):e13211
Aging cell 2020 Sep;19(9):e13211
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Yang Y, Wang Q, Song D, Zen R, Zhang L, Wang Y, Yang H, Zhang D, Jia J, Zhang J, Wang J
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Comprehensive lipidomics in apoM-/- mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation.
Shi Y, Lam SM, Liu H, Luo G, Zhang J, Yao S, Li J, Zheng L, Xu N, Zhang X, Shui G
Journal of genetics and genomics = Yi chuan xue bao 2020 Sep 20;47(9):523-534
Journal of genetics and genomics = Yi chuan xue bao 2020 Sep 20;47(9):523-534
Metformin improves boar sperm quality via 5'-AMP-activated protein kinase-mediated energy metabolism in vitro.
Li RN, Zhu ZD, Zheng Y, Lv YH, Tian XE, Wu, Wang YJ, Zeng WX
Zoological research 2020 Sep 18;41(5):527-538
Zoological research 2020 Sep 18;41(5):527-538
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Xu J, Zhang Y, You S, Guo Y, Chen S, Chang Y, Zhang N, Sun Y
Life sciences 2020 Sep 15;257:118053
Life sciences 2020 Sep 15;257:118053
Consumption of a Blueberry-Enriched Diet by Women for 6 Weeks Alters Determinants of Human Muscle Progenitor Cell Function.
Blum JE, Gheller BJ, Hwang S, Bender E, Gheller M, Thalacker-Mercer AE
The Journal of nutrition 2020 Sep 1;150(9):2412-2418
The Journal of nutrition 2020 Sep 1;150(9):2412-2418
Proline Protects Boar Sperm against Oxidative Stress through Proline Dehydrogenase-Mediated Metabolism and the Amine Structure of Pyrrolidine.
Feng C, Zhu Z, Bai W, Li R, Zheng Y, Tian X, Wu, Lu H, Wang Y, Zeng W
Animals : an open access journal from MDPI 2020 Sep 1;10(9)
Animals : an open access journal from MDPI 2020 Sep 1;10(9)
NQO1-selective activated prodrugs of combretastatin A-4: Synthesis and biological evaluation.
Zhang C, Qu Y, Ma X, Li M, Li S, Li Y, Wu L
Bioorganic chemistry 2020 Oct;103:104200
Bioorganic chemistry 2020 Oct;103:104200
SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation.
Li S, Zhang Y, Guan Z, Li H, Ye M, Chen X, Shen J, Zhou Y, Shi ZL, Zhou P, Peng K
Signal transduction and targeted therapy 2020 Oct 9;5(1):235
Signal transduction and targeted therapy 2020 Oct 9;5(1):235
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Li C, Deng C, Pan G, Wang X, Zhang K, Dong Z, Zhao G, Tan M, Hu X, Shi S, Du J, Ji H, Wang X, Yang L, Cui H
Journal of experimental & clinical cancer research : CR 2020 Oct 30;39(1):230
Journal of experimental & clinical cancer research : CR 2020 Oct 30;39(1):230
Broad-complex transcription factor mediates opposing hormonal regulation of two phylogenetically distant arginine kinase genes in Tribolium castaneum.
Zhang N, Jiang H, Meng X, Qian K, Liu Y, Song Q, Stanley D, Wu J, Park Y, Wang J
Communications biology 2020 Oct 30;3(1):631
Communications biology 2020 Oct 30;3(1):631
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level.
Huang D, Xiao F, Hao H, Hua F, Luo Z, Huang Z, Li Q, Chen S, Cheng X, Zhang X, Fang W, Hu X, Liu F
Cell communication and signaling : CCS 2020 Oct 27;18(1):169
Cell communication and signaling : CCS 2020 Oct 27;18(1):169
HOXA13 promotes colon cancer progression through β-catenin-dependent WNT pathway.
Gu Y, Gu J, Shen K, Zhou H, Hao J, Li F, Yu H, Chen Y, Li J, Li Y, Liang H, Dong Y
Experimental cell research 2020 Oct 15;395(2):112238
Experimental cell research 2020 Oct 15;395(2):112238
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Hao J, Song Y, Tian B, Qi C, Li L, Wang L, Xing Y, Zhao X, Liu J
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells.
Zhou Y, Wang Y, Wu S, Yan Y, Hu Y, Zheng Z, Li J, Wu W
Cell death & disease 2020 Oct 1;11(9):819
Cell death & disease 2020 Oct 1;11(9):819
Anti-inflammatory and analgesic activities of indigo through regulating the IKKβ/IκB/NF-κB pathway in mice.
Liu N, Zhang GX, Niu YT, Wang Q, Zheng J, Yang JM, Sun T, Niu JG, Yu JQ
Food & function 2020 Oct 1;11(10):8537-8546
Food & function 2020 Oct 1;11(10):8537-8546
Atractyloside targets cancer-associated fibroblasts and inhibits the metastasis of colon cancer.
Qi L, Song F, Han Y, Zhang Y, Ding Y
Annals of translational medicine 2020 Nov;8(21):1443
Annals of translational medicine 2020 Nov;8(21):1443
Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status.
Ohno Y, Satoh K, Shitara A, Into T, Kashimata M
The Journal of physiology 2020 Nov;598(21):4907-4925
The Journal of physiology 2020 Nov;598(21):4907-4925
Elevated miR-124-3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T-synthase.
Huang L, Sun TY, Hu LJ, Hu SL, Sun HM, Zhao FQ, Wu B, Yang S, Ji FQ, Zhou DS
Aging cell 2020 Nov;19(11):e13252
Aging cell 2020 Nov;19(11):e13252
Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.
Mabbitt PD, Loreto A, Déry MA, Fletcher AJ, Stanley M, Pao KC, Wood NT, Coleman MP, Virdee S
Nature chemical biology 2020 Nov;16(11):1227-1236
Nature chemical biology 2020 Nov;16(11):1227-1236
Melatonin Rescues the Ti Particle-Impaired Osteogenic Potential of Bone Marrow Mesenchymal Stem Cells via the SIRT1/SOD2 Signaling Pathway.
Zhang Y, Zhu X, Wang G, Chen L, Yang H, He F, Lin J
Calcified tissue international 2020 Nov;107(5):474-488
Calcified tissue international 2020 Nov;107(5):474-488
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.
Zhang Z, Wang Y, Shan Y, Zhou R, Yin W
Scientific reports 2020 Nov 6;10(1):19272
Scientific reports 2020 Nov 6;10(1):19272
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Zhang Z, Wang Y, Shan Y, Yin W
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury.
Ying X, Xie Q, Li S, Yu X, Zhou K, Yue J, Chen X, Tu W, Yang G, Jiang S
Fluids and barriers of the CNS 2020 Nov 25;17(1):70
Fluids and barriers of the CNS 2020 Nov 25;17(1):70
Cell Signaling Coordinates Global PRC2 Recruitment and Developmental Gene Expression in Murine Embryonic Stem Cells.
Aljazi MB, Gao Y, Wu Y, Mias GI, He J
iScience 2020 Nov 20;23(11):101646
iScience 2020 Nov 20;23(11):101646
The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs.
Huang B, He Y, Li S, Wei X, Liu J, Shan Z, Huang Y, Chen J, Zhao F
Experimental & molecular medicine 2020 May;52(5):865-875
Experimental & molecular medicine 2020 May;52(5):865-875
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Luo W, Zhang H, Liang X, Xia R, Deng H, Yi Q, Lv L, Qian L
Oncology reports 2020 May;43(5):1692-1704
Oncology reports 2020 May;43(5):1692-1704
Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca2+/CaMKII/CREB signaling pathway.
Chen C, Xu D, Zhang ZH, Jia SZ, Cao XC, Chen YB, Song GL, Wong MS, Li HW
Experimental neurology 2020 May;327:113210
Experimental neurology 2020 May;327:113210
MKL1 mediates TGF-β-induced CTGF transcription to promote renal fibrosis.
Mao L, Liu L, Zhang T, Wu X, Zhang T, Xu Y
Journal of cellular physiology 2020 May;235(5):4790-4803
Journal of cellular physiology 2020 May;235(5):4790-4803
Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin.
Zeng Y, Hua YQ, Wang W, Zhang H, Xu XL
Biochemical pharmacology 2020 May;175:113927
Biochemical pharmacology 2020 May;175:113927
The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair.
Huang T, Yuan S, Gao L, Li M, Yu X, Zhan J, Yin Y, Liu C, Zhang C, Lu G, Li W, Liu J, Chen ZJ, Liu H
eLife 2020 May 6;9
eLife 2020 May 6;9
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
Li Y, Tang L, Yue J, Gou X, Lin A, Weatherbee SD, Wu X
EMBO reports 2020 May 6;21(5):e48566
EMBO reports 2020 May 6;21(5):e48566
GDF15 knockdown promotes erastin-induced ferroptosis by decreasing SLC7A11 expression.
Chen L, Qiao L, Bian Y, Sun X
Biochemical and biophysical research communications 2020 May 28;526(2):293-299
Biochemical and biophysical research communications 2020 May 28;526(2):293-299
Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia.
Fujiwara-Tani R, Fujii K, Mori S, Kishi S, Sasaki T, Ohmori H, Nakashima C, Kawahara I, Nishiguchi Y, Mori T, Sho M, Kondoh M, Luo Y, Kuniyasu H
International journal of molecular sciences 2020 May 28;21(11)
International journal of molecular sciences 2020 May 28;21(11)
Second-order optimized regularized structured illumination microscopy (sorSIM) for high-quality and rapid super resolution image reconstruction with low signal level.
Yu W, Li Y, Jooken S, Deschaume O, Liu F, Wang S, Bartic C
Optics express 2020 May 25;28(11):16708-16724
Optics express 2020 May 25;28(11):16708-16724
Autophagy suppression of trophoblast cells induces pregnancy loss by activating decidual NK cytotoxicity and inhibiting trophoblast invasion.
Tan HX, Yang SL, Li MQ, Wang HY
Cell communication and signaling : CCS 2020 May 12;18(1):73
Cell communication and signaling : CCS 2020 May 12;18(1):73
PIM1 inhibitor synergizes the anti-tumor effect of osimertinib via STAT3 dephosphorylation in EGFR-mutant non-small cell lung cancer.
Sun Z, Zeng L, Zhang M, Zhang Y, Yang N
Annals of translational medicine 2020 Mar;8(6):366
Annals of translational medicine 2020 Mar;8(6):366
Ophiopogonin D promotes bone regeneration by stimulating CD31hi EMCNhi vessel formation.
Yang M, Li CJ, Xiao Y, Guo Q, Huang Y, Su T, Luo XH, Jiang TJ
Cell proliferation 2020 Mar;53(3):e12784
Cell proliferation 2020 Mar;53(3):e12784
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Li C, Liu F, Liu S, Pan H, Du H, Huang J, Xie Y, Li Y, Zhao R, Wei Y
EBioMedicine 2020 Mar;53:102695
EBioMedicine 2020 Mar;53:102695
Inhibition of UCHL1 by LDN-57444 attenuates Ang II-Induced atrial fibrillation in mice.
Bi HL, Zhang YL, Yang J, Shu Q, Yang XL, Yan X, Chen C, Li Z, Li HH
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Mar;43(3):168-177
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Mar;43(3):168-177
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Ren Y, Xu X, Mao CY, Han KK, Xu YJ, Cao BY, Zhang ZB, Sethi G, Tang XW, Mao XL
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
Kimura Y, Yanagida T, Onda A, Tsukui D, Hosoyamada M, Kono H
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):570-582
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):570-582
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
Qi M, Dai D, Liu J, Li Z, Liang P, Wang Y, Cheng L, Zhan Y, An Z, Song Y, Yang Y, Yan X, Xiao H, Shao H
Oncogene 2020 Mar;39(13):2707-2723
Oncogene 2020 Mar;39(13):2707-2723
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCFβ-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer.
Yang Q, Li K, Huang X, Zhao C, Mei Y, Li X, Jiao L, Yang H
Molecular therapy. Nucleic acids 2020 Mar 6;19:974-985
Molecular therapy. Nucleic acids 2020 Mar 6;19:974-985
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Liu Q, Yang C, Wang S, Shi D, Wei C, Song J, Lin X, Dou R, Bai J, Xiang Z, Huang S, Liu K, Xiong B
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development.
Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ
Development (Cambridge, England) 2020 Mar 30;147(6)
Development (Cambridge, England) 2020 Mar 30;147(6)
MACF1 promotes preosteoblast migration by mediating focal adhesion turnover through EB1.
Su P, Yin C, Li D, Yang C, Wang X, Pei J, Tian Y, Qian A
Biology open 2020 Mar 24;9(3)
Biology open 2020 Mar 24;9(3)
Dietary Supplemented Curcumin Improves Meat Quality and Antioxidant Status of Intrauterine Growth Retardation Growing Pigs via Nrf2 Signal Pathway.
Zhang L, Zhang J, Yan E, He J, Zhong X, Zhang L, Wang C, Wang T
Animals : an open access journal from MDPI 2020 Mar 24;10(3)
Animals : an open access journal from MDPI 2020 Mar 24;10(3)
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Guo Y, Jia P, Chen Y, Yu H, Xin X, Bao Y, Yang H, Wu N, Sun Y, Jia D
Life sciences 2020 Mar 15;245:117347
Life sciences 2020 Mar 15;245:117347
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
Zhang J, Yang J, Yang N, Ma J, Lu D, Dong Y, Liang H, Liu D, Cang M
Lipids in health and disease 2020 Mar 13;19(1):39
Lipids in health and disease 2020 Mar 13;19(1):39
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
Zeng ZM, Du HY, Xiong L, Zeng XL, Zhang P, Cai J, Huang L, Liu AW
Life sciences 2020 Mar 1;244:117342
Life sciences 2020 Mar 1;244:117342
AFF1 inhibits adipogenic differentiation via targeting TGM2 transcription.
Chen Y, Wang Y, Lin W, Sheng R, Wu Y, Xu R, Zhou C, Yuan Q
Cell proliferation 2020 Jun;53(6):e12831
Cell proliferation 2020 Jun;53(6):e12831
Proanthocyanidins Promote Osteogenic Differentiation of Human Periodontal Ligament Fibroblasts in Inflammatory Environment Via Suppressing NF-κB Signal Pathway.
Huang J, Liu L, Jin S, Zhang Y, Zhang L, Li S, Song A, Yang P
Inflammation 2020 Jun;43(3):892-902
Inflammation 2020 Jun;43(3):892-902
Transient inhibition of rDNA transcription in donor cells improves ribosome biogenesis and preimplantation development of embryos derived from somatic cell nuclear transfer.
Liao C, Pang N, Liu Z, Lei L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8283-8295
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8283-8295
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
Dana H, Bayramov KK, Delibaşı N, Tahtasakal R, Bayramov R, Hamurcu Z, Sener EF
Neuromolecular medicine 2020 Jun;22(2):239-249
Neuromolecular medicine 2020 Jun;22(2):239-249
Ophiocordyceps lanpingensis polysaccharides attenuate pulmonary fibrosis in mice.
Zhou S, Zhou Y, Yu J, Du Y, Tan Y, Ke Y, Wang J, Han B, Ge F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110058
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110058
Downregulated miR-150 in bone marrow mesenchymal stem cells attenuates the apoptosis of LPS-stimulated RAW264.7 via MTCH2-dependent mitochondria transfer.
Zhou X, Zhang K, He Z, Deng Y, Gao Y
Biochemical and biophysical research communications 2020 Jun 4;526(3):560-567
Biochemical and biophysical research communications 2020 Jun 4;526(3):560-567
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.
Qiao X, van der Zanden SY, Wander DPA, Borràs DM, Song JY, Li X, van Duikeren S, van Gils N, Rutten A, van Herwaarden T, van Tellingen O, Giacomelli E, Bellin M, Orlova V, Tertoolen LGJ, Gerhardt S, Akkermans JJ, Bakker JM, Zuur CL, Pang B, Smits AM, Mummery CL, Smit L, Arens R, Li J, Overkleeft HS, Neefjes J
Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 30;117(26):15182-15192
Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 30;117(26):15182-15192
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
Lei Q, Yi T, Li H, Yan Z, Lv Z, Li G, Wang Y
Scientific reports 2020 Jun 30;10(1):10604
Scientific reports 2020 Jun 30;10(1):10604
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Tang D, Liu X, Chen K, Li Z, Dai Y, Xu J, Zhang HT, Gao X, Liu L
Aging 2020 Jun 27;12(13):13297-13317
Aging 2020 Jun 27;12(13):13297-13317
Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis.
Guo Q, Bi D, Wu M, Yu B, Hu L, Liu C, Gu L, Zhu H, Lei A, Xu X, Wang J
BMC microbiology 2020 Jun 19;20(1):171
BMC microbiology 2020 Jun 19;20(1):171
Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages.
Zhang C, Zhao C, Chen X, Tao R, Wang S, Meng G, Liu X, Shao C, Su X
Cell death & disease 2020 Jun 18;11(6):470
Cell death & disease 2020 Jun 18;11(6):470
Fine particulate matter increases airway hyperresponsiveness through kallikrein-bradykinin pathway.
Cao X, Wang M, Li J, Luo Y, Li R, Yan X, Zhang H
Ecotoxicology and environmental safety 2020 Jun 1;195:110491
Ecotoxicology and environmental safety 2020 Jun 1;195:110491
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
Deng M, Tan J, Hu C, Hou T, Peng W, Liu J, Yu B, Dai Q, Zhou J, Yang Y, Dong R, Ruan C, Dong S, Xu J
Advanced healthcare materials 2020 Jul;9(13):e2000353
Advanced healthcare materials 2020 Jul;9(13):e2000353
Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis.
Chen DQ, Wang YN, Vaziri ND, Chen L, Hu HH, Zhao YY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153232
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153232
Expression and significance of T-cell immunoglobulin mucin molecule 3 and its ligand galectin-9 in patients with adenomyosis.
Huang P, Lv C, Zhang C, Feng H, Li C, Zhang H, Zhao X, Li M
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Jul;36(7):605-610
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Jul;36(7):605-610
EHF promotes colorectal carcinoma progression by activating TGF-β1 transcription and canonical TGF-β signaling.
Wang L, Ai M, Nie M, Zhao L, Deng G, Hu S, Han Y, Zeng W, Wang Y, Yang M, Wang S
Cancer science 2020 Jul;111(7):2310-2324
Cancer science 2020 Jul;111(7):2310-2324
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
Liu B, Xiao J, Dong M, Qiu Z, Jin J
Cancer science 2020 Jul;111(7):2259-2274
Cancer science 2020 Jul;111(7):2259-2274
RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation.
Chen C, Liu C, Niu Z, Li M, Zhang Y, Gao R, Chen H, Wang Q, Zhang S, Zhou R, Gan L, Zhang Z, Zhu T, Yu H, Liu J
Aging 2020 Jul 21;12(14):14490-14505
Aging 2020 Jul 21;12(14):14490-14505
Clinically relevant high levels of human C-reactive protein induces endothelial dysfunction and hypertension by inhibiting the AMPK-eNOS axis.
Cheng L, Wang L, Guo M, He J, Deng Y, Liu J, Wei Y, Wang C, Zhou J, Ma L, Song Q, Yuan Z, Wu Y
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1805-1819
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1805-1819
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Hu X, Wang L, Wang Y, Ji J, Li J, Wang Z, Li C, Zhang Y, Zhang ZR
Molecular cell 2020 Jul 16;79(2):320-331.e9
Molecular cell 2020 Jul 16;79(2):320-331.e9
Downregulation of the circadian rhythm regulator HLF promotes multiple-organ distant metastases in non-small cell lung cancer through PPAR/NF-κb signaling.
Chen J, Liu A, Lin Z, Wang B, Chai X, Chen S, Lu W, Zheng M, Cao T, Zhong M, Li R, Wu M, Lu Z, Pang W, Huang W, Xiao L, Lin D, Wang Z, Lei F, Chen X, Long W, Zheng Y, Chen Q, Zeng J, Ren D, Li J, Zhang X, Huang Y
Cancer letters 2020 Jul 10;482:56-71
Cancer letters 2020 Jul 10;482:56-71
Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation.
Zhang L, Ye M, Zhu L, Cha J, Li C, Yao YG, Mao B
Cells 2020 Jul 1;9(7)
Cells 2020 Jul 1;9(7)
Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.
Li S, Li XY, Zhang TJ, Kamara MO, Liang JW, Zhu J, Meng FH
Bioorganic chemistry 2020 Jan;94:103385
Bioorganic chemistry 2020 Jan;94:103385
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Liang Y, Hou L, Li L, Li L, Zhu L, Wang Y, Huang X, Hou Y, Zhu D, Zou H, Gu Y, Weng X, Wang Y, Li Y, Wu T, Yao M, Gross I, Gaiddon C, Luo M, Wang J, Meng X
Oncogene 2020 Jan;39(2):469-485
Oncogene 2020 Jan;39(2):469-485
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Deng J, Xu T, Yang J, Zhang KM, Li Q, Yu XY, Li R, Fu J, Jiang Q, Ma JX, Chen YM
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
Poly (ADP-ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation-associated chemotherapy-induced autophagy in leukaemia cells.
Li Y, Xie J, Li X, Fang J
Oncology letters 2020 Jan;19(1):368-378
Oncology letters 2020 Jan;19(1):368-378
Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition.
Denu RA, Kaur G, Sass MM, Lakkaraju A, Burkard ME
Molecular cancer research : MCR 2020 Jan;18(1):33-45
Molecular cancer research : MCR 2020 Jan;18(1):33-45
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Xiao H, Sun X, Liu R, Chen Z, Lin Z, Yang Y, Zhang M, Liu P, Quan S, Huang H
Pharmacological research 2020 Jan;151:104559
Pharmacological research 2020 Jan;151:104559
Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.
Zhu Y, Shi F, Wang M, Ding J
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820915958
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820915958
MicroRNA-547-5p-mediated interleukin-33/suppressor of tumorigenicity 2 signaling underlies the genesis and maintenance of neuropathic pain and is targeted by the therapy with bone marrow stromal cells.
Zhou J, Zhuang T, Ma P, Shan L, Sun XD, Gong S, Tao J, Yu XM, Jiang X
Molecular pain 2020 Jan-Dec;16:1744806920931737
Molecular pain 2020 Jan-Dec;16:1744806920931737
CXCL12/CXCR4 signaling induced itch and pain sensation in a murine model of allergic contact dermatitis.
Su W, Yu J, Liu Q, Ma L, Huang Y
Molecular pain 2020 Jan-Dec;16:1744806920926426
Molecular pain 2020 Jan-Dec;16:1744806920926426
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Bai Z, Liu X, Guan Q, Ding N, Wei Q, Tong B, Zhao M, Zhang W, Ma L
Chemico-biological interactions 2020 Jan 5;315:108886
Chemico-biological interactions 2020 Jan 5;315:108886
The Capsid Protein of Semliki Forest Virus Antagonizes RNA Interference in Mammalian Cells.
Qian Q, Zhou H, Shu T, Mu J, Fang Y, Xu J, Li T, Kong J, Qiu Y, Zhou X
Journal of virology 2020 Jan 17;94(3)
Journal of virology 2020 Jan 17;94(3)
Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.
Cheng Y, Sun F, Li S, Gao M, Wang L, Sarhan M, Abdel-Rahman MA, Li W, Kwok HF, Wu Y, Cao Z
Antibiotics (Basel, Switzerland) 2020 Jan 17;9(1)
Antibiotics (Basel, Switzerland) 2020 Jan 17;9(1)
Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer letters 2020 Jan 1;468:27-40
Cancer letters 2020 Jan 1;468:27-40
ING4 alleviated lipopolysaccharide-induced inflammation by regulating the NF-κB pathway via a direct interaction with SIRT1.
Yang Y, Liu Y, He X, Yang F, Han S, Qin A, Wu G, Liu M, Li Z, Wang J, Yang X, Hu D
Immunology and cell biology 2020 Feb;98(2):127-137
Immunology and cell biology 2020 Feb;98(2):127-137
Biallelic mutation of HSD17B4 induces middle age-onset spinocerebellar ataxia.
Matsuda Y, Morino H, Miyamoto R, Kurashige T, Kume K, Mizuno N, Kanaya Y, Tada Y, Ohsawa R, Yokota K, Shimozawa N, Maruyama H, Kawakami H
Neurology. Genetics 2020 Feb;6(1):e396
Neurology. Genetics 2020 Feb;6(1):e396
Functional analysis of natural PCSK9 mutants in modern and archaic humans.
Mikaeeli S, Susan-Resiga D, Girard E, Ben Djoudi Ouadda A, Day R, Prost S, Seidah NG
The FEBS journal 2020 Feb;287(3):515-528
The FEBS journal 2020 Feb;287(3):515-528
Expanding the retinal phenotype of RP1: from retinitis pigmentosa to a novel and singular macular dystrophy.
Riera M, Abad-Morales V, Navarro R, Ruiz-Nogales S, Méndez-Vendrell P, Corcostegui B, Pomares E
The British journal of ophthalmology 2020 Feb;104(2):173-181
The British journal of ophthalmology 2020 Feb;104(2):173-181
The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets.
Zachari M, Rainard JM, Pandarakalam GC, Robinson L, Gillespie J, Rajamanickam M, Hamon V, Morrison A, Ganley IG, McElroy SP
The Biochemical journal 2020 Feb 28;477(4):801-814
The Biochemical journal 2020 Feb 28;477(4):801-814
Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).
Zhao Y, Lei Y, He SW, Li YQ, Wang YQ, Hong XH, Liang YL, Li JY, Chen Y, Luo WJ, Zhang PP, Yang XJ, He QM, Ma J, Liu N, Tang LL
Cells 2020 Feb 27;9(3)
Cells 2020 Feb 27;9(3)
Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.
Liu H, Yang H, Fang Y, Li K, Tian L, Liu X, Zhang W, Tan Y, Lai W, Bian L, Lin B, Xi Z
The Science of the total environment 2020 Feb 25;705:135809
The Science of the total environment 2020 Feb 25;705:135809
WDR62 is a novel participator in spindle migration and asymmetric cytokinesis during mouse oocyte meiotic maturation.
Wang YS, Jiao XF, Chen F, Wu D, Ding ZM, Miao YL, Huo LJ
Experimental cell research 2020 Feb 1;387(1):111773
Experimental cell research 2020 Feb 1;387(1):111773
Bnip3 mediates doxorubicin-induced cardiomyocyte pyroptosis via caspase-3/GSDME.
Zheng X, Zhong T, Ma Y, Wan X, Qin A, Yao B, Zou H, Song Y, Yin D
Life sciences 2020 Feb 1;242:117186
Life sciences 2020 Feb 1;242:117186
Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation.
Wang M, Hu HH, Chen YY, Chen L, Wu XQ, Zhao YY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Dec;79:153323
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Dec;79:153323
Asiaticoside Inhibits Neuronal Apoptosis and Promotes Functional Recovery After Spinal Cord Injury in Rats.
Fan L, Li X, Liu T
Journal of molecular neuroscience : MN 2020 Dec;70(12):1988-1996
Journal of molecular neuroscience : MN 2020 Dec;70(12):1988-1996
Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol transport.
Andersen JP, Zhang J, Sun H, Liu X, Liu J, Nie J, Shi Y
Molecular metabolism 2020 Dec;42:101055
Molecular metabolism 2020 Dec;42:101055
ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin-3 and NRXN3.
Zhao Y, Hong XH, Li K, Li YQ, Li YQ, He SW, Zhang PP, Li JY, Li Q, Liang YL, Chen Y, Ma J, Liu N, Chen YP
Cancer communications (London, England) 2020 Dec;40(12):721-737
Cancer communications (London, England) 2020 Dec;40(12):721-737
Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists.
Qin J, Liu J, Wu C, Xu J, Tang B, Guo K, Chen X, Liu W, Wu T, Zhou H, Fang M, Wu Z
Journal of enzyme inhibition and medicinal chemistry 2020 Dec;35(1):880-896
Journal of enzyme inhibition and medicinal chemistry 2020 Dec;35(1):880-896
EBV-miR-BART12 accelerates migration and invasion in EBV-associated cancer cells by targeting tubulin polymerization-promoting protein 1.
Wu Y, Wang D, Wei F, Xiong F, Zhang S, Gong Z, Shi L, Li X, Xiang B, Ma J, Deng H, He Y, Liao Q, Zhang W, Li X, Li Y, Guo C, Zeng Z, Li G, Xiong W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16205-16223
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16205-16223
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
He X, Li M, Yu H, Liu G, Wang N, Yin C, Tu Q, Narla G, Tao Y, Cheng S, Yin H
PLoS biology 2020 Dec;18(12):e3000803
PLoS biology 2020 Dec;18(12):e3000803
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Li Y, Bai L, Yu H, Cai D, Wang X, Huang B, Peng S, Huang M, Cao G, Kaz AM, Grady WM, Wang J, Luo Y
Cancer research 2020 Dec 1;80(23):5203-5215
Cancer research 2020 Dec 1;80(23):5203-5215
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Liu H, Tang D, Zhou X, Yang X, Chen AF
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495
Macrophage-stimulating activity of European eel (Anguilla anguilla) peptides in RAW264.7 cells mediated via NF-κB and MAPK signaling pathways.
Yao L, Yang P, Luo W, Li S, Wu Y, Cai N, Bi D, Li H, Han Q, Xu X
Food & function 2020 Dec 1;11(12):10968-10978
Food & function 2020 Dec 1;11(12):10968-10978
Naked antisense double-stranded DNA oligonucleotide efficiently suppresses BCR-ABL positive leukemic cells.
Hoshiko T, Kubota Y, Akisawa T, Watanabe T, Tanigawara K, Yano J, Kimura S
Investigational new drugs 2020 Aug;38(4):1012-1019
Investigational new drugs 2020 Aug;38(4):1012-1019
Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress.
Liu Y, Zou GJ, Tu BX, Hu ZL, Luo C, Cui YH, Xu Y, Li F, Dai RP, Bi FF, Li CQ
Neurotoxicity research 2020 Aug;38(2):370-384
Neurotoxicity research 2020 Aug;38(2):370-384
Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer.
Huang Y, Xiang Y, Xie Z, Cai Y, Yang Q, Huang H, Chen Z, Xiao Z, He Q
Clinical & experimental metastasis 2020 Aug;37(4):477-487
Clinical & experimental metastasis 2020 Aug;37(4):477-487
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544
Oncology letters 2020 Aug;20(2):1535-1544
Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease.
Mi Z, Song Y, Cao X, Lu Y, Liu Z, Zhu X, Geng M, Sun Y, Lan B, He C, Xiong H, Zhang L, Chen Y
Nature metabolism 2020 Aug;2(8):717-731
Nature metabolism 2020 Aug;2(8):717-731
Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.
Kalpage HA, Wan J, Morse PT, Lee I, Hüttemann M
Cells 2020 Aug 6;9(8)
Cells 2020 Aug 6;9(8)
Mechanical Ring Interfaces between Adherens Junction and Contractile Actomyosin to Coordinate Entotic Cell-in-Cell Formation.
Wang M, Niu Z, Qin H, Ruan B, Zheng Y, Ning X, Gu S, Gao L, Chen Z, Wang X, Huang H, Ma L, Sun Q
Cell reports 2020 Aug 25;32(8):108071
Cell reports 2020 Aug 25;32(8):108071
Regulation of Female Folliculogenesis by Tsp1a in Nile Tilapia (Oreochromis niloticus).
Jie M, Ma H, Zhou L, Wu J, Li M, Liu X, Wang D
International journal of molecular sciences 2020 Aug 16;21(16)
International journal of molecular sciences 2020 Aug 16;21(16)
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Fang Y, Li F, Qi C, Mao X, Xu Y, Zhao Z, Wu H, Zhang Z
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Cao Y, Liu C, Wang Q, Wang W, Tao E, Wan L
Experimental cell research 2020 Aug 1;393(1):112058
Experimental cell research 2020 Aug 1;393(1):112058
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
Huang J, Diao G, Zhang Q, Chen Y, Han J, Guo J
International journal of oncology 2020 Apr;56(4):921-931
International journal of oncology 2020 Apr;56(4):921-931
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
Wu Z, Zhang Y, Zhang Y, Zhao P
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down-regulating CCNE2 in pancreatic ductal adenocarcinoma.
Yang J, Dong Z, Ren A, Fu G, Zhang K, Li C, Wang X, Cui H
Journal of cellular and molecular medicine 2020 Apr;24(7):4245-4260
Journal of cellular and molecular medicine 2020 Apr;24(7):4245-4260
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Wang M, Wang H, Tao Z, Xia Q, Hao Z, Prehn JHM, Zhen X, Wang G, Ying Z
Aging cell 2020 Apr;19(4):e13126
Aging cell 2020 Apr;19(4):e13126
Alternatively Polarized Macrophages Regulate the Growth and Differentiation of Ependymal Stem Cells through the SIRT2 Pathway.
Ma Y, Deng M, Zhao XQ, Liu M
Experimental neurobiology 2020 Apr 30;29(2):150-163
Experimental neurobiology 2020 Apr 30;29(2):150-163
SIRT6-PARP1 is involved in HMGB1 polyADP-ribosylation and acetylation and promotes chemotherapy-induced autophagy in leukemia.
Kong Q, Li Y, Liang Q, Xie J, Li X, Fang J
Cancer biology & therapy 2020 Apr 2;21(4):320-331
Cancer biology & therapy 2020 Apr 2;21(4):320-331
Hepatic CD147 knockout modulates liver steatosis and up-regulates autophagy in high-fat-diet-induced NAFLD mice.
Lou J, Li C, Li ZS, Zhang T, Chen ZN, Bian H
Biochemical and biophysical research communications 2020 Apr 16;524(4):1010-1017
Biochemical and biophysical research communications 2020 Apr 16;524(4):1010-1017
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Zhang Y, Zhang X, Liang Z, Dai K, Zhu M, Zhang M, Pan J, Xue R, Cao G, Tang J, Song X, Hu X, Gong C
Aquaculture (Amsterdam, Netherlands) 2020 Apr 15;520:734969
Aquaculture (Amsterdam, Netherlands) 2020 Apr 15;520:734969
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma.
Lo WL, Hsu TI, Yang WB, Kao TJ, Wu MH, Huang YN, Yeh SH, Chuang JY
Cancers 2020 Apr 15;12(4)
Cancers 2020 Apr 15;12(4)
Ovarian cancer cell-secreted exosomal miR-205 promotes metastasis by inducing angiogenesis.
He L, Zhu W, Chen Q, Yuan Y, Wang Y, Wang J, Wu X
Theranostics 2019;9(26):8206-8220
Theranostics 2019;9(26):8206-8220
Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma.
Gao Y, Liu B, Feng L, Sun B, He S, Yang Y, Wu G, E G, Liu C, Gao Y, Zhang E, Zhu B
Frontiers in oncology 2019;9:33
Frontiers in oncology 2019;9:33
Identification of Aloperine as an anti-apoptotic Bcl2 protein inhibitor in glioma cells.
Xu Z, Wang X, Chen X, Zeng S, Qian L, Wei J, Gong Z, Yan Y
PeerJ 2019;7:e7652
PeerJ 2019;7:e7652
Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction.
Li L, Zhang J, Zhang Q, Huang Y, Hu J
Burns & trauma 2019;7:8
Burns & trauma 2019;7:8
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Li Y, Li X, Cao M, Jiang Y, Yan J, Liu Z, Yang R, Chen X, Sun P, Xiang R, Wang L, Shi Y
Signal transduction and targeted therapy 2019;4:50
Signal transduction and targeted therapy 2019;4:50
Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury.
Li L, Zhang X, Zhang Q, Jia J, Zhang J, Zhang D, Song H, Chen B, Hu J, Huang Y
Oxidative medicine and cellular longevity 2019;2019:6428924
Oxidative medicine and cellular longevity 2019;2019:6428924
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells.
Zeng Y, Pan Q, Wang X, Li D, Lin Y, Man F, Xiao F, Guo L
Oxidative medicine and cellular longevity 2019;2019:4508762
Oxidative medicine and cellular longevity 2019;2019:4508762
Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis.
Ye N, Zhang N, Zhang Y, Qian H, Wu B, Sun Y
Oxidative medicine and cellular longevity 2019;2019:4273261
Oxidative medicine and cellular longevity 2019;2019:4273261
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Xu X, Zong Y, Gao Y, Sun X, Zhao H, Luo W, Jia S
BioMed research international 2019;2019:3909102
BioMed research international 2019;2019:3909102
Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.
Zhu HF, Zhang XH, Gu CS, Zhong Y, Long T, Ma YD, Hu ZY, Li ZG, Wang XY
Cancer biology & therapy 2019;20(7):967-978
Cancer biology & therapy 2019;20(7):967-978
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Yang Z, Yu W, Huang R, Ye M, Min Z
Cancer cell international 2019;19:17
Cancer cell international 2019;19:17
Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation.
Zhang J, Li L, Zhang Q, Wang W, Zhang D, Jia J, Lv Y, Yuan H, Song H, Xiang F, Hu J, Huang Y
International journal of biological sciences 2019;15(9):1962-1976
International journal of biological sciences 2019;15(9):1962-1976
Histone Demethylase UTX is an Essential Factor for Zygotic Genome Activation and Regulates Zscan4 Expression in Mouse Embryos.
Bai L, Yang L, Zhao C, Song L, Liu X, Bai C, Su G, Wei Z, Li G
International journal of biological sciences 2019;15(11):2363-2372
International journal of biological sciences 2019;15(11):2363-2372
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Chen KY, Chen CC, Chang YC, Chang MC
PloS one 2019;14(7):e0219317
PloS one 2019;14(7):e0219317
Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells.
Chadchankar J, Korboukh V, Conway LC, Wobst HJ, Walker CA, Doig P, Jacobsen SJ, Brandon NJ, Moss SJ, Wang Q
PloS one 2019;14(11):e0225145
PloS one 2019;14(11):e0225145
Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway.
Tang S, Xin Y, Yang M, Zhang D, Xu C
International journal of clinical and experimental pathology 2019;12(6):2324-2338
International journal of clinical and experimental pathology 2019;12(6):2324-2338
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
Han N, Yuan F, Xian P, Liu N, Liu J, Zhang H, Zhang H, Yao K, Yuan G
OncoTargets and therapy 2019;12:7591-7599
OncoTargets and therapy 2019;12:7591-7599
Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway.
Xu T, Zhang R, Dong M, Zhang Z, Li H, Zhan C, Li X
OncoTargets and therapy 2019;12:10639-10650
OncoTargets and therapy 2019;12:10639-10650
Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction.
Li M, Chen C, Zhang W, Gao R, Wang Q, Chen H, Zhang S, Mao X, Leblanc M, Behensky A, Zhang Z, Gan L, Yu H, Zhu T, Liu J
Frontiers in aging neuroscience 2019;11:181
Frontiers in aging neuroscience 2019;11:181
Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway.
Liang Y, Zhu D, Zhu L, Hou Y, Hou L, Huang X, Li L, Wang Y, Li L, Zou H, Wu T, Yao M, Wang J, Meng X
Journal of Cancer 2019;10(24):6037-6047
Journal of Cancer 2019;10(24):6037-6047
Qingpeng Ointment Ameliorates Inflammatory Responses and Dysregulation of Itch-Related Molecules for Its Antipruritic Effects in Experimental Allergic Contact Dermatitis.
Gong X, Xiong H, Liu S, Liu Y, Yin L, Tu C, Wang H, Zhao Z, Chen W, Mei Z
Frontiers in pharmacology 2019;10:354
Frontiers in pharmacology 2019;10:354
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Ruan J, Cao Y, Ling T, Li P, Wu S, Peng D, Wang Y, Jia X, Chen S, Xu A, Yuan S
Frontiers in immunology 2019;10:2202
Frontiers in immunology 2019;10:2202
Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.
Chen DQ, Cao G, Zhao H, Chen L, Yang T, Wang M, Vaziri ND, Guo Y, Zhao YY
Therapeutic advances in chronic disease 2019;10:2040622319869116
Therapeutic advances in chronic disease 2019;10:2040622319869116
Functional role of GKAP1 in the regulation of male germ cell spontaneous apoptosis and sperm number.
Wang H, Wang G, Dai Y, Li Z, Zhu Y, Sun F
Molecular reproduction and development 2019 Sep;86(9):1199-1209
Molecular reproduction and development 2019 Sep;86(9):1199-1209
miR-125b-5p targeting TRAF6 relieves skeletal muscle atrophy induced by fasting or denervation.
Qiu J, Zhu J, Zhang R, Liang W, Ma W, Zhang Q, Huang Z, Ding F, Sun H
Annals of translational medicine 2019 Sep;7(18):456
Annals of translational medicine 2019 Sep;7(18):456
Calcium channel blockers reduce severe fever with thrombocytopenia syndrome virus (SFTSV) related fatality.
Li H, Zhang LK, Li SF, Zhang SF, Wan WW, Zhang YL, Xin QL, Dai K, Hu YY, Wang ZB, Zhu XT, Fang YJ, Cui N, Zhang PH, Yuan C, Lu QB, Bai JY, Deng F, Xiao GF, Liu W, Peng K
Cell research 2019 Sep;29(9):739-753
Cell research 2019 Sep;29(9):739-753
Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells.
Li L, Yan S, Zhang H, Zhang M, Huang G, Chen M
BMC cancer 2019 Sep 6;19(1):894
BMC cancer 2019 Sep 6;19(1):894
Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin.
Gao F, Liang Y, Zhou P, Cheng J, Ding K, Wang Y
European journal of medicinal chemistry 2019 Sep 15;178:177-194
European journal of medicinal chemistry 2019 Sep 15;178:177-194
Proteomics Profiling of Host Cell Response via Protein Expression and Phosphorylation upon Dengue Virus Infection.
Miao M, Yu F, Wang D, Tong Y, Yang L, Xu J, Qiu Y, Zhou X, Zhao X
Virologica Sinica 2019 Oct;34(5):549-562
Virologica Sinica 2019 Oct;34(5):549-562
In situ repurposing of dendritic cells with CRISPR/Cas9-based nanomedicine to induce transplant tolerance.
Zhang Y, Shen S, Zhao G, Xu CF, Zhang HB, Luo YL, Cao ZT, Shi J, Zhao ZB, Lian ZX, Wang J
Biomaterials 2019 Oct;217:119302
Biomaterials 2019 Oct;217:119302
TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production.
Fan C, Ji Q, Zhang C, Xu S, Sun H, Li Z
Molecular medicine reports 2019 Oct;20(4):3123-3130
Molecular medicine reports 2019 Oct;20(4):3123-3130
CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells.
Xu T, Yu X, Deng J, Ou S, Liu X, Wang T, Liu Y, Yang J, Tan C, Yuan J, Chen Y
Cell death & disease 2019 Oct 31;10(11):825
Cell death & disease 2019 Oct 31;10(11):825
NEDD4 protects vascular endothelial cells against Angiotensin II-induced cell death via enhancement of XPO1-mediated nuclear export.
Xu J, Sheng Z, Li F, Wang S, Yuan Y, Wang M, Yu Z
Experimental cell research 2019 Oct 1;383(1):111505
Experimental cell research 2019 Oct 1;383(1):111505
The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosis.
Chen P, Wang B, Mo Q, Wu P, Fang Y, Tian Y, Jin X, Gao Y, Wu Y, Cao Y, Zhang Y, Xi L, Wang S, Hu J, Ma D, Zhou J, Gao Q, Chen G
EBioMedicine 2019 Nov;49:26-39
EBioMedicine 2019 Nov;49:26-39
Endoplasmic reticulum stress, a novel significant mechanism responsible for DEHP-induced increased distance between seminiferous tubule of mouse testis.
Pan J, Yao Y, Guo X, Kong F, Zhou J, Meng X
Journal of cellular physiology 2019 Nov;234(11):19807-19823
Journal of cellular physiology 2019 Nov;234(11):19807-19823
Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2.
Sun Z, Lu J, Wu M, Li M, Bai L, Shi Z, Hao L, Wu Y
Molecular medicine reports 2019 Nov;20(5):4235-4243
Molecular medicine reports 2019 Nov;20(5):4235-4243
MicroRNA-125a-3p affects smooth muscle cell function in vascular stenosis.
Hu W, Chang G, Zhang M, Li Y, Yin L, Huang Y, Feng C, Gu Y, Wen D, Wang S
Journal of molecular and cellular cardiology 2019 Nov;136:85-94
Journal of molecular and cellular cardiology 2019 Nov;136:85-94
ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma.
Liang B, Chen R, Song S, Wang H, Sun G, Yang H, Jing W, Zhou X, Fu Z, Huang G, Zhao J
Cell death & disease 2019 Nov 4;10(11):830
Cell death & disease 2019 Nov 4;10(11):830
Bioinformatics Analysis Identifies Protein Tyrosine Kinase 7 (PTK7) as a Potential Prognostic and Therapeutic Biomarker in Stages I to IV Hepatocellular Carcinoma.
Zou RC, Liang Y, Li LL, Tang JZ, Yang YP, Geng YC, He J, Luo LY, Li WX, Sun ZW, Yuan HL
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 15;25:8618-8627
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 15;25:8618-8627
Mitochondrial pyruvate carrier 2 mediates mitochondrial dysfunction and apoptosis in high glucose-treated podocytes.
Feng J, Ma Y, Chen Z, Hu J, Yang Q, Ding G
Life sciences 2019 Nov 15;237:116941
Life sciences 2019 Nov 15;237:116941
Enhancement of cortisol-induced SAA1 transcription by SAA1 in the human amnion.
Lu Y, Wang WS, Lin YK, Lu JW, Li WJ, Zhang CY, Sun K
Journal of molecular endocrinology 2019 May;62(4):149-158
Journal of molecular endocrinology 2019 May;62(4):149-158
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Sheng J, Shen L, Sun L, Zhang X, Cui R, Wang L
Cell proliferation 2019 May;52(3):e12609
Cell proliferation 2019 May;52(3):e12609
Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation.
Shan A, Lu J, Xu Z, Li X, Xu Y, Li W, Liu F, Yang F, Sato T, Narimatsu H, Zhang Y
Biochimica et biophysica acta. General subjects 2019 May;1863(5):870-882
Biochimica et biophysica acta. General subjects 2019 May;1863(5):870-882
Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels.
Li N, Wang T, Li Z, Ye X, Deng B, Zhuo S, Yao P, Yang M, Mei H, Chen X, Zhu T, Chen S, Wang H, Wang J, Le Y
Cancer biology & medicine 2019 May;16(2):220-233
Cancer biology & medicine 2019 May;16(2):220-233
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X
Cells 2019 May 5;8(5)
Cells 2019 May 5;8(5)
PTK2 promotes cancer stem cell traits in hepatocellular carcinoma by activating Wnt/β-catenin signaling.
Fan Z, Duan J, Wang L, Xiao S, Li L, Yan X, Yao W, Wu L, Zhang S, Zhang Y, Li Y, Zhu X, Hu Y, Zhang D, Jiao S, Xu X
Cancer letters 2019 May 28;450:132-143
Cancer letters 2019 May 28;450:132-143
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Zhang X, Ge Y, Bukhari AA, Zhu Q, Shen Y, Li M, Sun H, Su D, Liang X
Experimental & molecular medicine 2019 May 21;51(5):1-12
Experimental & molecular medicine 2019 May 21;51(5):1-12
Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.
Han M, Zhao M, Cheng C, Huang Y, Han S, Li W, Tu X, Luo X, Yu X, Liu Y, Chen Q, Ren X, Wang QK, Ke T
Human mutation 2019 Mar;40(3):310-325
Human mutation 2019 Mar;40(3):310-325
NFAT1 Hypermethylation Promotes Epithelial-Mesenchymal Transition and Metastasis in Nasopharyngeal Carcinoma by Activating ITGA6 Transcription.
Zhang J, Zheng ZQ, Yuan YW, Zhang PP, Li YQ, Wang YQ, Tang XR, Wen X, Hong XH, Lei Y, He QM, Yang XJ, Sun Y, Ma J, Liu N
Neoplasia (New York, N.Y.) 2019 Mar;21(3):311-321
Neoplasia (New York, N.Y.) 2019 Mar;21(3):311-321
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
Wang Q, Shi W
Oncology letters 2019 Mar;17(3):2976-2982
Oncology letters 2019 Mar;17(3):2976-2982
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
Hu X, Lu Z, Yu S, Reilly J, Liu F, Jia D, Qin Y, Han S, Liu X, Qu Z, Lv Y, Li J, Huang Y, Jiang T, Jia H, Wang Q, Liu J, Shu X, Tang Z, Liu M
Autophagy 2019 Mar;15(3):453-465
Autophagy 2019 Mar;15(3):453-465
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
Sun X, Xie Y, Sun X, Yao Y, Li H, Li Z, Yao R, Xu K
Bioscience reports 2019 Mar 29;39(3)
Bioscience reports 2019 Mar 29;39(3)
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
Pettee KM, Becker KN, Alberts AS, Reinard KA, Schroeder JL, Eisenmann KM
Cancers 2019 Mar 20;11(3)
Cancers 2019 Mar 20;11(3)
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress.
Wang J, Wu Q, Qiu J
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):898-908
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):898-908
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Mao Z, Lin H, Su W, Li J, Zhou M, Li Z, Zhou B, Yang Q, Zhou M, Pan K, He J, Zhang W
Diabetes 2019 Jun;68(6):1197-1209
Diabetes 2019 Jun;68(6):1197-1209
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, Liu Z, Yao Z, Wu Q, Liao W, Zhang S, Liu Y, Xiang Y, Liu J, Shi M
Oncogene 2019 Jun;38(23):4637-4654
Oncogene 2019 Jun;38(23):4637-4654
MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte.
Wan GX, Cheng L, Qin HL, Zhang YZ, Wang LY, Zhang YG
Cardiovascular toxicology 2019 Jun;19(3):264-275
Cardiovascular toxicology 2019 Jun;19(3):264-275
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.
Aghajan M, Booten SL, Althage M, Hart CE, Ericsson A, Maxvall I, Ochaba J, Menschik-Lundin A, Hartleib J, Kuntz S, Gattis D, Ahlström C, Watt AT, Engelhardt JA, Monia BP, Magnone MC, Guo S
JCI insight 2019 Jun 20;4(12)
JCI insight 2019 Jun 20;4(12)
The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.
Kong M, Wu J, Fan Z, Chen B, Wu T, Xu Y
Biochemical and biophysical research communications 2019 Jun 18;514(1):16-23
Biochemical and biophysical research communications 2019 Jun 18;514(1):16-23
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Wang R, Li D, Ouyang J, Tian X, Zhao Y, Peng X, Li S, Yu G, Yang J
Toxicology 2019 Jun 15;422:1-13
Toxicology 2019 Jun 15;422:1-13
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs.
Gao H, Gao R, Zhang L, Xiu W, Zang R, Wang H, Zhang Y, Chen J, Gao Y, Gao S
Journal of molecular cell biology 2019 Jun 1;11(6):463-473
Journal of molecular cell biology 2019 Jun 1;11(6):463-473
Dendrobium officinale polysaccharides regulate age-related lineage commitment between osteogenic and adipogenic differentiation.
Peng H, Yang M, Guo Q, Su T, Xiao Y, Xia ZY
Cell proliferation 2019 Jul;52(4):e12624
Cell proliferation 2019 Jul;52(4):e12624
Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning.
Ma P, Song NN, Li Y, Zhang Q, Zhang L, Zhang L, Kong Q, Ma L, Yang X, Ren B, Li C, Zhao X, Li Y, Xu Y, Gao X, Ding YQ, Mao B
Cell reports 2019 Jul 9;28(2):541-553.e4
Cell reports 2019 Jul 9;28(2):541-553.e4
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
Sun S, Cai B, Li Y, Su W, Zhao X, Gong B, Li Z, Zhang X, Wu Y, Chen C, Tsang SH, Yang J, Li X
Aging 2019 Jul 7;11(13):4323-4337
Aging 2019 Jul 7;11(13):4323-4337
NPRL2 enhances autophagy and the resistance to Everolimus in castration-resistant prostate cancer.
Chen Z, Jiang Q, Zhu P, Chen Y, Xie X, Du Z, Jiang L, Tang W
The Prostate 2019 Jan;79(1):44-53
The Prostate 2019 Jan;79(1):44-53
FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma.
Chen C, Han G, Li Y, Yue Z, Wang L, Liu J
Journal of cellular biochemistry 2019 Jan;120(1):882-893
Journal of cellular biochemistry 2019 Jan;120(1):882-893
The pivotal role of protein acetylation in linking glucose and fatty acid metabolism to β-cell function.
Zhang Y, Zhou F, Bai M, Liu Y, Zhang L, Zhu Q, Bi Y, Ning G, Zhou L, Wang X
Cell death & disease 2019 Jan 25;10(2):66
Cell death & disease 2019 Jan 25;10(2):66
HOXA9 is a novel myopia risk gene.
Liang CL, Hsu PY, Ngo CS, Seow WJ, Karnani N, Pan H, Saw SM, Juo SH
BMC ophthalmology 2019 Jan 23;19(1):28
BMC ophthalmology 2019 Jan 23;19(1):28
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Shi H, Wang XL, Quan HF, Yan L, Pei XY, Wang R, Peng XD
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.
Blenski M, Kehlenbach RH
International journal of molecular sciences 2019 Jan 15;20(2)
International journal of molecular sciences 2019 Jan 15;20(2)
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Han Y, Wu P, Wang Z, Zhang Z, Sun S, Liu J, Gong S, Gao P, Iwakuma T, Molina-Vila MA, Chen BP, Zhang Y, Ji T, Mo Q, Chen P, Hu J, Wang S, Zhou J, Lu H, Gao Q
EBioMedicine 2019 Feb;40:92-105
EBioMedicine 2019 Feb;40:92-105
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
Zhai J, Geng X, Ding T, Li J, Tang J, Chen D, Cui L, Wang Q
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
CD147 promotes progression of head and neck squamous cell carcinoma via NF-kappa B signaling.
Yu B, Zhang Y, Wu K, Wang L, Jiang Y, Chen W, Yan M
Journal of cellular and molecular medicine 2019 Feb;23(2):954-966
Journal of cellular and molecular medicine 2019 Feb;23(2):954-966
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
Ma H, Yang W, Zhang L, Liu S, Zhao M, Zhou G, Wang L, Jin S, Zhang Z, Hu J
British journal of cancer 2019 Feb;120(3):317-330
British journal of cancer 2019 Feb;120(3):317-330
AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness.
Wang X, Jin J, Wan F, Zhao L, Chu H, Chen C, Liao G, Liu J, Yu Y, Teng H, Fang L, Jiang C, Pan W, Xie X, Li J, Lu X, Jiang X, Ge X, Ye D, Wang P
Developmental cell 2019 Feb 11;48(3):345-360.e7
Developmental cell 2019 Feb 11;48(3):345-360.e7
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Li W, Zhang J, Zou L, Cui J, Su F, Jin J, Xiao F, Liu M, Zhao G
Oncology reports 2019 Dec;42(6):2788-2796
Oncology reports 2019 Dec;42(6):2788-2796
Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer.
Cai Z, Liang Y, Xing C, Wang H, Hu P, Li J, Huang H, Wang W, Jiang C
Oncology reports 2019 Dec;42(6):2537-2549
Oncology reports 2019 Dec;42(6):2537-2549
Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A3 Adenosine Receptor.
Fujimoto K, Shioi A, Miki Y, Kakutani Y, Morioka T, Shoji T, Emoto M, Inaba M
The Tohoku journal of experimental medicine 2019 Dec;249(4):275-283
The Tohoku journal of experimental medicine 2019 Dec;249(4):275-283
Small GTPase Arf6 regulates diabetes-induced cholesterol accumulation in podocytes.
Hu J, Yang Q, Chen Z, Liang W, Feng J, Ding G
Journal of cellular physiology 2019 Dec;234(12):23559-23570
Journal of cellular physiology 2019 Dec;234(12):23559-23570
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
Dai L, Zhou J, Li T, Qian Y, Jin L, Zhu C, Li S
Journal of cellular physiology 2019 Dec;234(12):22463-22476
Journal of cellular physiology 2019 Dec;234(12):22463-22476
Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line.
Han J, Tang Y, Zhong M, Wu W
Molecular medicine reports 2019 Dec;20(6):5064-5074
Molecular medicine reports 2019 Dec;20(6):5064-5074
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Shi J, Hu X, Guo Y, Wang L, Ji J, Li J, Zhang ZR
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases.
Gomez RC, Wawro P, Lis P, Alessi DR, Pfeffer SR
The Journal of cell biology 2019 Dec 2;218(12):4157-4170
The Journal of cell biology 2019 Dec 2;218(12):4157-4170
Targeting CDK12-mediated transcription regulation in anaplastic thyroid carcinoma.
Geng M, Yang Y, Cao X, Dang L, Zhang T, Zhang L
Biochemical and biophysical research communications 2019 Dec 10;520(3):544-550
Biochemical and biophysical research communications 2019 Dec 10;520(3):544-550
Involvement of STAT3 in the synergistic induction of 11β-HSD1 by SAA1 and cortisol in human amnion fibroblasts.
Lu Y, Zhou Q, Lu JW, Wang WS, Sun K
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Aug;82(2):e13150
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Aug;82(2):e13150
Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction.
Chen C, Gao R, Li M, Wang Q, Chen H, Zhang S, Mao X, Behensky A, Zhang Z, Gan L, Li T, Liao R, Li Q, Yu H, Yang J, Zhu T, Liu J
Brain, behavior, and immunity 2019 Aug;80:439-451
Brain, behavior, and immunity 2019 Aug;80:439-451
The Mechanism of Rap1 Regulates N-cadherin to Control Neuronal Migration.
Yang C, Li X, Zhang B, Fu S, Li S, Shen J, Guan L, Qiao L, Lin J
Journal of molecular neuroscience : MN 2019 Aug;68(4):539-548
Journal of molecular neuroscience : MN 2019 Aug;68(4):539-548
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation.
Ren QC, Li XH, Li QY, Yang HL, Wang HL, Zhang H, Zhao L, Jiang-Yong SL, Meng XL, Zhang Y, Shen XF
Phytotherapy research : PTR 2019 Aug;33(8):2102-2117
Phytotherapy research : PTR 2019 Aug;33(8):2102-2117
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
Nakamura H, Shimizu T, Takatani A, Suematsu T, Nakamura T, Kawakami A
Virus research 2019 Aug;269:197643
Virus research 2019 Aug;269:197643
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Li X, Zhang N, Zhang Y, Jia P, Guo Y, Tian Y, You S, Wu S, Sun Y
Molecular medicine reports 2019 Aug;20(2):1561-1568
Molecular medicine reports 2019 Aug;20(2):1561-1568
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Uemura T, Suzuki T, Ko K, Watanabe K, Dohmae N, Sakamoto A, Terui Y, Toida T, Kashiwagi K, Igarashi K
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
Wang Q, Ye S, Chen X, Xu P, Li K, Zeng S, Huang M, Gao W, Chen J, Zhang Q, Zhong Z, Liu Q
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
Krüppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome.
Yang M, Guo Q, Peng H, Xiao YZ, Xiao Y, Huang Y, Li CJ, Su T, Zhang YL, Lei MX, Chen HL, Jiang TJ, Luo XH
The Journal of experimental medicine 2019 Aug 5;216(8):1944-1964
The Journal of experimental medicine 2019 Aug 5;216(8):1944-1964
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
Yang X, Wang G, Cao T, Zhang L, Ma Y, Jiang S, Teng X, Sun X
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932
PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-κB signaling pathway.
Chen L, Sun X, Xiao H, Xu F, Yang Y, Lin Z, Chen Z, Quan S, Huang H
Experimental cell research 2019 Aug 15;381(2):301-310
Experimental cell research 2019 Aug 15;381(2):301-310
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells.
Barot S, Abo-Ali EM, Zhou DL, Palaguachi C, Dukhande VV
Experimental cell research 2019 Aug 15;381(2):288-300
Experimental cell research 2019 Aug 15;381(2):288-300
The Novel Nature Microtubule Inhibitor Ivalin Induces G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells In Vitro.
Liu F, Lin S, Zhang C, Ma J, Han Z, Jia F, Xie W, Li X
Medicina (Kaunas, Lithuania) 2019 Aug 12;55(8)
Medicina (Kaunas, Lithuania) 2019 Aug 12;55(8)
Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation.
Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, Tong X, Chen L, Liu X, Zhang Y, Zhu X, Li X, Zhang H, Bai H, Yang Q, Ma J, Wiemer EAC, Xu Y, Chen Q
Nature communications 2019 Apr 17;10(1):1801
Nature communications 2019 Apr 17;10(1):1801
Altered expression of p63 isoforms and expansion of p63- and club cell secretory protein-positive epithelial cells in the lung as novel features of aging.
Fukumoto J, Sidramagowda Patil S, Krishnamurthy S, Saji S, John I, Narala VR, Hernández-Cuervo H, Alleyn M, Breitzig MT, Galam L, Soundararajan R, Chaudhari UK, Hansen BC, Lockey RF, Kolliputi N
American journal of physiology. Cell physiology 2019 Apr 1;316(4):C492-C508
American journal of physiology. Cell physiology 2019 Apr 1;316(4):C492-C508
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Chen DQ, Cao G, Chen H, Argyopoulos CP, Yu H, Su W, Chen L, Samuels DC, Zhuang S, Bayliss GP, Zhao S, Yu XY, Vaziri ND, Wang M, Liu D, Mao JR, Ma SX, Zhao J, Zhang Y, Shang YQ, Kang H, Ye F, Cheng XH, Li XR, Zhang L, Meng MX, Guo Y, Zhao YY
Nature communications 2019 Apr 1;10(1):1476
Nature communications 2019 Apr 1;10(1):1476
Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection.
Song F, Yu X, Zhong T, Wang Z, Meng X, Li Z, Zhang S, Huo W, Liu X, Zhang Y, Zhang W, Yu J
Frontiers in microbiology 2018;9:817
Frontiers in microbiology 2018;9:817
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Feng Y, Chu A, Luo Q, Wu M, Shi X, Chen Y
Frontiers in pharmacology 2018;9:748
Frontiers in pharmacology 2018;9:748
Fas Signaling in Dendritic Cells Mediates Th2 Polarization in HDM-Induced Allergic Pulmonary Inflammation.
Han M, Hu R, Ma J, Zhang B, Chen C, Li H, Yang J, Huang G
Frontiers in immunology 2018;9:3045
Frontiers in immunology 2018;9:3045
TRIM31 Deficiency Is Associated with Impaired Glucose Metabolism and Disrupted Gut Microbiota in Mice.
Cheng J, Xue F, Zhang M, Cheng C, Qiao L, Ma J, Sui W, Xu X, Gao C, Hao P, Zhang M, Zhang Y
Frontiers in physiology 2018;9:24
Frontiers in physiology 2018;9:24
Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6.
Li Z, Jia Y, Han S, Wang X, Han F, Zhang J, Zhang W, Guan H, Hu D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2278-2290
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2278-2290
Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway.
Chen Y, Chang Y, Zhang N, Guo X, Sun G, Sun Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1009-1018
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1009-1018
Resveratrol-Induced Downregulation of NAF-1 Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine via the ROS/Nrf2 Signaling Pathways.
Cheng L, Yan B, Chen K, Jiang Z, Zhou C, Cao J, Qian W, Li J, Sun L, Ma J, Ma Q, Sha H
Oxidative medicine and cellular longevity 2018;2018:9482018
Oxidative medicine and cellular longevity 2018;2018:9482018
MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3.
Wang YX, Zhu HF, Zhang ZY, Ren F, Hu YH
Cancer cell international 2018;18:124
Cancer cell international 2018;18:124
XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer.
Li Q, Ma R, Zhang M
OncoTargets and therapy 2018;11:8435-8444
OncoTargets and therapy 2018;11:8435-8444
Liver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma.
Yang LH, Wang Y, Qiao S, Wang MJ, Chen F, Zi XY, Li JX, Zhang HB, Yu B, Hu YP
Cancer management and research 2018;10:873-885
Cancer management and research 2018;10:873-885
The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation.
Zhou X, Yong L, Huang Y, Zhu S, Song X, Li B, Zhu J, Wang H
Journal of cellular physiology 2018 Sep;233(9):6902-6910
Journal of cellular physiology 2018 Sep;233(9):6902-6910
The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Li J, Peng W, Du L, Yang Q, Wang C, Mo YY
Journal of cellular and molecular medicine 2018 Sep;22(9):4486-4495
Journal of cellular and molecular medicine 2018 Sep;22(9):4486-4495
Oocyte-specific deletion of Gsα induces oxidative stress and deteriorates oocyte quality in mice.
Xie Y, Wu B, Jin Y, Zhang A, Sun X, Zhang X, Gao X, Dong R, Li H, Gao J
Experimental cell research 2018 Sep 15;370(2):579-590
Experimental cell research 2018 Sep 15;370(2):579-590
XPO1-mediated nuclear export of RNF146 protects from angiotensin II-induced endothelial cellular injury.
Sheng Z, Xu Y, Wang S, Yuan Y, Huang T, Lu P
Biochemical and biophysical research communications 2018 Sep 10;503(3):1544-1549
Biochemical and biophysical research communications 2018 Sep 10;503(3):1544-1549
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Ren Y, Chen J, Wu X, Gui C, Mao K, Zou F, Li W
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
β-catenin regulates IRF3-mediated innate immune signalling in colorectal cancer.
Ding C, He J, Zhao J, Li J, Chen J, Liao W, Zeng Y, Zhong J, Wei C, Zhang L, Zhou M, Jia Z, Zhang Y, Li H, Zhou Y, Xiao X, Han D, Li C, Zhu Z, Xia Z, Peng J
Cell proliferation 2018 Oct;51(5):e12464
Cell proliferation 2018 Oct;51(5):e12464
Inhibitor of apoptosis protein‑like protein‑2: A novel growth accelerator for breast cancer cells.
Zhu L, Zhou W, Zhu X, Xiang S, Wang S, Peng Y, Lu B, Tang P, Chen Q, Wu M, Peng X, Chen Z, Sun Z, Yang K, Xiang M, Yu D
Oncology reports 2018 Oct;40(4):2047-2055
Oncology reports 2018 Oct;40(4):2047-2055
Low-density lipoprotein receptor-related protein 6 regulates alternative pre-mRNA splicing.
Yuan T, Wang S, Hu C, Wu Y, Liang D, Li L, Liu Y, Li J, Chen YH
Journal of cellular and molecular medicine 2018 Oct;22(10):4653-4663
Journal of cellular and molecular medicine 2018 Oct;22(10):4653-4663
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Yu B, Wu K, Wang X, Zhang J, Wang L, Jiang Y, Zhu X, Chen W, Yan M
Cell death & disease 2018 Oct 22;9(11):1082
Cell death & disease 2018 Oct 22;9(11):1082
Administration of ubiquitin-activating enzyme UBA1 inhibitor PYR-41 attenuates angiotensin II-induced cardiac remodeling in mice.
Shu Q, Lai S, Wang XM, Zhang YL, Yang XL, Bi HL, Li HH
Biochemical and biophysical research communications 2018 Oct 20;505(1):317-324
Biochemical and biophysical research communications 2018 Oct 20;505(1):317-324
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Liu L, Shen Y, Zhu X, Lv R, Li S, Zhang Z, Shi YG, Tan L
Biochemical and biophysical research communications 2018 Oct 20;505(1):157-161
Biochemical and biophysical research communications 2018 Oct 20;505(1):157-161
Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.
Bi D, Yu B, Han Q, Lu J, White WL, Lai Q, Cai N, Luo W, Gu L, Li S, Xu H, Hu Z, Nie S, Xu X
Journal of agricultural and food chemistry 2018 Oct 17;66(41):10721-10728
Journal of agricultural and food chemistry 2018 Oct 17;66(41):10721-10728
Nucleoporin35 is a novel microtubule associated protein functioning in oocyte meiotic spindle architecture.
Chen F, Jiao XF, Zhang JY, Wu D, Ding ZM, Wang YS, Miao YL, Huo LJ
Experimental cell research 2018 Oct 15;371(2):435-443
Experimental cell research 2018 Oct 15;371(2):435-443
Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
Li L, Zhang Q, Zhang X, Zhang J, Wang X, Ren J, Jia J, Zhang D, Jiang X, Zhang J, Mei H, Chen B, Hu J, Huang Y
EBioMedicine 2018 Nov;37:221-235
EBioMedicine 2018 Nov;37:221-235
Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent.
Alsousi AA, Igwe OJ
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3847-3858
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3847-3858
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH
Neurochemistry international 2018 Nov;120:238-250
Neurochemistry international 2018 Nov;120:238-250
TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure.
Li Z, Liu T, Ma J, Guo Q, Ma L, Lv Q, Jiang Y, Wei C, Zhang J
Aging 2018 Nov 28;10(11):3474-3485
Aging 2018 Nov 28;10(11):3474-3485
Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways.
Sun X, Liu S, Wang J, Wei B, Guo C, Chen C, Sun MZ
Cell death & disease 2018 May 25;9(6):637
Cell death & disease 2018 May 25;9(6):637
HSF4 transcriptional regulates HMOX-1 expression in HLECs.
Liao S, Qu Z, Li L, Zhou B, Gao M, Huang M, Li D
Gene 2018 May 20;655:30-34
Gene 2018 May 20;655:30-34
Targeting LC3 and Beclin-1 autophagy genes suppresses proliferation, survival, migration and invasion by inhibition of Cyclin-D1 and uPAR/Integrin β1/ Src signaling in triple negative breast cancer cells.
Hamurcu Z, Delibaşı N, Geçene S, Şener EF, Dönmez-Altuntaş H, Özkul Y, Canatan H, Ozpolat B
Journal of cancer research and clinical oncology 2018 Mar;144(3):415-430
Journal of cancer research and clinical oncology 2018 Mar;144(3):415-430
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.
Tata PR, Chow RD, Saladi SV, Tata A, Konkimalla A, Bara A, Montoro D, Hariri LP, Shih AR, Mino-Kenudson M, Mou H, Kimura S, Ellisen LW, Rajagopal J
Developmental cell 2018 Mar 26;44(6):679-693.e5
Developmental cell 2018 Mar 26;44(6):679-693.e5
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, Li Y, You W, Dong Q, Hong T, Yan Z, Jin S, Wang T, Zhao W, Mai H, Huang J, Han X, Ji Q, Song Q, Yang C, Zhao S, Xu X, Ye Q
Cancer cell 2018 Mar 12;33(3):368-385.e7
Cancer cell 2018 Mar 12;33(3):368-385.e7
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Jin S, Ma H, Yang W, Ju H, Wang L, Zhang Z
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
High expression of NPRL2 is linked to poor prognosis in patients with prostate cancer.
Chen Z, Luo S, Chen Y, Xie X, Du Z, Jiang L
Human pathology 2018 Jun;76:141-148
Human pathology 2018 Jun;76:141-148
Sofosbuvir inhibits hepatitis A virus replication in vitro assessed by a cell-based fluorescent reporter system.
Jiang W, Muhammad F, Ma P, Liu X, Long G
Antiviral research 2018 Jun;154:51-57
Antiviral research 2018 Jun;154:51-57
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.
Sun X, Huang S, Wang X, Zhang X, Wang X
Oncotarget 2018 Jun 8;9(44):27574-27584
Oncotarget 2018 Jun 8;9(44):27574-27584
HuR regulates telomerase activity through TERC methylation.
Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z, Ma W, Zhao Y, Wang X, Ma J, Gorospe M, Ju Z, Wang W
Nature communications 2018 Jun 7;9(1):2213
Nature communications 2018 Jun 7;9(1):2213
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Zhang S, Xie C, Li H, Zhang K, Li J, Wang X, Yin Z
Laboratory investigation; a journal of technical methods and pathology 2018 Jul;98(7):883-894
Laboratory investigation; a journal of technical methods and pathology 2018 Jul;98(7):883-894
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
Lu M, Wu J, Hao ZW, Shang YK, Xu J, Nan G, Li X, Chen ZN, Bian H
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis.
Wang M, Chen DQ, Chen L, Cao G, Zhao H, Liu D, Vaziri ND, Guo Y, Zhao YY
British journal of pharmacology 2018 Jul;175(13):2689-2708
British journal of pharmacology 2018 Jul;175(13):2689-2708
Epigenetic activation of PERP transcription by MKL1 contributes to ROS-induced apoptosis in skeletal muscle cells.
Li Z, Chen B, Dong W, Xu W, Song M, Fang M, Guo J, Xu Y
Biochimica et biophysica acta. Gene regulatory mechanisms 2018 Jul 27;
Biochimica et biophysica acta. Gene regulatory mechanisms 2018 Jul 27;
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
Liu Z, Zhang Z, Huang M, Sun X, Liu B, Guo Q, Chang Q, Duan Z
BMC gastroenterology 2018 Jul 11;18(1):112
BMC gastroenterology 2018 Jul 11;18(1):112
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
Cheng Y, Zhao P, Wu S, Yang T, Chen Y, Zhang X, He C, Zheng C, Li K, Ma X, Xiang G
International journal of pharmaceutics 2018 Jul 10;545(1-2):261-273
International journal of pharmaceutics 2018 Jul 10;545(1-2):261-273
Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.
Sun Y, Bao Q, Xuan B, Xu W, Pan D, Li Q, Qian Z
Journal of virology 2018 Jul 1;92(13)
Journal of virology 2018 Jul 1;92(13)
Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation.
Cao YM, Gu J, Zhang YS, Wei WJ, Qu N, Wen D, Liao T, Shi RL, Zhang L, Ji QH, Wang Y, Sun GH, Zhao YX, Wang YJ, Yu J, Zhu YX
Oncology reports 2018 Jan;39(1):338-348
Oncology reports 2018 Jan;39(1):338-348
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage.
Zhang Y, Igwe OJ
Biochemical pharmacology 2018 Jan;147:104-118
Biochemical pharmacology 2018 Jan;147:104-118
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y
European journal of medicinal chemistry 2018 Jan 20;144:817-842
European journal of medicinal chemistry 2018 Jan 20;144:817-842
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Li L, Yang H, He Y, Li T, Feng J, Chen W, Ao L, Shi X, Lin Y, Liu H, Zheng E, Lin Q, Bu J, Zeng Y, Zheng M, Xu Y, Liao Z, Lin J, Lin D
Molecular and cellular biology 2018 Jan 15;38(2)
Molecular and cellular biology 2018 Jan 15;38(2)
Novel RAS Inhibitors Poricoic Acid ZG and Poricoic Acid ZH Attenuate Renal Fibrosis via a Wnt/β-Catenin Pathway and Targeted Phosphorylation of smad3 Signaling.
Wang M, Chen DQ, Chen L, Liu D, Zhao H, Zhang ZH, Vaziri ND, Guo Y, Zhao YY, Cao G
Journal of agricultural and food chemistry 2018 Feb 28;66(8):1828-1842
Journal of agricultural and food chemistry 2018 Feb 28;66(8):1828-1842
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Ma H, Jin S, Yang W, Zhou G, Zhao M, Fang S, Zhang Z, Hu J
British journal of cancer 2018 Feb 20;118(4):509-521
British journal of cancer 2018 Feb 20;118(4):509-521
Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells.
Meng D, Li Z, Wang G, Ling L, Wu Y, Zhang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1617-1627
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1617-1627
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
Wang T, Wang D, Zhang Y, Zhang J, Sun X, Wu Y, Wang S, Zhang Y, Xu L, Kong Q, Gao Y, Wu Y, Liu F, Liu S, Zhang Y, Lei T, Liu H
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
Hypothalamic DNA methylation in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture.
Cui P, Ma T, Tamadon A, Han S, Li B, Chen Z, An X, Shao LR, Wang Y, Feng Y
Experimental physiology 2018 Dec;103(12):1618-1632
Experimental physiology 2018 Dec;103(12):1618-1632
TUSC3 accelerates cancer growth and induces epithelial-mesenchymal transition by upregulating claudin-1 in non-small-cell lung cancer cells.
Feng S, Zhai J, Lu D, Lin J, Dong X, Liu X, Wu H, Roden AC, Brandi G, Tavolari S, Bille A, Cai K
Experimental cell research 2018 Dec 15;373(1-2):44-56
Experimental cell research 2018 Dec 15;373(1-2):44-56
Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation.
Wang YQ, Wei JG, Tu MJ, Gu JG, Zhang W
International journal of molecular sciences 2018 Dec 14;19(12)
International journal of molecular sciences 2018 Dec 14;19(12)
Aging-dependent decrease in the numbers of enteric neurons, interstitial cells of Cajal and expression of connexin43 in various regions of gastrointestinal tract.
Sun T, Li D, Hu S, Huang L, Sun H, Yang S, Wu B, Ji F, Zhou D
Aging 2018 Dec 11;10(12):3851-3865
Aging 2018 Dec 11;10(12):3851-3865
Expression profiling identified IL-8 as a regulator of homotypic cell-in-cell formation.
Ruan B, Wang C, Chen A, Liang J, Niu Z, Zheng Y, Fan J, Gao L, Huang H, Wang X, Sun Q
BMB reports 2018 Aug;51(8):412-417
BMB reports 2018 Aug;51(8):412-417
Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells.
Huang B, Lv DJ, Wang C, Shu FP, Gong ZC, Xie T, Yu YZ, Song XL, Xie JJ, Li S, Liu YM, Qi H, Zhao SC
Oncology letters 2018 Aug;16(2):2271-2278
Oncology letters 2018 Aug;16(2):2271-2278
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
Song GL, Chen C, Wu QY, Zhang ZH, Zheng R, Chen Y, Jia SZ, Ni JZ
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115
SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
Qin K, Zhang N, Zhang Z, Nipper M, Zhu Z, Leighton J, Xu K, Musi N, Wang P
Diabetologia 2018 Apr;61(4):906-918
Diabetologia 2018 Apr;61(4):906-918
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.
Pao KC, Wood NT, Knebel A, Rafie K, Stanley M, Mabbitt PD, Sundaramoorthy R, Hofmann K, van Aalten DMF, Virdee S
Nature 2018 Apr;556(7701):381-385
Nature 2018 Apr;556(7701):381-385
Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53.
Chen K, Zhang F, Ding J, Liang Y, Zhan Z, Zhan Y, Chen LH, Ding Y
Journal of Cancer 2017;8(16):3318-3330
Journal of Cancer 2017;8(16):3318-3330
Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6.
Zan J, Liu S, Sun DN, Mo KK, Yan Y, Liu J, Hu BL, Gu JY, Liao M, Zhou JY
Frontiers in cellular and infection microbiology 2017;7:146
Frontiers in cellular and infection microbiology 2017;7:146
Hydrogen sulfide generation from l-cysteine in the human glioblastoma-astrocytoma U-87 MG and neuroblastoma SHSY5Y cell lines.
Bronowicka-Adamska P, Bentke A, Wróbel M
Acta biochimica Polonica 2017;64(1):171-176
Acta biochimica Polonica 2017;64(1):171-176
HMGB1 binding heptamer peptide improves survival and ameliorates brain injury in rats after cardiac arrest and cardiopulmonary resuscitation.
Shi X, Li M, Huang K, Zhou S, Hu Y, Pan S, Gu Y
Neuroscience 2017 Sep 30;360:128-138
Neuroscience 2017 Sep 30;360:128-138
FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
Huang M, Ma X, Shi H, Hu L, Fan Z, Pang L, Zhu F, Yang X, Xu W, Liu B, Zhu Z, Li C
Oncotarget 2017 Sep 26;8(43):74479-74493
Oncotarget 2017 Sep 26;8(43):74479-74493
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Li X, Jiang Z, Feng J, Zhang X, Wu J, Chen W
Oncotarget 2017 Sep 22;8(37):61846-61860
Oncotarget 2017 Sep 22;8(37):61846-61860
Palladin is a novel microtubule-associated protein responsible for spindle orientation.
Zhang X, Chen X, Liu J, Xu X, Zhang Y, Ruan Z, Xie Y, Huang Q, Yin T, Chen Z, Chen S
Scientific reports 2017 Sep 18;7(1):11806
Scientific reports 2017 Sep 18;7(1):11806
Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice.
Toonen LJA, Rigo F, van Attikum H, van Roon-Mom WMC
Molecular therapy. Nucleic acids 2017 Sep 15;8:232-242
Molecular therapy. Nucleic acids 2017 Sep 15;8:232-242
PKC θ-mediated Ca2+/NF-AT signalling pathway may be involved in T-cell immunosuppression in coal-burning arsenic-poisoned population.
Zeng Q, Luo P, Gu J, Liang B, Liu Q, Zhang A
Environmental toxicology and pharmacology 2017 Oct;55:44-50
Environmental toxicology and pharmacology 2017 Oct;55:44-50
Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.
Zhao P, Zhou R, Zhu XY, Liu G, Zhao YP, Ma PS, Wu W, Niu Y, Sun T, Li YX, Yu JQ, Qian ZM
Neurochemical research 2017 Oct;42(10):2798-2813
Neurochemical research 2017 Oct;42(10):2798-2813
NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit.
Wang W, Yi M, Chen S, Li J, Zhang H, Xiong W, Li G, Li X, Xiang B
Journal of cellular physiology 2017 Oct;232(10):2829-2840
Journal of cellular physiology 2017 Oct;232(10):2829-2840
HIF-1α coordinates epigenetic activation of SIAH1 in hepatocytes in response to nutritional stress.
Fan Z, Li Z, Yang Y, Liu S, Guo J, Xu Y
Biochimica et biophysica acta. Gene regulatory mechanisms 2017 Oct;1860(10):1037-1046
Biochimica et biophysica acta. Gene regulatory mechanisms 2017 Oct;1860(10):1037-1046
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase.
Chang KY, Hsu TI, Hsu CC, Tsai SY, Liu JJ, Chou SW, Liu MS, Liou JP, Ko CY, Chen KY, Hung JJ, Chang WC, Chuang CK, Kao TJ, Chuang JY
Redox biology 2017 Oct;13:655-664
Redox biology 2017 Oct;13:655-664
Inhibition of IL-8-mediated endothelial adhesion, VSMCs proliferation and migration by siRNA-TMEM98 suggests TMEM98's emerging role in atherosclerosis.
Lv G, Zhu H, Li C, Wang J, Zhao D, Li S, Ma L, Sun G, Li F, Zhao Y, Gao Y
Oncotarget 2017 Oct 20;8(50):88043-88058
Oncotarget 2017 Oct 20;8(50):88043-88058
Regulation of m6A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.
Wojtas MN, Pandey RR, Mendel M, Homolka D, Sachidanandam R, Pillai RS
Molecular cell 2017 Oct 19;68(2):374-387.e12
Molecular cell 2017 Oct 19;68(2):374-387.e12
Downregulation of NAD-Dependent Deacetylase SIRT2 Protects Mouse Brain Against Ischemic Stroke.
Xie XQ, Zhang P, Tian B, Chen XQ
Molecular neurobiology 2017 Nov;54(9):7251-7261
Molecular neurobiology 2017 Nov;54(9):7251-7261
Analysis of gene expression and functional characterization of XPR1: a pathogenic gene for primary familial brain calcification.
Yao XP, Zhao M, Wang C, Guo XX, Su HZ, Dong EL, Chen HT, Lai JH, Liu YB, Wang N, Chen WJ
Cell and tissue research 2017 Nov;370(2):267-273
Cell and tissue research 2017 Nov;370(2):267-273
BRAFV600E and RET/PTC Promote Proliferation and Migration of Papillary Thyroid Carcinoma Cells In Vitro by Regulating Nuclear Factor-κB.
Zhou D, Li Z, Bai X
Medical science monitor : international medical journal of experimental and clinical research 2017 Nov 8;23:5321-5329
Medical science monitor : international medical journal of experimental and clinical research 2017 Nov 8;23:5321-5329
Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma.
Chang KY, Huang CT, Hsu TI, Hsu CC, Liu JJ, Chuang CK, Hung JJ, Chang WC, Tsai KK, Chuang JY
Biochemical and biophysical research communications 2017 Nov 4;493(1):14-19
Biochemical and biophysical research communications 2017 Nov 4;493(1):14-19
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
Lorenzo DN, Bennett V
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Wang L, Song G, Zhang X, Feng T, Pan J, Chen W, Yang M, Bai X, Pang Y, Yu J, Han J, Han B
Cancer research 2017 Nov 1;77(21):5755-5768
Cancer research 2017 Nov 1;77(21):5755-5768
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
Zhang X, Fu L, Xue D, Zhang X, Hao F, Xie L, He J, Gai J, Liu Y, Xu H, Li Q, Wang E
Virchows Archiv : an international journal of pathology 2017 May;470(5):553-560
Virchows Archiv : an international journal of pathology 2017 May;470(5):553-560
MicroRNA let-7g possesses a therapeutic potential for peripheral artery disease.
Hsu PY, Hsi E, Wang TM, Lin RT, Liao YC, Juo SH
Journal of cellular and molecular medicine 2017 Mar;21(3):519-529
Journal of cellular and molecular medicine 2017 Mar;21(3):519-529
PTPIP51 regulates mouse cardiac ischemia/reperfusion through mediating the mitochondria-SR junction.
Qiao X, Jia S, Ye J, Fang X, Zhang C, Cao Y, Xu C, Zhao L, Zhu Y, Wang L, Zheng M
Scientific reports 2017 Mar 27;7:45379
Scientific reports 2017 Mar 27;7:45379
Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
Dalet A, Argüello RJ, Combes A, Spinelli L, Jaeger S, Fallet M, Vu Manh TP, Mendes A, Perego J, Reverendo M, Camosseto V, Dalod M, Weil T, Santos MA, Gatti E, Pierre P
The EMBO journal 2017 Mar 15;36(6):761-782
The EMBO journal 2017 Mar 15;36(6):761-782
Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway.
Wang J, Chen X, Tong S, Zhou H, Sun J, Gou Y, Wu F, Hu J, Xu J, Ding G
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317704821
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317704821
JOSD1 Negatively Regulates Type-I Interferon Antiviral Activity by Deubiquitinating and Stabilizing SOCS1.
Wang X, Zhang L, Zhang Y, Zhao P, Qian L, Yuan Y, Liu J, Cheng Q, Xu W, Zuo Y, Guo T, Yu Z, Zheng H
Viral immunology 2017 Jun;30(5):342-349
Viral immunology 2017 Jun;30(5):342-349
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.
Sun S, Liu J, Zhao M, Han Y, Chen P, Mo Q, Wang B, Chen G, Fang Y, Tian Y, Zhou J, Ma D, Gao Q, Wu P
Cell death & disease 2017 Jun 8;8(6):e2870
Cell death & disease 2017 Jun 8;8(6):e2870
Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.
Jiang H, Wang Y, Ai M, Wang H, Duan Z, Wang H, Zhao L, Yu J, Ding Y, Wang S
Cell death & disease 2017 Jun 8;8(6):e2862
Cell death & disease 2017 Jun 8;8(6):e2862
Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Zhang ZH, Wen L, Wu QY, Chen C, Zheng R, Liu Q, Ni JZ, Song GL
Journal of agricultural and food chemistry 2017 Jun 21;65(24):4970-4979
Journal of agricultural and food chemistry 2017 Jun 21;65(24):4970-4979
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
Huijuan W, Xiaoxu C, Rui S, Xinghui L, Beibei T, Jianchun M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:358-365
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:358-365
Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening.
Zhou S, Xiao Y, Zhuang Y, Liu Y, Zhao H, Yang H, Xie C, Zhou F, Zhou Y
Oncology reports 2017 Jul;38(1):515-521
Oncology reports 2017 Jul;38(1):515-521
Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Zhang J, Lu S, Zhou Y, Meng K, Chen Z, Cui Y, Shi Y, Wang T, He QY
Proteomics 2017 Jul;17(13-14)
Proteomics 2017 Jul;17(13-14)
BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells.
Zhang X, Jiang S, Mitok KA, Li L, Attie AD, Martin TFJ
The Journal of cell biology 2017 Jul 3;216(7):2151-2166
The Journal of cell biology 2017 Jul 3;216(7):2151-2166
Anthocyanins from Black Chokeberry (Aroniamelanocarpa Elliot) Delayed Aging-Related Degenerative Changes of Brain.
Wei J, Zhang G, Zhang X, Xu D, Gao J, Fan J, Zhou Z
Journal of agricultural and food chemistry 2017 Jul 26;65(29):5973-5984
Journal of agricultural and food chemistry 2017 Jul 26;65(29):5973-5984
Thymoquinone Attenuates Brain Injury via an Anti-oxidative Pathway in a Status Epilepticus Rat Model.
Shao YY, Li B, Huang YM, Luo Q, Xie YM, Chen YH
Translational neuroscience 2017 Jan;8:9-14
Translational neuroscience 2017 Jan;8:9-14
A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, Wu J, Chang S, Yan Z, Lv Z, Fu J, Liu Y, Jin S, Wang T, Hong T, Dong Y, Ding L, Cheng L, Liu R, Fu S, Jiao S, Ye Q
Nature communications 2017 Jan 17;8:14059
Nature communications 2017 Jan 17;8:14059
Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing.
Zhao J, Sun Y, Huang Y, Song F, Huang Z, Bao Y, Zuo J, Saffen D, Shao Z, Liu W, Wang Y
Scientific reports 2017 Jan 16;7:40488
Scientific reports 2017 Jan 16;7:40488
Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts.
Tsai FJ, Ho TJ, Cheng CF, Shiao YT, Chien WK, Chen JH, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin CW, Lin JG, Lan YC, Liu YH, Hung CH, Lin JC, Lin CC, Lai CH, Liang WM, Lin YJ
Oncotarget 2017 Feb 28;8(9):15470-15489
Oncotarget 2017 Feb 28;8(9):15470-15489
Anthocyanins Delay Ageing-Related Degenerative Changes in the Liver.
Wei J, Zhang G, Zhang X, Xu D, Gao J, Fan J
Plant foods for human nutrition (Dordrecht, Netherlands) 2017 Dec;72(4):425-431
Plant foods for human nutrition (Dordrecht, Netherlands) 2017 Dec;72(4):425-431
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models.
Yu M, Fu Y, Liang Y, Song H, Yao Y, Wu P, Yao Y, Pan Y, Wen X, Ma L, Hexige S, Ding Y, Luo S, Lu B
Cell research 2017 Dec;27(12):1441-1465
Cell research 2017 Dec;27(12):1441-1465
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
Tang Z, Qiu H, Luo L, Liu N, Zhong J, Kang K, Gou D
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
Huang Y, Sun Y, Cao Y, Sun H, Li M, You H, Su D, Li Y, Liang X
Cell death & disease 2017 Dec 11;8(12):3202
Cell death & disease 2017 Dec 11;8(12):3202
Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay.
Sun Y, Bao Y, Han W, Song F, Shen X, Zhao J, Zuo J, Saffen D, Chen W, Wang Z, You X, Wang Y
Nucleic acids research 2017 Aug 21;45(14):8524-8540
Nucleic acids research 2017 Aug 21;45(14):8524-8540
MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5.
Du B, Dai XM, Li S, Qi GL, Cao GX, Zhong Y, Yin PD, Yang XS
Cell death & disease 2017 Aug 10;8(8):e2987
Cell death & disease 2017 Aug 10;8(8):e2987
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Chen L, Chen DQ, Wang M, Liu D, Chen H, Dou F, Vaziri ND, Zhao YY
Chemico-biological interactions 2017 Aug 1;273:56-72
Chemico-biological interactions 2017 Aug 1;273:56-72
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Liu X, Ding S, Shi P, Dietrich R, Märtlbauer E, Zhu K
Cellular microbiology 2017 Apr;19(4)
Cellular microbiology 2017 Apr;19(4)
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
Wang Y, Chu Y, Yue B, Ma X, Zhang G, Xiang H, Liu Y, Wang T, Wu X, Chen B
Oncotarget 2017 Apr 4;8(14):23803-23816
Oncotarget 2017 Apr 4;8(14):23803-23816
MiR-466b-1-3p regulates P-glycoprotein expression in rat cerebral microvascular endothelial cells.
Yang X, Ren W, Shao Y, Chen Y
Neuroscience letters 2017 Apr 3;645:60-66
Neuroscience letters 2017 Apr 3;645:60-66
Vav1 expression is increased in esophageal squamous cell carcinoma and indicates poor prognosis.
Zhu X, Jin H, Xia Z, Wu X, Yang M, Zhang H, Shang X, Cheng R, Zhan Z, Yu Z
Biochemical and biophysical research communications 2017 Apr 29;486(2):571-576
Biochemical and biophysical research communications 2017 Apr 29;486(2):571-576
Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
Chen Y, Yu S, Zhang N, Li Y, Chen S, Chang Y, Sun G, Sun Y
Biochemical and biophysical research communications 2017 Apr 29;486(2):423-430
Biochemical and biophysical research communications 2017 Apr 29;486(2):423-430
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Li Y, You QL, Zhang SR, Huang WY, Zou WJ, Jie W, Li SJ, Liu JH, Lv CY, Cong J, Hu YY, Gao TM, Li JM
Molecular neurobiology 2017 Apr 18;
Molecular neurobiology 2017 Apr 18;
High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.
Chen X, Zhang Q, Luo Y, Gao C, Zhuang X, Xu G, Qiao T
OncoTargets and therapy 2016;9:6511-6518
OncoTargets and therapy 2016;9:6511-6518
Achaete-Scute Homolog 1 Expression Controls Cellular Differentiation of Neuroblastoma.
Kasim M, Heß V, Scholz H, Persson PB, Fähling M
Frontiers in molecular neuroscience 2016;9:156
Frontiers in molecular neuroscience 2016;9:156
Sulforaphane induces apoptosis and inhibits invasion in U251MG glioblastoma cells.
Zhang Z, Li C, Shang L, Zhang Y, Zou R, Zhan Y, Bi B
SpringerPlus 2016;5:235
SpringerPlus 2016;5:235
Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.
Napoli E, Ross-Inta C, Song G, Wong S, Hagerman R, Gane LW, Smilowitz JT, Tassone F, Giulivi C
Frontiers in neuroscience 2016;10:159
Frontiers in neuroscience 2016;10:159
Rabies virus inactivates cofilin to facilitate viral budding and release.
Zan J, An ST, Mo KK, Zhou JW, Liu J, Wang HL, Yan Y, Liao M, Zhou JY
Biochemical and biophysical research communications 2016 Sep 2;477(4):1045-1050
Biochemical and biophysical research communications 2016 Sep 2;477(4):1045-1050
Toll-like receptor 2-mediated MAPKs and NF-κB activation requires the GNAO1-dependent pathway in human mast cells.
Jin M, Yu B, Zhang W, Zhang W, Xiao Z, Mao Z, Lai Y, Lin D, Ma Q, Pan E, Zhang Y, Yu Y
Integrative biology : quantitative biosciences from nano to macro 2016 Sep 12;8(9):968-75
Integrative biology : quantitative biosciences from nano to macro 2016 Sep 12;8(9):968-75
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
Chen L, Zhang F, Sheng XG, Zhang SQ, Chen YT, Liu BW
Oncology reports 2016 Oct;36(4):2135-41
Oncology reports 2016 Oct;36(4):2135-41
NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis.
Shen J, Wang L, Jiang N, Mou S, Zhang M, Gu L, Shao X, Wang Q, Qi C, Li S, Wang W, Che X, Ni Z
Scientific reports 2016 Oct 10;6:34682
Scientific reports 2016 Oct 10;6:34682
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.
Zhang P, Chen L, Song Y, Li X, Sun Y, Xiao Y, Xing Y
Experimental cell research 2016 Oct 1;347(2):350-9
Experimental cell research 2016 Oct 1;347(2):350-9
Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.
Wang N, Guo DY, Tian X, Lin HP, Li YP, Chen SJ, Fu YC, Xu WC, Wei CJ
General and comparative endocrinology 2016 Oct 1;237:98-108
General and comparative endocrinology 2016 Oct 1;237:98-108
Polypeptide N-Acetylgalactosaminyltransferase 13 Contributes to Neurogenesis via Stabilizing the Mucin-type O-Glycoprotein Podoplanin.
Xu Y, Pang W, Lu J, Shan A, Zhang Y
The Journal of biological chemistry 2016 Nov 4;291(45):23477-23488
The Journal of biological chemistry 2016 Nov 4;291(45):23477-23488
Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies.
Kovalevich J, Cornec AS, Yao Y, James M, Crowe A, Lee VM, Trojanowski JQ, Smith AB 3rd, Ballatore C, Brunden KR
The Journal of pharmacology and experimental therapeutics 2016 May;357(2):432-50
The Journal of pharmacology and experimental therapeutics 2016 May;357(2):432-50
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Wen Q, Wang W, Luo J, Chu S, Chen L, Xu L, Zang H, Alnemah MM, Ma J, Fan S
Oncotarget 2016 May 10;7(19):27787-801
Oncotarget 2016 May 10;7(19):27787-801
Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.
Bai Y, Shang Q, Zhao H, Pan Z, Guo C, Zhang L, Wang Q
Cell death & disease 2016 Mar 31;7:e2169
Cell death & disease 2016 Mar 31;7:e2169
Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.
Yin Y, Liu L, Yang C, Lin C, Veith GM, Wang C, Sutovsky P, Zhou P, Ma L
The Journal of biological chemistry 2016 Mar 25;291(13):6923-35
The Journal of biological chemistry 2016 Mar 25;291(13):6923-35
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Yin J, Lu Z, Wang F, Jiang Z, Lu L, Miao N, Wang N
Journal of cellular and molecular medicine 2016 Jun;20(6):1106-17
Journal of cellular and molecular medicine 2016 Jun;20(6):1106-17
Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells.
Yu Y, Huang Z, Mao Z, Zhang Y, Jin M, Chen W, Zhang W, Yu B, Zhang W, Alaster Lau HY
European journal of pharmacology 2016 Jun 5;780:115-21
European journal of pharmacology 2016 Jun 5;780:115-21
Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochlea.
Jin Y, Ren N, Li S, Fu X, Sun X, Men Y, Xu Z, Zhang J, Xie Y, Xia M, Gao J
Scientific reports 2016 Jun 3;6:27124
Scientific reports 2016 Jun 3;6:27124
miR-1301 promotes prostate cancer proliferation through directly targeting PPP2R2C.
Bi D, Ning H, Liu S, Que X, Ding K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Jul;81:25-30
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Jul;81:25-30
MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2.
Zhang Y, Chen M, Qiu Z, Hu K, McGee W, Chen X, Liu J, Zhu L, Wu JY
Protein & cell 2016 Jul;7(7):489-500
Protein & cell 2016 Jul;7(7):489-500
Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells.
Yan M, Qian YM, Yue CF, Wang ZF, Wang BC, Zhang W, Zheng FM, Liu Q
Oncotarget 2016 Jul 12;7(28):44171-44184
Oncotarget 2016 Jul 12;7(28):44171-44184
PfIRR Interacts with HrIGF-I and Activates the MAP-kinase and PI3-kinase Signaling Pathways to Regulate Glycogen Metabolism in Pinctada fucata.
Shi Y, He MX
Scientific reports 2016 Feb 25;6:22063
Scientific reports 2016 Feb 25;6:22063
Nogo-B receptor promotes the chemoresistance of human hepatocellular carcinoma via the ubiquitination of p53 protein.
Dong C, Zhao B, Long F, Liu Y, Liu Z, Li S, Yang X, Sun D, Wang H, Liu Q, Liang R, Li Y, Gao Z, Shao S, Miao QR, Wang L
Oncotarget 2016 Feb 23;7(8):8850-65
Oncotarget 2016 Feb 23;7(8):8850-65
Spatially coordinated dynamic gene transcription in living pituitary tissue.
Featherstone K, Hey K, Momiji H, McNamara AV, Patist AL, Woodburn J, Spiller DG, Christian HC, McNeilly AS, Mullins JJ, Finkenstädt BF, Rand DA, White MR, Davis JR
eLife 2016 Feb 1;5:e08494
eLife 2016 Feb 1;5:e08494
Anxa5 mediates the in vitro malignant behaviours of murine hepatocarcinoma Hca-F cells with high lymph node metastasis potential preferentially via ERK2/p-ERK2/c-Jun/p-c-Jun(Ser73) and E-cadherin.
Sun X, Wei B, Liu S, Guo C, Wu N, Liu Q, Sun MZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:645-654
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:645-654
Protective Effects of Thymoquinone Against Convulsant Activity Induced by Lithium-Pilocarpine in a model of Status Epilepticus.
Shao Y, Feng Y, Xie Y, Luo Q, Chen L, Li B, Chen Y
Neurochemical research 2016 Dec;41(12):3399-3406
Neurochemical research 2016 Dec;41(12):3399-3406
Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats.
Zhang Y, Li RM, Wang C, Liu N, Lv S, Xiong JY
Molecular medicine reports 2016 Dec;14(6):5760-5766
Molecular medicine reports 2016 Dec;14(6):5760-5766
SUMOylated MAFB promotes colorectal cancer tumorigenesis.
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Oncotarget 2016 Dec 13;7(50):83488-83501
Oncotarget 2016 Dec 13;7(50):83488-83501
Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity.
Wu J, Guo W, Lin SZ, Wang ZJ, Kan JT, Chen SY, Zhu YZ
Cell death & disease 2016 Aug 18;7(8):e2339
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Scientific reports 2016 Apr 7;6:24226
Scientific reports 2016 Apr 7;6:24226
ZBTB20 is required for anterior pituitary development and lactotrope specification.
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Nature communications 2016 Apr 15;7:11121
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Real Time Monitoring of Inhibition of Adipogenesis and Angiogenesis by (-)-Epigallocatechin-3-Gallate in 3T3-L1 Adipocytes and Human Umbilical Vein Endothelial Cells.
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Nutrients 2015 Oct 27;7(10):8871-86
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Scientific reports 2015 Mar 9;5:8895
Scientific reports 2015 Mar 9;5:8895
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Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells.
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Scientific reports 2015 Jul 13;5:12098
Scientific reports 2015 Jul 13;5:12098
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MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
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Molecular endocrinology (Baltimore, Md.) 2010 Apr;24(4):800-12
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The Journal of biological chemistry 2008 Nov 21;283(47):32660-8
The Journal of biological chemistry 2008 Nov 21;283(47):32660-8
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- Western blot of Hela cell with anti-Tubulin-Alpha (11224-1-AP) at various dilutions.
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The alpha Tubulin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human alpha Tubulin. This antibody recognizes human,mouse,rat antigen. The alpha Tubulin antibody has been validated for the following applications: ELISA, WB, IP, IHC, IF analysis.
Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells using 11224-1-AP( Tubulin-Alpha Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-Tubulin-Alpha (IP:11224-1-AP, 3ug; Detection:11224-1-AP 1:1000) with HeLa cells lysate 5000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11224-1-AP(Tubulin-Alpha antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11224-1-AP(Tubulin-Alpha antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
