BS8775

antibody from Bioworld Technology, Inc
Targeting: PHIP BRWD2, DCAF14, FLJ20705, ndrp, WDR11
Provider product page for BS8775
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8775 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PHIP polyclonal antibody
Antibody type
Polyclonal
Antigen
PH-interacting protein; PHIP; IRS-1 PH domain-binding protein; WD repeat-containing protein 11; PHIP; WDR11
Description
PHIP (pleckstrin homology domain interacting protein), also known as ndrp or WDR11, is a 1,821 amino acid protein that contains eight N-terminal WD40 repeats and two bromodomains. It is expressed in skeletal muscle (localizing to the cytosol and nucleus) and primary ÉÇ cells (localizing to the nucleus) and acts as a transcriptional activator. PHIP is known to interact with various members of the insulin receptor substrate (IRS) family. The IRS family of proteins mediate insulin receptor signaling and play an important role in insulin-producing ÉÇ cell proliferation and survival. PHIP specifically associates with the PH domain of IRS-1 and may function to link IRS-1 to insulin receptors, indicating a vital role of PHIP in the regulation of insulin signaling.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PHIP protein structure - BS8775 shown in red.