BS8265

antibody from Bioworld Technology, Inc
Targeting: HPD 4-HPPD, 4HPPD, GLOD3, PPD
Provider product page for BS8265
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8265 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HPD polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HPD.
Description
HPPD (4-hydroxyphenylpyruvate dioxygenase), also known as PPD, GLOD3 or HPD, is a 393 amino acid protein that belongs to the 4HPPD family and is involved in amino acid degradation. Existing as a homodimer, HPPD uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. Defects in the gene encoding HPPD are the cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK), both of which are inborn errors of metabolism that are associated with a variety of symptoms, including mental retardation and seizures (associated with TYRO3) and hair and urine abnormalities (associated with HAWK). The gene encoding HPPD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HPD protein structure - BS8265 shown in red.