APG01156G

antibody from Leading Biology

Targeting: AGO1 EIF2C1, hAGO1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APG01156G

Provider

Leading Biology

Product name

AGO1 / EIF2C Antibody (Internal)

Antibody type

Polyclonal

Description

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).

Reactivity

Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Hamster, Horse, Porcine, Rabbit, Simian, Xenopus

Host

Goat

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.