AMM02926G

antibody from Leading Biology

Targeting: CFAP251 CaM-IP4, MGC33630, WDR66

Western blot (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

AMM02926G

Provider

Leading Biology

Product name

WDR66 Antibody

Antibody type

Monoclonal

Description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. ;

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

2A6F7

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.