FNab09760

antibody from FineTest Biotech

Targeting: ZW10 KNTC1AP

Western blot

ELISA

Immunoprecipitation

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Validation data

Product number: FNab09760 - Provider product page
Provider: FineTest Biotech
Product name: ZW10 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum(ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER(PubMed:15029241).
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: ZW10, kinetochore associated, homol og(Drosophila)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ZW10 protein structure - FNab09760 shown in red.