DPABH-13797

antibody from Creative Diagnostics

Targeting: SETX ALS4, AOA2, KIAA0625, SCAR1, Sen1

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

DPABH-13797

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-13797, RRID:AB_2512612

Product name

Rabbit Anti-Human SETX Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Concentration

Lot specific

Storage

2 - 8° C. 1 year from date of receipt