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- Product number
- ABIN252880 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Senataxin (SETX) (AA 875-925) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 875-925
- Isotype
- IgG
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1.
A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage.
Nguyen HD, Yadav T, Giri S, Saez B, Graubert TA, Zou L
Molecular cell 2017 Mar 2;65(5):832-847.e4
Molecular cell 2017 Mar 2;65(5):832-847.e4
A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage.
Richard P, Feng S, Manley JL
Genes & development 2013 Oct 15;27(20):2227-32
Genes & development 2013 Oct 15;27(20):2227-32
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Supportive validation
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