CABT-BL3600

antibody from Creative Diagnostics

Targeting: TMEM123 KCT3, PORIMIN

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-BL3600

Provider

Creative Diagnostics

Product name

Anti-TMEM123 monoclonal antibody, clone 2G5

Antibody type

Monoclonal

Description

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2G5

Storage

Store at -2°C or lower. Aliquot to avoid repeated freezing and thawing.