BS8294

antibody from Bioworld Technology, Inc
Targeting: GPAM GPAT1, KIAA1560, MGC26846
Provider product page for BS8294
Western blot
Immunohistochemistry

Antibody data

Product number
BS8294 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GPAM polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GPAM.
Description
GPAM (glycerol-3-phosphate acyltransferase, mitochondrial), also known as GPAT1, GPAT or KIAA1560, is an 828 amino acid multi-pass membrane protein that localizes to the outer membrane of the mitochondria and is involved in phospholipid metabolism. More specifically, GPAM functions to catalyze the first and committing step in the biosynthesis of glycerolipid, namely the conversion of Acyl-CoA and sn-glycerol 3-phosphate to CoA and 1-acyl-sn-glycerol 3-phosphate. Via its catalytic activity, GPAM plays an essential role in the regulation of cellular triacylglycerol and phospholipid levels. The gene encoding GPAM maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman£ªs syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GPAM protein structure - BS8294 shown in red.