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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB3313 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3313, RRID:AB_1579123
- Product name
- PRKAR1A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PRKAR1A.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity.
Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.
Human tumors associated with Carney complex and germline PRKAR1A mutations: a protein kinase A disease!
Bertherat J, Groussin L, Sandrini F, Matyakhina L, Bei T, Stergiopoulos S, Papageorgiou T, Bourdeau I, Kirschner LS, Vincent-Dejean C, Perlemoine K, Gicquel C, Bertagna X, Stratakis CA
Cancer research 2003 Sep 1;63(17):5308-19
Cancer research 2003 Sep 1;63(17):5308-19
Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.
Grönholm M, Vossebein L, Carlson CR, Kuja-Panula J, Teesalu T, Alfthan K, Vaheri A, Rauvala H, Herberg FW, Taskén K, Carpén O
The Journal of biological chemistry 2003 Oct 17;278(42):41167-72
The Journal of biological chemistry 2003 Oct 17;278(42):41167-72
Human tumors associated with Carney complex and germline PRKAR1A mutations: a protein kinase A disease!
Stergiopoulos SG, Stratakis CA
FEBS letters 2003 Jul 3;546(1):59-64
FEBS letters 2003 Jul 3;546(1):59-64
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of PRKAR1A polyclonal antibody (Cat # PAB3313) in Jurkat cell lysate. PRKAR1A (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with PRKAR1A polyclonal antibody (Cat # PAB3313) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
