Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN500780 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Snail Homolog 2 (Drosophila) (SNAI2) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- Slug antibody was raised against a 13 amino acid peptide from near the center of human Slug.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells.
Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients.
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma.
Control of cell behavior during vertebrate development by Slug, a zinc finger gene.
Martínez-Estrada OM, Cullerés A, Soriano FX, Peinado H, Bolós V, Martínez FO, Reina M, Cano A, Fabre M, Vilaró S
The Biochemical journal 2006 Mar 1;394(Pt 2):449-57
The Biochemical journal 2006 Mar 1;394(Pt 2):449-57
Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients.
Shioiri M, Shida T, Koda K, Oda K, Seike K, Nishimura M, Takano S, Miyazaki M
British journal of cancer 2006 Jun 19;94(12):1816-22
British journal of cancer 2006 Jun 19;94(12):1816-22
Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma.
Wu WS, Heinrichs S, Xu D, Garrison SP, Zambetti GP, Adams JM, Look AT
Cell 2005 Nov 18;123(4):641-53
Cell 2005 Nov 18;123(4):641-53
Control of cell behavior during vertebrate development by Slug, a zinc finger gene.
Nieto MA, Sargent MG, Wilkinson DG, Cooke J
Science (New York, N.Y.) 1994 May 6;264(5160):835-9
Science (New York, N.Y.) 1994 May 6;264(5160):835-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Slug in 293 cell lysate with AP30813PU-N at in (A) 0.5, (B) 1 and (C) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of Slug in human kidney tissue with AP30813PU-N at 20 ?g/ml.