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- References [10]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 11028-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11028-2-AP, RRID:AB_2294066
- Product name
- FHL3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FHL3 antibody (Cat. #11028-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FHL3 Contributes to EMT and Chemotherapy Resistance Through Up-Regulation of Slug and Activation of TGFβ/Smad-Independent Pathways in Gastric Cancer.
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
FHL3 links cell growth and self-renewal by modulating SOX4 in glioma.
A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Identification and characterization of MT-1X as a novel FHL3-binding partner.
Ribotrap analysis of proteins associated with FHL3 3'untranslated region in glioma cells.
RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3.
The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoprotein.
FHL family members suppress vascular endothelial growth factor expression through blockade of dimerization of HIF1α and HIF1β.
Identification and characterization of FHL3 as a novel angiogenin-binding partner.
Cao G, Li P, He X, Jin M, Li M, Chen S, Xu X, Sun Q, Xiong M, Chen B
Frontiers in oncology 2021;11:649029
Frontiers in oncology 2021;11:649029
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
Li P, Cao G, Zhang Y, Shi J, Cai K, Zhen L, He X, Zhou Y, Li Y, Zhu Y, Xiong M, Wu Y
Aging 2020 Jan 13;12(1):53-69
Aging 2020 Jan 13;12(1):53-69
FHL3 links cell growth and self-renewal by modulating SOX4 in glioma.
Han W, Hu P, Wu F, Wang S, Hu Y, Li S, Jiang T, Qiang B, Peng X
Cell death and differentiation 2019 May;26(5):796-811
Cell death and differentiation 2019 May;26(5):796-811
A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, Wu J, Chang S, Yan Z, Lv Z, Fu J, Liu Y, Jin S, Wang T, Hong T, Dong Y, Ding L, Cheng L, Liu R, Fu S, Jiao S, Ye Q
Nature communications 2017 Jan 17;8:14059
Nature communications 2017 Jan 17;8:14059
Identification and characterization of MT-1X as a novel FHL3-binding partner.
Cai X, Wang J, Huang X, Fu W, Xia W, Zou M, Wang Y, Wang J, Xu D
PloS one 2014;9(4):e93723
PloS one 2014;9(4):e93723
Ribotrap analysis of proteins associated with FHL3 3'untranslated region in glioma cells.
Han W, Xia Q, Yin B, Peng XZ
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 2014 Jun;29(2):78-84
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 2014 Jun;29(2):78-84
RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3.
Han W, Xin Z, Zhao Z, Bao W, Lin X, Yin B, Zhao J, Yuan J, Qiang B, Peng X
The Journal of clinical investigation 2013 May;123(5):2103-18
The Journal of clinical investigation 2013 May;123(5):2103-18
The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoprotein.
McCabe Á, Hashimoto K, Hall WW, Sheehy N
Journal of virology 2013 Jul;87(13):7435-44
Journal of virology 2013 Jul;87(13):7435-44
FHL family members suppress vascular endothelial growth factor expression through blockade of dimerization of HIF1α and HIF1β.
Lin J, Qin X, Zhu Z, Mu J, Zhu L, Wu K, Jiao H, Xu X, Ye Q
IUBMB life 2012 Nov;64(11):921-30
IUBMB life 2012 Nov;64(11):921-30
Identification and characterization of FHL3 as a novel angiogenin-binding partner.
Xia W, Fu W, Cai L, Kong H, Cai X, Liu J, Wang Y, Zou M, Xu D
Gene 2012 Aug 10;504(2):233-7
Gene 2012 Aug 10;504(2):233-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 11028-2-AP(FHL3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 11028-2-AP(FHL3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FHL3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FHL3. This antibody recognizes human, mouse, rat antigen. The FHL3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
