Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 13838-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13838-1-AP, RRID:AB_2199812
- Product name
- TCF4/TCF7L2 antibody
- Antibody type
- Polyclonal
- Description
- TCF4/TCF7L2 antibody (Cat. #13838-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MicroRNA-22-3p targeted regulating transcription factor 7-like 2 (TCF7L2) constrains the Wnt/β-catenin pathway and malignant behavior in osteosarcoma.
Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells in vitro by Forming a Complex With Tcf4 and β-Catenin.
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Ginsenoside Rg1 Improves Differentiation by Inhibiting Senescence of Human Bone Marrow Mesenchymal Stem Cell via GSK-3β and β-Catenin.
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Computational and functional analyses of T2D GWAS SNPs for transcription factor binding.
Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells.
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Smad6 suppresses the growth and self-renewal of hepatic progenitor cells.
Xue Y, Guo Y, Liu N, Deng Z, Jian Y, Cai H, Meng X
Bioengineered 2021 Nov 10;
Bioengineered 2021 Nov 10;
Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells in vitro by Forming a Complex With Tcf4 and β-Catenin.
Yu N, Hu T, Yang H, Zhang L, Song Q, Xiang F, Yang X, Li Y
Frontiers in cell and developmental biology 2020;8:824
Frontiers in cell and developmental biology 2020;8:824
Modulation of Wnt/β-catenin signaling in IL-17A-mediated macrophage polarization of RAW264.7 cells.
Yuan C, Yang D, Ma J, Yang J, Xue J, Song F, Liu X
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2020;53(8):e9488
Ginsenoside Rg1 Improves Differentiation by Inhibiting Senescence of Human Bone Marrow Mesenchymal Stem Cell via GSK-3β and β-Catenin.
Wang Z, Jiang R, Wang L, Chen X, Xiang Y, Chen L, Xiao M, Ling L, Wang Y
Stem cells international 2020;2020:2365814
Stem cells international 2020;2020:2365814
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Li S, Liu F, Xu L, Li C, Yang X, Guo B, Gu J, Wang L
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.
Li K, Zhang J, Tian Y, He Y, Xu X, Pan W, Gao Y, Chen F, Wei L
Oncogene 2020 Mar;39(11):2258-2274
Oncogene 2020 Mar;39(11):2258-2274
Computational and functional analyses of T2D GWAS SNPs for transcription factor binding.
Cheng M, Huang X, Zhang M, Huang Q
Biochemical and biophysical research communications 2020 Mar 12;523(3):658-665
Biochemical and biophysical research communications 2020 Mar 12;523(3):658-665
Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.
Jiang J, Fan Y, Zhang W, Shen Y, Liu T, Yao M, Gu J, Tu H, Gan Y
International journal of biological sciences 2019;15(2):253-264
International journal of biological sciences 2019;15(2):253-264
Stimulation of endothelial progenitor cells by microRNA-31a-5p to induce endothelialization in an aneurysm neck after coil embolization by modulating the Axin1-mediated β-catenin/vascular endothelial growth factor pathway.
Yu G, Liu P, Shi Y, Li S, Liu Y, Fan Z, Zhu W
Journal of neurosurgery 2019 Aug 9;:1-9
Journal of neurosurgery 2019 Aug 9;:1-9
miR-10b promoted melanoma progression through Wnt/β-catenin pathway by repressing ITCH expression.
Wang S, Wu Y, Xu Y, Tang X
Gene 2019 Aug 20;710:39-47
Gene 2019 Aug 20;710:39-47
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells.
Wang X, Su GY, Zhao C, Qu FZ, Wang P, Zhao YQ
Journal of ginseng research 2018 Apr;42(2):133-143
Journal of ginseng research 2018 Apr;42(2):133-143
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
Chen Y, Pan K, Wang P, Cao Z, Wang W, Wang S, Hu N, Xue J, Li H, Jiang W, Li G, Zhang X
The Journal of biological chemistry 2016 Jun 10;291(24):12688-12705
The Journal of biological chemistry 2016 Jun 10;291(24):12688-12705
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, Fei Y, Li C
Scientific reports 2016 Apr 25;6:24859
Scientific reports 2016 Apr 25;6:24859
Smad6 suppresses the growth and self-renewal of hepatic progenitor cells.
Ding ZY, Liang HF, Jin GN, Chen WX, Wang W, Datta PK, Zhang MZ, Zhang B, Chen XP
Journal of cellular physiology 2014 May;229(5):651-60
Journal of cellular physiology 2014 May;229(5):651-60
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The TCF7L2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TCF7L2. This antibody recognizes human, mouse, rat antigen. The TCF7L2 antibody has been validated for the following applications: ELISA, WB analysis.