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- Product number
- ABIN393981 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-597) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 490-597
- Isotype
- IgG
- Antibody clone number
- 1A1
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from the International Association of Diabetes and Pregnancy Study Groups.
Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion.
Potential role of TCF7L2 gene variants on cardiac sympathetic/parasympathetic activity.
The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3beta-independent manner.
Kucharska-Newton AM, Monda KL, Bielinski SJ, Boerwinkle E, Rea TD, Rosamond WD, Pankow JS, Köttgen A, Heiss G, North KE
Journal of obesity 2010;2010
Journal of obesity 2010;2010
Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from the International Association of Diabetes and Pregnancy Study Groups.
Freathy RM, Hayes MG, Urbanek M, Lowe LP, Lee H, Ackerman C, Frayling TM, Cox NJ, Dunger DB, Dyer AR, Hattersley AT, Metzger BE, Lowe WL Jr, HAPO Study Cooperative Research Group.
Diabetes 2010 Oct;59(10):2682-9
Diabetes 2010 Oct;59(10):2682-9
Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion.
Heni M, Ketterer C, Thamer C, Herzberg-Schäfer SA, Guthoff M, Stefan N, Machicao F, Staiger H, Fritsche A, Häring HU
Diabetes 2010 Dec;59(12):3247-52
Diabetes 2010 Dec;59(12):3247-52
Potential role of TCF7L2 gene variants on cardiac sympathetic/parasympathetic activity.
Boccardi V, Ambrosino I, Papa M, Fiore D, Rizzo MR, Paolisso G, Barbieri M
European journal of human genetics : EJHG 2010 Dec;18(12):1333-8
European journal of human genetics : EJHG 2010 Dec;18(12):1333-8
The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3beta-independent manner.
Struewing I, Boyechko T, Barnett C, Beildeck M, Byers SW, Mao CD
Biochemical and biophysical research communications 2010 Aug 20;399(2):245-50
Biochemical and biophysical research communications 2010 Aug 20;399(2):245-50
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