Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Flow cytometry [2]
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Validation data
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- Product number
- FAB3478A-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CCR10 APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detect human CCR10. Stains human CCR10-transfected cells but not irrelevant transfectants.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Red dye
- Antigen sequence
P46092
- Isotype
- IgG
- Antibody clone number
- 314305
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells.
A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa.
Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica.
Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab.
CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells.
Karnezis T, Farnsworth RH, Harris NC, Williams SP, Caesar C, Byrne DJ, Herle P, Macheda ML, Shayan R, Zhang YF, Yazar S, Takouridis SJ, Gerard C, Fox SB, Achen MG, Stacker SA
Cancer research 2019 Apr 1;79(7):1558-1572
Cancer research 2019 Apr 1;79(7):1558-1572
A role for CCL28-CCR3 in T-cell homing to the human upper airway mucosa.
Danilova E, Skrindo I, Gran E, Hales BJ, Smith WA, Jahnsen J, Johansen FE, Jahnsen FL, Baekkevold ES
Mucosal immunology 2015 Jan;8(1):107-14
Mucosal immunology 2015 Jan;8(1):107-14
Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica.
Chihara N, Aranami T, Oki S, Matsuoka T, Nakamura M, Kishida H, Yokoyama K, Kuroiwa Y, Hattori N, Okamoto T, Murata M, Toda T, Miyake S, Yamamura T
PloS one 2013;8(12):e83036
PloS one 2013;8(12):e83036
Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab.
Mei HE, Frölich D, Giesecke C, Loddenkemper C, Reiter K, Schmidt S, Feist E, Daridon C, Tony HP, Radbruch A, Dörner T
Blood 2010 Dec 9;116(24):5181-90
Blood 2010 Dec 9;116(24):5181-90
CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells.
Hansson M, Hermansson M, Svensson H, Elfvin A, Hansson LE, Johnsson E, Sjöling A, Quiding-Järbrink M
Infection and immunity 2008 Jul;76(7):3304-11
Infection and immunity 2008 Jul;76(7):3304-11
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB100F) and either (A) Rat Anti-Human CCR10 APC-conjugated Monoclonal Antibody (Catalog # FAB3478A) or (B) Rat IgG2A Allophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR10 in L1.2 Mouse Cell Line Transfected with Human CCR10 and eGFP by Flow Cytometry. L1.2 mouse pro-B cell line transfected with human CCR10 and eGFP was stained with either (A) Rat IgG2A Allophycocyanin Isotype Control (Catalog # IC006A) or (B) Rat Anti-Human CCR10 APC-conjugated Monoclonal Antibody (Catalog # FAB3478A). View our protocol for Staining Membrane-associated Proteins.