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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Flow cytometry [2]
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- Product number
- FAB3478P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CCR10 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detect human CCR10. Stains human CCR10-transfected cells but not irrelevant transfectants.
- Reactivity
- Human
- Host
- Rat
- Antigen sequence
P46092- Isotype
- IgG
- Antibody clone number
- 314305
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Skewing toward Treg and Th2 responses is a characteristic feature of sustained remission in ANCA-positive granulomatosis with polyangiitis.
Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity.
Functional Langerinhigh-Expressing Langerhans-like Cells Can Arise from CD14highCD16- Human Blood Monocytes in Serum-Free Condition.
Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
The oral commensal Streptococcus mitis shows a mixed memory Th cell signature that is similar to and cross-reactive with Streptococcus pneumoniae.
CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation.
Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation.
IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells.
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells.
Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis.
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab.
Szczeklik W, Jakieła B, Wawrzycka-Adamczyk K, Sanak M, Hubalewska-Mazgaj M, Padjas A, Surmiak M, Szczeklik K, Sznajd J, Musiał J
European journal of immunology 2017 Apr;47(4):724-733
European journal of immunology 2017 Apr;47(4):724-733
Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity.
Maghazachi AA, Sand KL, Al-Jaderi Z
Frontiers in immunology 2016;7:437
Frontiers in immunology 2016;7:437
Functional Langerinhigh-Expressing Langerhans-like Cells Can Arise from CD14highCD16- Human Blood Monocytes in Serum-Free Condition.
Picarda G, Chéneau C, Humbert JM, Bériou G, Pilet P, Martin J, Duteille F, Perrot P, Bellier-Waast F, Heslan M, Haspot F, Guillon F, Josien R, Halary FA
Journal of immunology (Baltimore, Md. : 1950) 2016 May 1;196(9):3716-28
Journal of immunology (Baltimore, Md. : 1950) 2016 May 1;196(9):3716-28
Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
Faulkner L, Gibson A, Sullivan A, Tailor A, Usui T, Alfirevic A, Pirmohamed M, Naisbitt DJ, Kevin Park B
Toxicological sciences : an official journal of the Society of Toxicology 2016 Dec;154(2):416-429
Toxicological sciences : an official journal of the Society of Toxicology 2016 Dec;154(2):416-429
The oral commensal Streptococcus mitis shows a mixed memory Th cell signature that is similar to and cross-reactive with Streptococcus pneumoniae.
Engen SA, Valen Rukke H, Becattini S, Jarrossay D, Blix IJ, Petersen FC, Sallusto F, Schenck K
PloS one 2014;9(8):e104306
PloS one 2014;9(8):e104306
CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation.
Buckner CM, Moir S, Kardava L, Ho J, Santich BH, Kim LJ, Funk EK, Nelson AK, Winckler B, Chairez CL, Theobald-Whiting NL, Anaya-O'Brien S, Alimchandani M, Quezado MM, Yao MD, Kovacs JA, Chun TW, Fauci AS, Malech HL, De Ravin SS
The Journal of allergy and clinical immunology 2014 Jun;133(6):1676-85.e5
The Journal of allergy and clinical immunology 2014 Jun;133(6):1676-85.e5
Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation.
Pinto S, Martínez-Romero A, O'Connor JE, Gil-Benso R, San-Miguel T, Terrádez L, Monteagudo C, Callaghan RC
BMC cancer 2014 Feb 22;14:118
BMC cancer 2014 Feb 22;14:118
IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells.
Tang XZ, Jo J, Tan AT, Sandalova E, Chia A, Tan KC, Lee KH, Gehring AJ, De Libero G, Bertoletti A
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 1;190(7):3142-52
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 1;190(7):3142-52
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells.
Duhen T, Duhen R, Lanzavecchia A, Sallusto F, Campbell DJ
Blood 2012 May 10;119(19):4430-40
Blood 2012 May 10;119(19):4430-40
Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis.
Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T
Clinical and experimental immunology 2011 Feb;163(2):215-24
Clinical and experimental immunology 2011 Feb;163(2):215-24
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Carbone T, Nasorri F, Pennino D, Eyerich K, Foerster S, Cifaldi L, Traidl-Hoffman C, Behrendt H, Cavani A
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab.
Mei HE, Frölich D, Giesecke C, Loddenkemper C, Reiter K, Schmidt S, Feist E, Daridon C, Tony HP, Radbruch A, Dörner T
Blood 2010 Dec 9;116(24):5181-90
Blood 2010 Dec 9;116(24):5181-90
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon APC-conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Rat Anti-Human CCR10 PE-conjugated Monoclonal Antibody (Catalog # FAB3478P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CCR10 in L1.2 Mouse Cell Line Transfected with Human CCR10 and eGFP by Flow Cytometry. L1.2 mouse pro-B cell line transfected with human CCR10 and eGFP was stained with either (A) Rat Anti-Human CCR10 PE-conjugated Monoclonal Antibody (Catalog # FAB3478P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
