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LearnNB400-104
antibody from Novus Biologicals
Targeting: SCARB1
CD36L1, CLA-1, CLA1, SR-BI, SRB1
Western blot
Immunocytochemistry Immunoprecipitation Immunohistochemistry Flow cytometry Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [196]
- Comments [0]
- Validations
- Western blot [4]
- Immunohistochemistry [4]
- Flow cytometry [6]
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- Product number
- NB400-104 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB400-104, RRID:AB_2182824
- Product name
- Rabbit Polyclonal SR-BI Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Hamster, Porcine, Rabbit, Simian
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation.
Serum amyloid A is not incorporated into HDL during HDL biogenesis.
Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.
Soraphen A enhances macrophage cholesterol efflux via indirect LXR activation and ABCA1 upregulation.
Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice.
MicroRNA-205-5p Promotes Unstable Atherosclerotic Plaque Formation In Vivo.
SR-BI Interactome Analysis Reveals a Proviral Role for UGGT1 in Hepatitis C Virus Entry.
High soluble endoglin levels regulate cholesterol homeostasis and bile acids turnover in the liver of transgenic mice.
Phagocytosis mediated by scavenger receptor class BI promotes macrophage transition during skeletal muscle regeneration.
SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis.
Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I.
Upregulation of Scavenger Receptor B1 Is Required for Steroidogenic and Nonsteroidogenic Cholesterol Metabolism in Prostate Cancer.
Prenatal exposure to valproate induces sex-, age-, and tissue-dependent alterations of cholesterol metabolism: Potential implications on autism.
Endoplasmic Reticulum Stress Affects Lipid Metabolism in Atherosclerosis Via CHOP Activation and Over-Expression of miR-33.
A role for scavenger receptor B1 as a captor of specific fatty acids in taste buds of circumvallate papillae.
A novel role for scavenger receptor B1 as a contributor to the capture of specific volatile odorants in the nasal cavity.
Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet.
Apolipoprotein B-100 peptide 210 antibody inhibits atherosclerosis by regulation of macrophages that phagocytize oxidized lipid.
Experimental challenges regarding the in vitro investigation of the nanoparticle-biocorona in disease states.
SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo.
Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells.
Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice.
Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell-derived hepatocytes.
Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs "in vitro" wound closure.
Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells.
6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages.
Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.
Novel interactomics approach identifies ABCA1 as direct target of evodiamine, which increases macrophage cholesterol efflux.
A novel immortalized hepatocyte-like cell line (imHC) supports in vitro liver stage development of the human malarial parasite Plasmodium vivax.
HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner.
Cholesterol metabolism and Cx43, Cx46, and Cx50 gap junction protein expression and localization in normal and diabetic and obese ob/ob and db/db mouse testes.
Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding.
Altered Brain Cholesterol/Isoprenoid Metabolism in a Rat Model of Autism Spectrum Disorders.
High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2.
FoxO transcription factors are required for hepatic HDL cholesterol clearance.
SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1.
HCV replication in gastrointestinal mucosa: Potential extra-hepatic viral reservoir and possible role in HCV infection recurrence after liver transplantation.
Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages.
Rational Targeting of Cellular Cholesterol in Diffuse Large B-Cell Lymphoma (DLBCL) Enabled by Functional Lipoprotein Nanoparticles: A Therapeutic Strategy Dependent on Cell of Origin.
LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis.
Impact of dietary phytol on lipid metabolism in SCP2/SCPX/L-FABP null mice.
The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells.
Deconstructing Olfactory Stem Cell Trajectories at Single-Cell Resolution.
Activation of liver X receptor suppresses angiogenesis via induction of ApoD.
Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages.
Apolipoprotein A-II Plus Lipid Emulsion Enhance Cell Growth via SR-B1 and Target Pancreatic Cancer In Vitro and In Vivo.
A New Signaling Pathway for HCV Inhibition by Estrogen: GPR30 Activation Leads to Cleavage of Occludin by MMP-9.
Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice.
A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection.
The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis.
ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer.
Up-regulated expression of scavenger receptor class B type 1 (SR-B1) is associated with malignant behaviors and poor prognosis of breast cancer.
High-density lipoprotein inhibits ox-LDL-induced adipokine secretion by upregulating SR-BI expression and suppressing ER Stress pathway.
Lanatoside C Promotes Foam Cell Formation and Atherosclerosis.
Difference in expression patterns of placental cholesterol transporters, ABCA1 and SR-BI, in Meishan and Yorkshire pigs with different placental efficiency.
CD36 is a co-receptor for hepatitis C virus E1 protein attachment.
Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells.
MicroRNA-192* impairs adipocyte triglyceride storage.
Impact of Silver and Iron Nanoparticle Exposure on Cholesterol Uptake by Macrophages.
A Novel Anti-Inflammatory Effect for High Density Lipoprotein.
Coenzyme Q10 consumption promotes ABCG1-mediated macrophage cholesterol efflux: a randomized, double-blind, placebo-controlled, cross-over study in healthy volunteers.
Functional and Biochemical Characterization of Hepatitis C Virus (HCV) Particles Produced in a Humanized Liver Mouse Model.
New Insights In Intestinal Sar1B GTPase Regulation and Role in Cholesterol Homeostasis.
Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression.
Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.
Cell culture-derived HCV cannot infect synovial fibroblasts.
Expression and regulation of scavenger receptor class B type 1 in the rat ovary and uterus during the estrous cycle.
A Western-fed diet increases plasma HDL and LDL-cholesterol levels in apoD-/- mice.
Hesperidin increases intestinal β,β-carotene 15-15' mono-oxygenase 1 (BCMO1) activity in Mongolian gerbils (Meriones unguiculatus) fed with β-carotene-free diet.
Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration.
Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins.
The orphan nuclear receptor Nr5a2 is essential for luteinization in the female mouse ovary.
Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.
Endoplasmic reticulum stress impairs cholesterol efflux and synthesis in hepatic cells.
Effect of combined mulberry leaf and fruit extract on liver and skin cholesterol transporters in high fat diet-induced obese mice.
Alternative endocytosis pathway for productive entry of hepatitis C virus.
HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms.
Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through upregulating ABCA1 and SR-BI within RCT.
Resveratrol protects SR-B1 levels in keratinocytes exposed to cigarette smoke.
Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development.
Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice.
ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders.
Knock-down of the oxysterol receptor LXRα impairs cholesterol efflux in human primary macrophages: lack of compensation by LXRβ activation.
Modulation of cholesterol transport by insulin-treated gestational diabetes mellitus in human full-term placenta.
Molecular mechanisms responsible for the reduced expression of cholesterol transporters from macrophages by low-dose endotoxin.
Resveratrol administration or SIRT1 overexpression does not increase LXR signaling and macrophage-to-feces reverse cholesterol transport in vivo.
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice.
Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry.
Effects of mixed micellar lipids on carotenoid uptake by human intestinal Caco-2 cells.
Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3.
Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice.
Cigarette smoke affects keratinocytes SRB1 expression and localization via H2O2 production and HNE protein adducts formation.
Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.
Host HDL biogenesis machinery is recruited to the inclusion of Chlamydia trachomatis-infected cells and regulates chlamydial growth.
ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading.
Regulation of the expression of key genes involved in HDL metabolism by unsaturated fatty acids.
Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus.
Respective contributions of intestinal Niemann-Pick C1-like 1 and scavenger receptor class B type I to cholesterol and tocopherol uptake: in vivo v. in vitro studies.
Ezetimibe ameliorates intestinal chylomicron overproduction and improves glucose tolerance in a diet-induced hamster model of insulin resistance.
Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI.
Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle.
Pharmacological LXR activation reduces presence of SR-B1 in liver membranes contributing to LXR-mediated induction of HDL-cholesterol.
Suppressed hepcidin expression correlates with hypotransferrinemia in copper-deficient rat pups but not dams.
High-fat and fructose intake induces insulin resistance, dyslipidemia, and liver steatosis and alters in vivo macrophage-to-feces reverse cholesterol transport in hamsters.
Intracellular cholesterol-binding proteins enhance HDL-mediated cholesterol uptake in cultured primary mouse hepatocytes.
The effect of 17{beta}-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu.
Nephrotic syndrome causes upregulation of HDL endocytic receptor and PDZK-1-dependent downregulation of HDL docking receptor.
Induction of macrophage scavenger receptor type BI expression by tamoxifen and 4-hydroxytamoxifen.
13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages.
Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes.
Differential stimulation pathways of progesterone secretion from newly formed corpora lutea in rats treated with ethylene glycol monomethyl ether, sulpiride, or atrazine.
Scavenger receptor SR-BI in macrophage lipid metabolism.
Autoimmune-mediated reduction of high-density lipoprotein-cholesterol and paraoxonase 1 activity in systemic lupus erythematosus-prone gld mice.
Cross-presentation of epitopes on virus-like particles via the MHC I receptor recycling pathway.
The structural basis for membrane binding and pore formation by lymphocyte perforin.
Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo.
Mouse-specific residues of claudin-1 limit hepatitis C virus genotype 2a infection in a human hepatocyte cell line.
The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice.
High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx.
Anemic copper-deficient rats, but not mice, display low hepcidin expression and high ferroportin levels.
Sensing of dietary lipids by enterocytes: a new role for SR-BI/CLA-1.
Pharmacological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis.
Mammalian Wnt3a is released on lipoprotein particles.
Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.
Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster.
Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney.
Overexpression of sterol carrier protein-2 differentially alters hepatic cholesterol accumulation in cholesterol-fed mice.
Macrophage sphingomyelin synthase 2 deficiency decreases atherosclerosis in mice.
LDLs stimulate p38 MAPKs and wound healing through SR-BI independently of Ras and PI3 kinase.
Expression of scavenger receptor-BI and low-density lipoprotein receptor and differential use of lipoproteins to support early steroidogenesis in luteinizing macaque granulosa cells.
CFTR knockdown stimulates lipid synthesis and transport in intestinal Caco-2/15 cells.
A single point mutation in E2 enhances hepatitis C virus infectivity and alters lipoprotein association of viral particles.
The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model.
The tight junction-associated protein occludin is required for a postbinding step in hepatitis C virus entry and infection.
Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages.
Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis.
CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages.
Liver fatty acid-binding protein gene-ablated female mice exhibit increased age-dependent obesity.
IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.
IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.
Intestinal fatty acid binding protein regulates mitochondrion beta-oxidation and cholesterol uptake.
CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice.
Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion.
Hormonal regulation of testicular steroid and cholesterol homeostasis.
Regulation of direct transintestinal cholesterol excretion in mice.
Role of caveolin-1 in the regulation of lipoprotein metabolism.
Coexpression of CLA-1 and human PDZK1 in murine liver modulates HDL cholesterol metabolism.
Reduced plasma high-density lipoprotein cholesterol in hyperthyroid mice coincides with decreased hepatic adenosine 5'-triphosphate-binding cassette transporter 1 expression.
SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL.
Oxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BI.
CD36 is one of important receptors promoting renal tubular injury by advanced oxidation protein products.
Ritonavir increases CD36, ABCA1 and CYP27 expression in THP-1 macrophages.
Discontinuous movement of mRNP particles in nucleoplasmic regions devoid of chromatin.
Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors.
Xanthophylls are preferentially taken up compared with beta-carotene by retinal cells via a SRBI-dependent mechanism.
Failure of adrenal corticosterone production in POMC-deficient mice results from lack of integrated effects of POMC peptides on multiple factors.
Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells.
Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters.
Mechanisms of provitamin A (carotenoid) and vitamin A (retinol) transport into and out of intestinal Caco-2 cells.
SCP-2/SCP-x gene ablation alters lipid raft domains in primary cultured mouse hepatocytes.
Paraoxonase 1 response to a high-fat diet: gender differences in the factors involved.
Effects of apoA-V on HDL and VLDL metabolism in APOC3 transgenic mice.
E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.
SR-BI undergoes cholesterol-stimulated transcytosis to the bile canaliculus in polarized WIF-B cells.
Intrauterine growth restriction is associated with alterations in placental lipoprotein receptors and maternal lipoprotein composition.
Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81.
NO-1886 upregulates ATP binding cassette transporter A1 and inhibits diet-induced atherosclerosis in Chinese Bama minipigs.
The age-related paraoxonase 1 response is altered by long-term caloric restriction in male and female rats.
The predominance of one of the SR-BI isoforms is associated with increased esterified cholesterol levels not apoptosis in mink testis.
Localization and role of NPC1L1 in cholesterol absorption in human intestine.
Hepatitis C virus E2 links soluble human CD81 and SR-B1 protein.
Persistent hepatitis C virus infection in vitro: coevolution of virus and host.
LDL and cAMP cooperate to regulate the functional expression of the LRP in rat ovarian granulosa cells.
Hepatic SR-BI-mediated cholesteryl ester selective uptake occurs with unaltered efficiency in the absence of cellular energy.
Localization of oxidized phosphatidylcholine in nonalcoholic fatty liver disease: impact on disease progression.
Effects of hepatic expression of the high-density lipoprotein receptor SR-BI on lipoprotein metabolism and female fertility.
Insulin and angiotensin II induce the translocation of scavenger receptor class B, type I from intracellular sites to the plasma membrane of adipocytes.
Scavenger receptor class B type I and hepatitis C virus infection of primary tupaia hepatocytes.
Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells.
Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors.
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.
Physiological importance of SR-BI in the in vivo metabolism of human HDL and LDL in male and female mice.
Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104).
Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol.
Acute tubular injury causes dysregulation of cellular cholesterol transport proteins.
Sepsis syndrome stimulates proximal tubule cholesterol synthesis and suppresses the SR-B1 cholesterol transporter.
Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression.
Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins.
Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins.
Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade.
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.
Effects of lipoprotein lipase on uptake and transcytosis of low density lipoprotein (LDL) and LDL-associated alpha-tocopherol in a porcine in vitro blood-brain barrier model.
p21-activated kinase-1 (PAK1) inhibition of the human scavenger receptor class B, type I promoter in macrophages is independent of PAK1 kinase activity, but requires the GTPase-binding domain.
Regulation by vitamin E of the scavenger receptor BI in rat liver and HepG2 cells.
Marshall JD, Courage ER, Elliott RF, Fitzpatrick MN, Kim AD, Lopez-Clavijo AF, Woolfrey BA, Ouimet M, Wakelam MJO, Brown RJ
PloS one 2020;15(5):e0233180
PloS one 2020;15(5):e0233180
Serum amyloid A is not incorporated into HDL during HDL biogenesis.
Ji A, Wang X, Noffsinger VP, Jennings D, de Beer MC, de Beer FC, Tannock LR, Webb NR
Journal of lipid research 2020 Mar;61(3):328-337
Journal of lipid research 2020 Mar;61(3):328-337
Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis.
Mutoh T, Shirai T, Ishii T, Shirota Y, Fujishima F, Takahashi F, Kakuta Y, Kanazawa Y, Masamune A, Saiki Y, Harigae H, Fujii H
Nature communications 2020 Mar 9;11(1):1253
Nature communications 2020 Mar 9;11(1):1253
Soraphen A enhances macrophage cholesterol efflux via indirect LXR activation and ABCA1 upregulation.
Wang D, Hiebl V, Schachner D, Ladurner A, Heiss EH, Atanasov AG, Dirsch VM
Biochemical pharmacology 2020 Jul;177:114022
Biochemical pharmacology 2020 Jul;177:114022
Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice.
Roscam Abbing RLP, Slijepcevic D, Donkers JM, Havinga R, Duijst S, Paulusma CC, Kuiper J, Kuipers F, Groen AK, Oude Elferink RPJ, van de Graaf SFJ
Hepatology (Baltimore, Md.) 2020 Jan;71(1):247-258
Hepatology (Baltimore, Md.) 2020 Jan;71(1):247-258
MicroRNA-205-5p Promotes Unstable Atherosclerotic Plaque Formation In Vivo.
Meng X, Yin J, Yu X, Guo Y
Cardiovascular drugs and therapy 2020 Feb;34(1):25-39
Cardiovascular drugs and therapy 2020 Feb;34(1):25-39
SR-BI Interactome Analysis Reveals a Proviral Role for UGGT1 in Hepatitis C Virus Entry.
Huang J, Yin H, Yin P, Jian X, Song S, Luan J, Zhang L
Frontiers in microbiology 2019;10:2043
Frontiers in microbiology 2019;10:2043
High soluble endoglin levels regulate cholesterol homeostasis and bile acids turnover in the liver of transgenic mice.
Dolezelova E, Sa ICI, Prasnicka A, Hroch M, Hyspler R, Ticha A, Lastuvkova H, Cermanova J, Pericacho M, Visek J, Lasticova M, Micuda S, Nachtigal P
Life sciences 2019 Sep 1;232:116643
Life sciences 2019 Sep 1;232:116643
Phagocytosis mediated by scavenger receptor class BI promotes macrophage transition during skeletal muscle regeneration.
Zhang J, Qu C, Li T, Cui W, Wang X, Du J
The Journal of biological chemistry 2019 Oct 25;294(43):15672-15685
The Journal of biological chemistry 2019 Oct 25;294(43):15672-15685
SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis.
Huang L, Chambliss KL, Gao X, Yuhanna IS, Behling-Kelly E, Bergaya S, Ahmed M, Michaely P, Luby-Phelps K, Darehshouri A, Xu L, Fisher EA, Ge WP, Mineo C, Shaul PW
Nature 2019 May;569(7757):565-569
Nature 2019 May;569(7757):565-569
Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I.
Wu ZY, Li H, Li JR, Lv XQ, Jiang JD, Peng ZG
European journal of pharmacology 2019 Jun 15;853:111-120
European journal of pharmacology 2019 Jun 15;853:111-120
Upregulation of Scavenger Receptor B1 Is Required for Steroidogenic and Nonsteroidogenic Cholesterol Metabolism in Prostate Cancer.
Gordon JA, Noble JW, Midha A, Derakhshan F, Wang G, Adomat HH, Tomlinson Guns ES, Lin YY, Ren S, Collins CC, Nelson PS, Morrissey C, Wasan KM, Cox ME
Cancer research 2019 Jul 1;79(13):3320-3331
Cancer research 2019 Jul 1;79(13):3320-3331
Prenatal exposure to valproate induces sex-, age-, and tissue-dependent alterations of cholesterol metabolism: Potential implications on autism.
Cartocci V, Tonini C, Di Pippo T, Vuono F, Schiavi S, Marino M, Trezza V, Pallottini V
Journal of cellular physiology 2019 Apr;234(4):4362-4374
Journal of cellular physiology 2019 Apr;234(4):4362-4374
Endoplasmic Reticulum Stress Affects Lipid Metabolism in Atherosclerosis Via CHOP Activation and Over-Expression of miR-33.
Sun Y, Zhang D, Liu X, Li X, Liu F, Yu Y, Jia S, Zhou Y, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(5):1995-2010
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(5):1995-2010
A role for scavenger receptor B1 as a captor of specific fatty acids in taste buds of circumvallate papillae.
Tsuzuki S, Lee S, Kimoto Y, Sugawara T, Manabe Y, Inoue K
Biomedical research (Tokyo, Japan) 2018;39(6):295-300
Biomedical research (Tokyo, Japan) 2018;39(6):295-300
A novel role for scavenger receptor B1 as a contributor to the capture of specific volatile odorants in the nasal cavity.
Tsuzuki S, Kimoto Y, Lee S, Sugawara T, Manabe Y, Inoue K
Biomedical research (Tokyo, Japan) 2018;39(3):117-129
Biomedical research (Tokyo, Japan) 2018;39(3):117-129
Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet.
Cairns R, Fischer AW, Blanco-Munoz P, Alvarez-Guaita A, Meneses-Salas E, Egert A, Buechler C, Hoy AJ, Heeren J, Enrich C, Rentero C, Grewal T
PloS one 2018;13(8):e0201310
PloS one 2018;13(8):e0201310
Apolipoprotein B-100 peptide 210 antibody inhibits atherosclerosis by regulation of macrophages that phagocytize oxidized lipid.
Zeng Z, Cao B, Guo X, Li W, Li S, Chen J, Zhou W, Zheng C, Wei Y
American journal of translational research 2018;10(6):1817-1828
American journal of translational research 2018;10(6):1817-1828
Experimental challenges regarding the in vitro investigation of the nanoparticle-biocorona in disease states.
Adamson SX, Lin Z, Chen R, Kobos L, Shannahan J
Toxicology in vitro : an international journal published in association with BIBRA 2018 Sep;51:40-49
Toxicology in vitro : an international journal published in association with BIBRA 2018 Sep;51:40-49
SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo.
Nishino T, Horie T, Baba O, Sowa N, Hanada R, Kuwabara Y, Nakao T, Nishiga M, Nishi H, Nakashima Y, Nakazeki F, Ide Y, Koyama S, Kimura M, Nagata M, Yoshida K, Takagi Y, Nakamura T, Hasegawa K, Miyamoto S, Kimura T, Ono K
Arteriosclerosis, thrombosis, and vascular biology 2018 Oct;38(10):2460-2473
Arteriosclerosis, thrombosis, and vascular biology 2018 Oct;38(10):2460-2473
Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells.
Sticozzi C, Pecorelli A, Romani A, Belmonte G, Cervellati F, Maioli E, Lila MA, Cervellati C, Valacchi G
Free radical biology & medicine 2018 Oct;126:287-295
Free radical biology & medicine 2018 Oct;126:287-295
Ablating both Fabp1 and Scp2/Scpx (TKO) induces hepatic phospholipid and cholesterol accumulation in high fat-fed mice.
Milligan S, Martin GG, Landrock D, McIntosh AL, Mackie JT, Schroeder F, Kier AB
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 Mar;1863(3):323-338
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 Mar;1863(3):323-338
Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell-derived hepatocytes.
Schöbel A, Rösch K, Herker E
Scientific reports 2018 Mar 1;8(1):3893
Scientific reports 2018 Mar 1;8(1):3893
Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs "in vitro" wound closure.
Muresan XM, Sticozzi C, Belmonte G, Savelli V, Evelson P, Valacchi G
Mechanisms of ageing and development 2018 Jun;172:78-85
Mechanisms of ageing and development 2018 Jun;172:78-85
Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells.
Gao F, Li G, Liu C, Gao H, Wang H, Liu W, Chen M, Shang Y, Wang L, Shi J, Xia W, Jiao J, Gao F, Li J, Chen L, Li W
The Journal of cell biology 2018 Jun 4;217(6):2103-2119
The Journal of cell biology 2018 Jun 4;217(6):2103-2119
6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages.
Wang D, Hiebl V, Ladurner A, Latkolik SL, Bucar F, Heiß EH, Dirsch VM, Atanasov AG
Molecular nutrition & food research 2018 Jul;62(14):e1800011
Molecular nutrition & food research 2018 Jul;62(14):e1800011
Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB.
Bruening J, Lasswitz L, Banse P, Kahl S, Marinach C, Vondran FW, Kaderali L, Silvie O, Pietschmann T, Meissner F, Gerold G
PLoS pathogens 2018 Jul;14(7):e1007111
PLoS pathogens 2018 Jul;14(7):e1007111
Novel interactomics approach identifies ABCA1 as direct target of evodiamine, which increases macrophage cholesterol efflux.
Wang L, Eftekhari P, Schachner D, Ignatova ID, Palme V, Schilcher N, Ladurner A, Heiss EH, Stangl H, Dirsch VM, Atanasov AG
Scientific reports 2018 Jul 23;8(1):11061
Scientific reports 2018 Jul 23;8(1):11061
A novel immortalized hepatocyte-like cell line (imHC) supports in vitro liver stage development of the human malarial parasite Plasmodium vivax.
Pewkliang Y, Rungin S, Lerdpanyangam K, Duangmanee A, Kanjanasirirat P, Suthivanich P, Sa-Ngiamsuntorn K, Borwornpinyo S, Sattabongkot J, Patrapuvich R, Hongeng S
Malaria journal 2018 Jan 25;17(1):50
Malaria journal 2018 Jan 25;17(1):50
HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner.
Durham KK, Chathely KM, Mak KC, Momen A, Thomas CT, Zhao YY, MacDonald ME, Curtis JM, Husain M, Trigatti BL
American journal of physiology. Heart and circulatory physiology 2018 Jan 1;314(1):H31-H44
American journal of physiology. Heart and circulatory physiology 2018 Jan 1;314(1):H31-H44
Cholesterol metabolism and Cx43, Cx46, and Cx50 gap junction protein expression and localization in normal and diabetic and obese ob/ob and db/db mouse testes.
Pelletier RM, Akpovi CD, Chen L, Vitale ML
American journal of physiology. Endocrinology and metabolism 2018 Jan 1;314(1):E21-E38
American journal of physiology. Endocrinology and metabolism 2018 Jan 1;314(1):E21-E38
Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding.
Zhu L, Shi J, Luu TN, Neuman JC, Trefts E, Yu S, Palmisano BT, Wasserman DH, Linton MF, Stafford JM
Molecular metabolism 2018 Feb;8:106-116
Molecular metabolism 2018 Feb;8:106-116
Altered Brain Cholesterol/Isoprenoid Metabolism in a Rat Model of Autism Spectrum Disorders.
Cartocci V, Catallo M, Tempestilli M, Segatto M, Pfrieger FW, Bronzuoli MR, Scuderi C, Servadio M, Trezza V, Pallottini V
Neuroscience 2018 Feb 21;372:27-37
Neuroscience 2018 Feb 21;372:27-37
High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2.
Durham KK, Chathely KM, Trigatti BL
The Biochemical journal 2018 Apr 5;475(7):1253-1265
The Biochemical journal 2018 Apr 5;475(7):1253-1265
FoxO transcription factors are required for hepatic HDL cholesterol clearance.
Lee SX, Heine M, Schlein C, Ramakrishnan R, Liu J, Belnavis G, Haimi I, Fischer AW, Ginsberg HN, Heeren J, Rinninger F, Haeusler RA
The Journal of clinical investigation 2018 Apr 2;128(4):1615-1626
The Journal of clinical investigation 2018 Apr 2;128(4):1615-1626
SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1.
Fung KY, Wang C, Nyegaard S, Heit B, Fairn GD, Lee WL
Frontiers in physiology 2017;8:841
Frontiers in physiology 2017;8:841
HCV replication in gastrointestinal mucosa: Potential extra-hepatic viral reservoir and possible role in HCV infection recurrence after liver transplantation.
Russelli G, Pizzillo P, Iannolo G, Barbera F, Tuzzolino F, Liotta R, Traina M, Vizzini G, Gridelli B, Badami E, Conaldi PG
PloS one 2017;12(7):e0181683
PloS one 2017;12(7):e0181683
Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages.
Qian Y, Qiao S, Dai Y, Xu G, Dai B, Lu L, Yu X, Luo Q, Zhang Z
ACS nano 2017 Sep 26;11(9):9536-9549
ACS nano 2017 Sep 26;11(9):9536-9549
Rational Targeting of Cellular Cholesterol in Diffuse Large B-Cell Lymphoma (DLBCL) Enabled by Functional Lipoprotein Nanoparticles: A Therapeutic Strategy Dependent on Cell of Origin.
Rink JS, Yang S, Cen O, Taxter T, McMahon KM, Misener S, Behdad A, Longnecker R, Gordon LI, Thaxton CS
Molecular pharmaceutics 2017 Nov 6;14(11):4042-4051
Molecular pharmaceutics 2017 Nov 6;14(11):4042-4051
LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis.
Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, Parks JS, Hammer RE, Boucher P, Tsai S, Herz J
eLife 2017 Nov 16;6
eLife 2017 Nov 16;6
Impact of dietary phytol on lipid metabolism in SCP2/SCPX/L-FABP null mice.
Milligan S, Martin GG, Landrock D, McIntosh AL, Mackie JT, Schroeder F, Kier AB
Biochimica et biophysica acta. Molecular and cell biology of lipids 2017 Mar;1862(3):291-304
Biochimica et biophysica acta. Molecular and cell biology of lipids 2017 Mar;1862(3):291-304
The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells.
Castella B, Kopecka J, Sciancalepore P, Mandili G, Foglietta M, Mitro N, Caruso D, Novelli F, Riganti C, Massaia M
Nature communications 2017 Jun 5;8:15663
Nature communications 2017 Jun 5;8:15663
Deconstructing Olfactory Stem Cell Trajectories at Single-Cell Resolution.
Fletcher RB, Das D, Gadye L, Street KN, Baudhuin A, Wagner A, Cole MB, Flores Q, Choi YG, Yosef N, Purdom E, Dudoit S, Risso D, Ngai J
Cell stem cell 2017 Jun 1;20(6):817-830.e8
Cell stem cell 2017 Jun 1;20(6):817-830.e8
Activation of liver X receptor suppresses angiogenesis via induction of ApoD.
Lai CJ, Cheng HC, Lin CY, Huang SH, Chen TH, Chung CJ, Chang CH, Wang HD, Chuu CP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5568-5576
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5568-5576
Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages.
Wang L, Palme V, Rotter S, Schilcher N, Cukaj M, Wang D, Ladurner A, Heiss EH, Stangl H, Dirsch VM, Atanasov AG
Molecular nutrition & food research 2017 Apr;61(4)
Molecular nutrition & food research 2017 Apr;61(4)
Apolipoprotein A-II Plus Lipid Emulsion Enhance Cell Growth via SR-B1 and Target Pancreatic Cancer In Vitro and In Vivo.
Julovi SM, Xue A, Thanh LE TN, Gill AJ, Bulanadi JC, Patel M, Waddington LJ, Rye KA, Moghaddam MJ, Smith RC
PloS one 2016;11(3):e0151475
PloS one 2016;11(3):e0151475
A New Signaling Pathway for HCV Inhibition by Estrogen: GPR30 Activation Leads to Cleavage of Occludin by MMP-9.
Ulitzky L, Lafer MM, KuKuruga MA, Silberstein E, Cehan N, Taylor DR
PloS one 2016;11(1):e0145212
PloS one 2016;11(1):e0145212
Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice.
Scharinger B, Messner B, Türkcan A, Schuster D, Vuorinen A, Pitterl F, Heinz K, Arnhard K, Laufer G, Grimm M, Stuppner H, Oberacher H, Eller P, Ritsch A, Bernhard D
Journal of molecular and cellular cardiology 2016 Oct;99:35-46
Journal of molecular and cellular cardiology 2016 Oct;99:35-46
A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection.
Jean Beltran PM, Mathias RA, Cristea IM
Cell systems 2016 Oct 26;3(4):361-373.e6
Cell systems 2016 Oct 26;3(4):361-373.e6
The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis.
Geng S, Chen K, Yuan R, Peng L, Maitra U, Diao N, Chen C, Zhang Y, Hu Y, Qi CF, Pierce S, Ling W, Xiong H, Li L
Nature communications 2016 Nov 8;7:13436
Nature communications 2016 Nov 8;7:13436
ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer.
Cedó L, García-León A, Baila-Rueda L, Santos D, Grijalva V, Martínez-Cignoni MR, Carbó JM, Metso J, López-Vilaró L, Zorzano A, Valledor AF, Cenarro A, Jauhiainen M, Lerma E, Fogelman AM, Reddy ST, Escolà-Gil JC, Blanco-Vaca F
Scientific reports 2016 Nov 3;6:36387
Scientific reports 2016 Nov 3;6:36387
Up-regulated expression of scavenger receptor class B type 1 (SR-B1) is associated with malignant behaviors and poor prognosis of breast cancer.
Li J, Wang J, Li M, Yin L, Li XA, Zhang TG
Pathology, research and practice 2016 Jun;212(6):555-9
Pathology, research and practice 2016 Jun;212(6):555-9
High-density lipoprotein inhibits ox-LDL-induced adipokine secretion by upregulating SR-BI expression and suppressing ER Stress pathway.
Song G, Wu X, Zhang P, Yu Y, Yang M, Jiao P, Wang N, Song H, Wu Y, Zhang X, Liu H, Qin S
Scientific reports 2016 Jul 29;6:30889
Scientific reports 2016 Jul 29;6:30889
Lanatoside C Promotes Foam Cell Formation and Atherosclerosis.
Shi H, Mao X, Zhong Y, Liu Y, Zhao X, Yu K, Zhu R, Wei Y, Zhu J, Sun H, Mao Y, Zeng Q
Scientific reports 2016 Jan 29;6:20154
Scientific reports 2016 Jan 29;6:20154
Difference in expression patterns of placental cholesterol transporters, ABCA1 and SR-BI, in Meishan and Yorkshire pigs with different placental efficiency.
Hong L, Xu X, Huang J, Lei M, Xu D, Zhao S, Yu M
Scientific reports 2016 Feb 8;6:20503
Scientific reports 2016 Feb 8;6:20503
CD36 is a co-receptor for hepatitis C virus E1 protein attachment.
Cheng JJ, Li JR, Huang MH, Ma LL, Wu ZY, Jiang CC, Li WJ, Li YH, Han YX, Li H, Chen JH, Wang YX, Song DQ, Peng ZG, Jiang JD
Scientific reports 2016 Feb 22;6:21808
Scientific reports 2016 Feb 22;6:21808
Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells.
Ganesan LP, Mates JM, Cheplowitz AM, Avila CL, Zimmerer JM, Yao Z, Maiseyeu A, Rajaram MV, Robinson JM, Anderson CL
Scientific reports 2016 Feb 11;6:20646
Scientific reports 2016 Feb 11;6:20646
MicroRNA-192* impairs adipocyte triglyceride storage.
Mysore R, Zhou Y, Sädevirta S, Savolainen-Peltonen H, Nidhina Haridas PA, Soronen J, Leivonen M, Sarin AP, Fischer-Posovszky P, Wabitsch M, Yki-Järvinen H, Olkkonen VM
Biochimica et biophysica acta 2016 Apr;1861(4):342-51
Biochimica et biophysica acta 2016 Apr;1861(4):342-51
Impact of Silver and Iron Nanoparticle Exposure on Cholesterol Uptake by Macrophages.
Shannahan JH, Sowrirajan H, Persaud I, Podila R, Brown JM
Journal of nanomaterials 2015;2015
Journal of nanomaterials 2015;2015
A Novel Anti-Inflammatory Effect for High Density Lipoprotein.
Cameron SJ, Morrell CN, Bao C, Swaim AF, Rodriguez A, Lowenstein CJ
PloS one 2015;10(12):e0144372
PloS one 2015;10(12):e0144372
Coenzyme Q10 consumption promotes ABCG1-mediated macrophage cholesterol efflux: a randomized, double-blind, placebo-controlled, cross-over study in healthy volunteers.
Yan X, Shen T, Jiang X, Tang X, Wang D, Li H, Ling W
Molecular nutrition & food research 2015 Sep;59(9):1725-34
Molecular nutrition & food research 2015 Sep;59(9):1725-34
Functional and Biochemical Characterization of Hepatitis C Virus (HCV) Particles Produced in a Humanized Liver Mouse Model.
Calattini S, Fusil F, Mancip J, Dao Thi VL, Granier C, Gadot N, Scoazec JY, Zeisel MB, Baumert TF, Lavillette D, Dreux M, Cosset FL
The Journal of biological chemistry 2015 Sep 18;290(38):23173-87
The Journal of biological chemistry 2015 Sep 18;290(38):23173-87
New Insights In Intestinal Sar1B GTPase Regulation and Role in Cholesterol Homeostasis.
Sané A, Seidman E, Spahis S, Lamantia V, Garofalo C, Montoudis A, Marcil V, Levy E
Journal of cellular biochemistry 2015 Oct;116(10):2270-82
Journal of cellular biochemistry 2015 Oct;116(10):2270-82
Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression.
Bartels ED, Christoffersen C, Lindholm MW, Nielsen LB
Circulation research 2015 Nov 6;117(11):933-42
Circulation research 2015 Nov 6;117(11):933-42
Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.
Ng S, Schwartz RE, March S, Galstian A, Gural N, Shan J, Prabhu M, Mota MM, Bhatia SN
Stem cell reports 2015 Mar 10;4(3):348-59
Stem cell reports 2015 Mar 10;4(3):348-59
Cell culture-derived HCV cannot infect synovial fibroblasts.
Nadeem AE, Thomas P, Ulf ML, Elena N, Anggakusuma A, Mohamed BM, Frank P, Patrick B
Scientific reports 2015 Dec 8;5:18043
Scientific reports 2015 Dec 8;5:18043
Expression and regulation of scavenger receptor class B type 1 in the rat ovary and uterus during the estrous cycle.
Wang Y, Meng C, Wei Q, Shi F, Mao D
Acta histochemica 2015 Apr;117(3):297-304
Acta histochemica 2015 Apr;117(3):297-304
A Western-fed diet increases plasma HDL and LDL-cholesterol levels in apoD-/- mice.
Ali K, Abo-Ali EM, Kabir MD, Riggins B, Nguy S, Li L, Srivastava U, Thinn SM
PloS one 2014;9(12):e115744
PloS one 2014;9(12):e115744
Hesperidin increases intestinal β,β-carotene 15-15' mono-oxygenase 1 (BCMO1) activity in Mongolian gerbils (Meriones unguiculatus) fed with β-carotene-free diet.
Poulaert M, Gunata Z, During A, Reboul E, Laurent C, Gaillet S, Dhuique-Mayer C
Food chemistry 2014 Sep 15;159:477-85
Food chemistry 2014 Sep 15;159:477-85
Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration.
Ye R, Holland WL, Gordillo R, Wang M, Wang QA, Shao M, Morley TS, Gupta RK, Stahl A, Scherer PE
eLife 2014 Oct 23;3
eLife 2014 Oct 23;3
Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins.
Bankwitz D, Vieyres G, Hueging K, Bitzegeio J, Doepke M, Chhatwal P, Haid S, Catanese MT, Zeisel MB, Nicosia A, Baumert TF, Kaderali L, Pietschmann T
Journal of virology 2014 Nov;88(21):12644-55
Journal of virology 2014 Nov;88(21):12644-55
The orphan nuclear receptor Nr5a2 is essential for luteinization in the female mouse ovary.
Bertolin K, Gossen J, Schoonjans K, Murphy BD
Endocrinology 2014 May;155(5):1931-43
Endocrinology 2014 May;155(5):1931-43
Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cells.
Frentzen A, Anggakusuma, Gürlevik E, Hueging K, Knocke S, Ginkel C, Brown RJ, Heim M, Dill MT, Kröger A, Kalinke U, Kaderali L, Kuehnel F, Pietschmann T
Hepatology (Baltimore, Md.) 2014 Jan;59(1):78-88
Hepatology (Baltimore, Md.) 2014 Jan;59(1):78-88
Endoplasmic reticulum stress impairs cholesterol efflux and synthesis in hepatic cells.
Röhrl C, Eigner K, Winter K, Korbelius M, Obrowsky S, Kratky D, Kovacs WJ, Stangl H
Journal of lipid research 2014 Jan;55(1):94-103
Journal of lipid research 2014 Jan;55(1):94-103
Effect of combined mulberry leaf and fruit extract on liver and skin cholesterol transporters in high fat diet-induced obese mice.
Valacchi G, Belmonte G, Miracco C, Eo H, Lim Y
Nutrition research and practice 2014 Feb;8(1):20-6
Nutrition research and practice 2014 Feb;8(1):20-6
Alternative endocytosis pathway for productive entry of hepatitis C virus.
Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, Matsuura Y, Suzuki T, Wakita T
The Journal of general virology 2014 Dec;95(Pt 12):2658-2667
The Journal of general virology 2014 Dec;95(Pt 12):2658-2667
HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms.
Emert B, Hasin-Brumshtein Y, Springstead JR, Vakili L, Berliner JA, Lusis AJ
Journal of lipid research 2014 Aug;55(8):1678-92
Journal of lipid research 2014 Aug;55(8):1678-92
Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through upregulating ABCA1 and SR-BI within RCT.
Xu Y, Liu Q, Xu Y, Liu C, Wang X, He X, Zhu N, Liu J, Wu Y, Li Y, Li N, Feng T, Lai F, Zhang M, Hong B, Jiang JD, Si S
Journal of lipid research 2014 Aug;55(8):1634-47
Journal of lipid research 2014 Aug;55(8):1634-47
Resveratrol protects SR-B1 levels in keratinocytes exposed to cigarette smoke.
Sticozzi C, Belmonte G, Cervellati F, Muresan XM, Pessina F, Lim Y, Forman HJ, Valacchi G
Free radical biology & medicine 2014 Apr;69:50-7
Free radical biology & medicine 2014 Apr;69:50-7
Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development.
Danilo C, Gutierrez-Pajares JL, Mainieri MA, Mercier I, Lisanti MP, Frank PG
Breast cancer research : BCR 2013;15(5):R87
Breast cancer research : BCR 2013;15(5):R87
Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice.
Bura KS, Lord C, Marshall S, McDaniel A, Thomas G, Warrier M, Zhang J, Davis MA, Sawyer JK, Shah R, Wilson MD, Dikkers A, Tietge UJF, Collet X, Rudel LL, Temel RE, Brown JM
Journal of lipid research 2013 Jun;54(6):1567-1577
Journal of lipid research 2013 Jun;54(6):1567-1577
ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders.
Nam H, Wang CY, Zhang L, Zhang W, Hojyo S, Fukada T, Knutson MD
Haematologica 2013 Jul;98(7):1049-57
Haematologica 2013 Jul;98(7):1049-57
Knock-down of the oxysterol receptor LXRα impairs cholesterol efflux in human primary macrophages: lack of compensation by LXRβ activation.
Ishibashi M, Filomenko R, Rébé C, Chevriaux A, Varin A, Derangère V, Bessède G, Gambert P, Lagrost L, Masson D
Biochemical pharmacology 2013 Jul 1;86(1):122-9
Biochemical pharmacology 2013 Jul 1;86(1):122-9
Modulation of cholesterol transport by insulin-treated gestational diabetes mellitus in human full-term placenta.
Dubé E, Ethier-Chiasson M, Lafond J
Biology of reproduction 2013 Jan;88(1):16
Biology of reproduction 2013 Jan;88(1):16
Molecular mechanisms responsible for the reduced expression of cholesterol transporters from macrophages by low-dose endotoxin.
Maitra U, Li L
Arteriosclerosis, thrombosis, and vascular biology 2013 Jan;33(1):24-33
Arteriosclerosis, thrombosis, and vascular biology 2013 Jan;33(1):24-33
Resveratrol administration or SIRT1 overexpression does not increase LXR signaling and macrophage-to-feces reverse cholesterol transport in vivo.
Escolà-Gil JC, Julve J, Llaverias G, Urpi-Sarda M, Silvennoinen R, Lee-Rueckert M, Andres-Lacueva C, Blanco-Vaca F
Translational research : the journal of laboratory and clinical medicine 2013 Feb;161(2):110-7
Translational research : the journal of laboratory and clinical medicine 2013 Feb;161(2):110-7
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
Khan OM, Akula MK, Skålen K, Karlsson C, Ståhlman M, Young SG, Borén J, Bergo MO
Circulation 2013 Feb 19;127(7):782-90
Circulation 2013 Feb 19;127(7):782-90
The combination of L-4F and simvastatin stimulate cholesterol efflux and related proteins expressions to reduce atherosclerotic lesions in apoE knockout mice.
Ying R, Yuan Y, Qin YF, Tian D, Feng L, Guo ZG, Sun YX, Li MX
Lipids in health and disease 2013 Dec 8;12:180
Lipids in health and disease 2013 Dec 8;12:180
Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry.
Kim S, Ishida H, Yamane D, Yi M, Swinney DC, Foung S, Lemon SM
Journal of virology 2013 Apr;87(8):4214-24
Journal of virology 2013 Apr;87(8):4214-24
Effects of mixed micellar lipids on carotenoid uptake by human intestinal Caco-2 cells.
Kotake-Nara E, Nagao A
Bioscience, biotechnology, and biochemistry 2012;76(5):875-82
Bioscience, biotechnology, and biochemistry 2012;76(5):875-82
Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3.
Jarajapu YP, Cai J, Yan Y, Li Calzi S, Kielczewski JL, Hu P, Shaw LC, Firth SM, Chan-Ling T, Boulton ME, Baxter RC, Grant MB
PloS one 2012;7(7):e39398
PloS one 2012;7(7):e39398
Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice.
Lundåsen T, Andersson EM, Snaith M, Lindmark H, Lundberg J, Östlund-Lindqvist AM, Angelin B, Rudling M
PloS one 2012;7(5):e37787
PloS one 2012;7(5):e37787
Cigarette smoke affects keratinocytes SRB1 expression and localization via H2O2 production and HNE protein adducts formation.
Sticozzi C, Belmonte G, Pecorelli A, Arezzini B, Gardi C, Maioli E, Miracco C, Toscano M, Forman HJ, Valacchi G
PloS one 2012;7(3):e33592
PloS one 2012;7(3):e33592
Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.
Dao Thi VL, Granier C, Zeisel MB, Guérin M, Mancip J, Granio O, Penin F, Lavillette D, Bartenschlager R, Baumert TF, Cosset FL, Dreux M
The Journal of biological chemistry 2012 Sep 7;287(37):31242-57
The Journal of biological chemistry 2012 Sep 7;287(37):31242-57
Host HDL biogenesis machinery is recruited to the inclusion of Chlamydia trachomatis-infected cells and regulates chlamydial growth.
Cox JV, Naher N, Abdelrahman YM, Belland RJ
Cellular microbiology 2012 Oct;14(10):1497-512
Cellular microbiology 2012 Oct;14(10):1497-512
ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading.
Wang CY, Jenkitkasemwong S, Duarte S, Sparkman BK, Shawki A, Mackenzie B, Knutson MD
The Journal of biological chemistry 2012 Oct 5;287(41):34032-43
The Journal of biological chemistry 2012 Oct 5;287(41):34032-43
Regulation of the expression of key genes involved in HDL metabolism by unsaturated fatty acids.
Kuang YL, Paulson KE, Lichtenstein AH, Lamon-Fava S
The British journal of nutrition 2012 Oct 28;108(8):1351-9
The British journal of nutrition 2012 Oct 28;108(8):1351-9
Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus.
Koga T, Ichinose K, Mizui M, Crispín JC, Tsokos GC
Journal of immunology (Baltimore, Md. : 1950) 2012 Oct 1;189(7):3490-6
Journal of immunology (Baltimore, Md. : 1950) 2012 Oct 1;189(7):3490-6
Respective contributions of intestinal Niemann-Pick C1-like 1 and scavenger receptor class B type I to cholesterol and tocopherol uptake: in vivo v. in vitro studies.
Reboul E, Soayfane Z, Goncalves A, Cantiello M, Bott R, Nauze M, Tercé F, Collet X, Coméra C
The British journal of nutrition 2012 May;107(9):1296-304
The British journal of nutrition 2012 May;107(9):1296-304
Ezetimibe ameliorates intestinal chylomicron overproduction and improves glucose tolerance in a diet-induced hamster model of insulin resistance.
Naples M, Baker C, Lino M, Iqbal J, Hussain MM, Adeli K
American journal of physiology. Gastrointestinal and liver physiology 2012 May 1;302(9):G1043-52
American journal of physiology. Gastrointestinal and liver physiology 2012 May 1;302(9):G1043-52
Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI.
Ji A, Wroblewski JM, Cai L, de Beer MC, Webb NR, van der Westhuyzen DR
Journal of lipid research 2012 Mar;53(3):446-455
Journal of lipid research 2012 Mar;53(3):446-455
Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle.
Molina-Jimenez F, Benedicto I, Dao Thi VL, Gondar V, Lavillette D, Marin JJ, Briz O, Moreno-Otero R, Aldabe R, Baumert TF, Cosset FL, Lopez-Cabrera M, Majano PL
Virology 2012 Mar 30;425(1):31-9
Virology 2012 Mar 30;425(1):31-9
Pharmacological LXR activation reduces presence of SR-B1 in liver membranes contributing to LXR-mediated induction of HDL-cholesterol.
Grefhorst A, Oosterveer MH, Brufau G, Boesjes M, Kuipers F, Groen AK
Atherosclerosis 2012 Jun;222(2):382-9
Atherosclerosis 2012 Jun;222(2):382-9
Suppressed hepcidin expression correlates with hypotransferrinemia in copper-deficient rat pups but not dams.
Broderius M, Mostad E, Prohaska JR
Genes & nutrition 2012 Jul;7(3):405-14
Genes & nutrition 2012 Jul;7(3):405-14
High-fat and fructose intake induces insulin resistance, dyslipidemia, and liver steatosis and alters in vivo macrophage-to-feces reverse cholesterol transport in hamsters.
Briand F, Thiéblemont Q, Muzotte E, Sulpice T
The Journal of nutrition 2012 Apr;142(4):704-9
The Journal of nutrition 2012 Apr;142(4):704-9
Intracellular cholesterol-binding proteins enhance HDL-mediated cholesterol uptake in cultured primary mouse hepatocytes.
Storey SM, McIntosh AL, Huang H, Landrock KK, Martin GG, Landrock D, Payne HR, Atshaves BP, Kier AB, Schroeder F
American journal of physiology. Gastrointestinal and liver physiology 2012 Apr 15;302(8):G824-39
American journal of physiology. Gastrointestinal and liver physiology 2012 Apr 15;302(8):G824-39
The effect of 17{beta}-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu.
Corcoran MP, Lichtenstein AH, Meydani M, Dillard A, Schaefer EJ, Lamon-Fava S
Journal of molecular endocrinology 2011;47(1):109-17
Journal of molecular endocrinology 2011;47(1):109-17
Nephrotic syndrome causes upregulation of HDL endocytic receptor and PDZK-1-dependent downregulation of HDL docking receptor.
Vaziri ND, Gollapudi P, Han S, Farahmand G, Yuan J, Rahimi A, Moradi H
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011 Oct;26(10):3118-23
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011 Oct;26(10):3118-23
Induction of macrophage scavenger receptor type BI expression by tamoxifen and 4-hydroxytamoxifen.
Dong P, Xie T, Zhou X, Hu W, Chen Y, Duan Y, Li X, Han J
Atherosclerosis 2011 Oct;218(2):435-42
Atherosclerosis 2011 Oct;218(2):435-42
13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages.
Kämmerer I, Ringseis R, Biemann R, Wen G, Eder K
Lipids in health and disease 2011 Nov 30;10:222
Lipids in health and disease 2011 Nov 30;10:222
Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes.
Koller E, Vincent TM, Chappell A, De S, Manoharan M, Bennett CF
Nucleic acids research 2011 Jun;39(11):4795-807
Nucleic acids research 2011 Jun;39(11):4795-807
Differential stimulation pathways of progesterone secretion from newly formed corpora lutea in rats treated with ethylene glycol monomethyl ether, sulpiride, or atrazine.
Taketa Y, Yoshida M, Inoue K, Takahashi M, Sakamoto Y, Watanabe G, Taya K, Yamate J, Nishikawa A
Toxicological sciences : an official journal of the Society of Toxicology 2011 Jun;121(2):267-78
Toxicological sciences : an official journal of the Society of Toxicology 2011 Jun;121(2):267-78
Scavenger receptor SR-BI in macrophage lipid metabolism.
Ji A, Meyer JM, Cai L, Akinmusire A, de Beer MC, Webb NR, van der Westhuyzen DR
Atherosclerosis 2011 Jul;217(1):106-12
Atherosclerosis 2011 Jul;217(1):106-12
Autoimmune-mediated reduction of high-density lipoprotein-cholesterol and paraoxonase 1 activity in systemic lupus erythematosus-prone gld mice.
Srivastava R, Yu S, Parks BW, Black LL, Kabarowski JH
Arthritis and rheumatism 2011 Jan;63(1):201-11
Arthritis and rheumatism 2011 Jan;63(1):201-11
Cross-presentation of epitopes on virus-like particles via the MHC I receptor recycling pathway.
Win SJ, Ward VK, Dunbar PR, Young SL, Baird MA
Immunology and cell biology 2011 Aug;89(6):681-8
Immunology and cell biology 2011 Aug;89(6):681-8
The structural basis for membrane binding and pore formation by lymphocyte perforin.
Law RH, Lukoyanova N, Voskoboinik I, Caradoc-Davies TT, Baran K, Dunstone MA, D'Angelo ME, Orlova EV, Coulibaly F, Verschoor S, Browne KA, Ciccone A, Kuiper MJ, Bird PI, Trapani JA, Saibil HR, Whisstock JC
Nature 2010 Nov 18;468(7322):447-51
Nature 2010 Nov 18;468(7322):447-51
Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo.
Hoppmann S, Steinbach J, Pietzsch J
The international journal of biochemistry & cell biology 2010 May;42(5):651-61
The international journal of biochemistry & cell biology 2010 May;42(5):651-61
Mouse-specific residues of claudin-1 limit hepatitis C virus genotype 2a infection in a human hepatocyte cell line.
Haid S, Windisch MP, Bartenschlager R, Pietschmann T
Journal of virology 2010 Jan;84(2):964-75
Journal of virology 2010 Jan;84(2):964-75
The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice.
Tancevski I, Demetz E, Eller P, Duwensee K, Hoefer J, Heim C, Stanzl U, Wehinger A, Auer K, Karer R, Huber J, Schgoer W, Van Eck M, Vanhoutte J, Fievet C, Stellaard F, Rudling M, Patsch JR, Ritsch A
PloS one 2010 Jan 15;5(1):e8722
PloS one 2010 Jan 15;5(1):e8722
High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx.
Gantman A, Fuhrman B, Aviram M, Hayek T
Biochemical and biophysical research communications 2010 Jan 1;391(1):523-8
Biochemical and biophysical research communications 2010 Jan 1;391(1):523-8
Anemic copper-deficient rats, but not mice, display low hepcidin expression and high ferroportin levels.
Jenkitkasemwong S, Broderius M, Nam H, Prohaska JR, Knutson MD
The Journal of nutrition 2010 Apr;140(4):723-30
The Journal of nutrition 2010 Apr;140(4):723-30
Sensing of dietary lipids by enterocytes: a new role for SR-BI/CLA-1.
Béaslas O, Cueille C, Delers F, Chateau D, Chambaz J, Rousset M, Carrière V
PloS one 2009;4(1):e4278
PloS one 2009;4(1):e4278
Pharmacological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis.
Arakawa R, Tsujita M, Iwamoto N, Ito-Ohsumi C, Lu R, Wu CA, Shimizu K, Aotsuka T, Kanazawa H, Abe-Dohmae S, Yokoyama S
Journal of lipid research 2009 Nov;50(11):2299-305
Journal of lipid research 2009 Nov;50(11):2299-305
Mammalian Wnt3a is released on lipoprotein particles.
Neumann S, Coudreuse DY, van der Westhuyzen DR, Eckhardt ER, Korswagen HC, Schmitz G, Sprong H
Traffic (Copenhagen, Denmark) 2009 Mar;10(3):334-43
Traffic (Copenhagen, Denmark) 2009 Mar;10(3):334-43
Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.
Karasinska JM, Rinninger F, Lütjohann D, Ruddle P, Franciosi S, Kruit JK, Singaraja RR, Hirsch-Reinshagen V, Fan J, Brunham LR, Bissada N, Ramakrishnan R, Wellington CL, Parks JS, Hayden MR
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Mar 18;29(11):3579-89
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Mar 18;29(11):3579-89
Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster.
Burke KT, Colvin PL, Myatt L, Graf GA, Schroeder F, Woollett LA
Journal of lipid research 2009 Jun;50(6):1146-55
Journal of lipid research 2009 Jun;50(6):1146-55
Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney.
Kim HJ, Moradi H, Yuan J, Norris K, Vaziri ND
American journal of physiology. Renal physiology 2009 Jun;296(6):F1297-306
American journal of physiology. Renal physiology 2009 Jun;296(6):F1297-306
Overexpression of sterol carrier protein-2 differentially alters hepatic cholesterol accumulation in cholesterol-fed mice.
Atshaves BP, McIntosh AL, Martin GG, Landrock D, Payne HR, Bhuvanendran S, Landrock KK, Lyuksyutova OI, Johnson JD, Macfarlane RD, Kier AB, Schroeder F
Journal of lipid research 2009 Jul;50(7):1429-47
Journal of lipid research 2009 Jul;50(7):1429-47
Macrophage sphingomyelin synthase 2 deficiency decreases atherosclerosis in mice.
Liu J, Huan C, Chakraborty M, Zhang H, Lu D, Kuo MS, Cao G, Jiang XC
Circulation research 2009 Jul 31;105(3):295-303
Circulation research 2009 Jul 31;105(3):295-303
LDLs stimulate p38 MAPKs and wound healing through SR-BI independently of Ras and PI3 kinase.
Bulat N, Waeber G, Widmann C
Journal of lipid research 2009 Jan;50(1):81-9
Journal of lipid research 2009 Jan;50(1):81-9
Expression of scavenger receptor-BI and low-density lipoprotein receptor and differential use of lipoproteins to support early steroidogenesis in luteinizing macaque granulosa cells.
Cherian-Shaw M, Puttabyatappa M, Greason E, Rodriguez A, VandeVoort CA, Chaffin CL
Endocrinology 2009 Feb;150(2):957-65
Endocrinology 2009 Feb;150(2):957-65
CFTR knockdown stimulates lipid synthesis and transport in intestinal Caco-2/15 cells.
Mailhot G, Ravid Z, Barchi S, Moreau A, Rabasa-Lhoret R, Levy E
American journal of physiology. Gastrointestinal and liver physiology 2009 Dec;297(6):G1239-49
American journal of physiology. Gastrointestinal and liver physiology 2009 Dec;297(6):G1239-49
A single point mutation in E2 enhances hepatitis C virus infectivity and alters lipoprotein association of viral particles.
Tao W, Xu C, Ding Q, Li R, Xiang Y, Chung J, Zhong J
Virology 2009 Dec 5;395(1):67-76
Virology 2009 Dec 5;395(1):67-76
The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model.
Schäfer G, Guler R, Murray G, Brombacher F, Brown GD
PloS one 2009 Dec 24;4(12):e8448
PloS one 2009 Dec 24;4(12):e8448
The tight junction-associated protein occludin is required for a postbinding step in hepatitis C virus entry and infection.
Benedicto I, Molina-Jiménez F, Bartosch B, Cosset FL, Lavillette D, Prieto J, Moreno-Otero R, Valenzuela-Fernández A, Aldabe R, López-Cabrera M, Majano PL
Journal of virology 2009 Aug;83(16):8012-20
Journal of virology 2009 Aug;83(16):8012-20
Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages.
Hongo S, Watanabe T, Arita S, Kanome T, Kageyama H, Shioda S, Miyazaki A
American journal of physiology. Endocrinology and metabolism 2009 Aug;297(2):E474-82
American journal of physiology. Endocrinology and metabolism 2009 Aug;297(2):E474-82
Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis.
Xu G, Watanabe T, Iso Y, Koba S, Sakai T, Nagashima M, Arita S, Hongo S, Ota H, Kobayashi Y, Miyazaki A, Hirano T
Circulation research 2009 Aug 28;105(5):500-10
Circulation research 2009 Aug 28;105(5):500-10
CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages.
Bujold K, Rhainds D, Jossart C, Febbraio M, Marleau S, Ong H
Cardiovascular research 2009 Aug 1;83(3):457-64
Cardiovascular research 2009 Aug 1;83(3):457-64
Liver fatty acid-binding protein gene-ablated female mice exhibit increased age-dependent obesity.
Martin GG, Atshaves BP, McIntosh AL, Mackie JT, Kier AB, Schroeder F
The Journal of nutrition 2008 Oct;138(10):1859-65
The Journal of nutrition 2008 Oct;138(10):1859-65
IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.
Shimizu E, Kawahara K, Kajizono M, Sawada M, Nakayama H
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6503-13
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6503-13
IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.
Shimizu E, Kawahara K, Kajizono M, Sawada M, Nakayama H
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6503-13
Journal of immunology (Baltimore, Md. : 1950) 2008 Nov 1;181(9):6503-13
Intestinal fatty acid binding protein regulates mitochondrion beta-oxidation and cholesterol uptake.
Montoudis A, Seidman E, Boudreau F, Beaulieu JF, Menard D, Elchebly M, Mailhot G, Sane AT, Lambert M, Delvin E, Levy E
Journal of lipid research 2008 May;49(5):961-72
Journal of lipid research 2008 May;49(5):961-72
CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice.
Drover VA, Nguyen DV, Bastie CC, Darlington YF, Abumrad NA, Pessin JE, London E, Sahoo D, Phillips MC
The Journal of biological chemistry 2008 May 9;283(19):13108-15
The Journal of biological chemistry 2008 May 9;283(19):13108-15
Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion.
Tietge UJ, Nijstad N, Havinga R, Baller JF, van der Sluijs FH, Bloks VW, Gautier T, Kuipers F
Journal of lipid research 2008 Mar;49(3):563-71
Journal of lipid research 2008 Mar;49(3):563-71
Hormonal regulation of testicular steroid and cholesterol homeostasis.
Eacker SM, Agrawal N, Qian K, Dichek HL, Gong EY, Lee K, Braun RE
Molecular endocrinology (Baltimore, Md.) 2008 Mar;22(3):623-35
Molecular endocrinology (Baltimore, Md.) 2008 Mar;22(3):623-35
Regulation of direct transintestinal cholesterol excretion in mice.
van der Velde AE, Vrins CL, van den Oever K, Seemann I, Oude Elferink RP, van Eck M, Kuipers F, Groen AK
American journal of physiology. Gastrointestinal and liver physiology 2008 Jul;295(1):G203-G208
American journal of physiology. Gastrointestinal and liver physiology 2008 Jul;295(1):G203-G208
Role of caveolin-1 in the regulation of lipoprotein metabolism.
Frank PG, Pavlides S, Cheung MW, Daumer K, Lisanti MP
American journal of physiology. Cell physiology 2008 Jul;295(1):C242-8
American journal of physiology. Cell physiology 2008 Jul;295(1):C242-8
Coexpression of CLA-1 and human PDZK1 in murine liver modulates HDL cholesterol metabolism.
Komori H, Arai H, Kashima T, Huby T, Kita T, Ueda Y
Arteriosclerosis, thrombosis, and vascular biology 2008 Jul;28(7):1298-303
Arteriosclerosis, thrombosis, and vascular biology 2008 Jul;28(7):1298-303
Reduced plasma high-density lipoprotein cholesterol in hyperthyroid mice coincides with decreased hepatic adenosine 5'-triphosphate-binding cassette transporter 1 expression.
Tancevski I, Wehinger A, Demetz E, Eller P, Duwensee K, Huber J, Hochegger K, Schgoer W, Fievet C, Stellaard F, Rudling M, Patsch JR, Ritsch A
Endocrinology 2008 Jul;149(7):3708-12
Endocrinology 2008 Jul;149(7):3708-12
SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL.
Yvan-Charvet L, Pagler TA, Wang N, Senokuchi T, Brundert M, Li H, Rinninger F, Tall AR
Journal of lipid research 2008 Jan;49(1):107-14
Journal of lipid research 2008 Jan;49(1):107-14
Oxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BI.
Valiyaveettil M, Kar N, Ashraf MZ, Byzova TV, Febbraio M, Podrez EA
Blood 2008 Feb 15;111(4):1962-71
Blood 2008 Feb 15;111(4):1962-71
CD36 is one of important receptors promoting renal tubular injury by advanced oxidation protein products.
Iwao Y, Nakajou K, Nagai R, Kitamura K, Anraku M, Maruyama T, Otagiri M
American journal of physiology. Renal physiology 2008 Dec;295(6):F1871-80
American journal of physiology. Renal physiology 2008 Dec;295(6):F1871-80
Ritonavir increases CD36, ABCA1 and CYP27 expression in THP-1 macrophages.
Pou J, Rebollo A, Roglans N, Sánchez RM, Vázquez-Carrera M, Laguna JC, Pedro-Botet J, Alegret M
Experimental biology and medicine (Maywood, N.J.) 2008 Dec;233(12):1572-82
Experimental biology and medicine (Maywood, N.J.) 2008 Dec;233(12):1572-82
Discontinuous movement of mRNP particles in nucleoplasmic regions devoid of chromatin.
Siebrasse JP, Veith R, Dobay A, Leonhardt H, Daneholt B, Kubitscheck U
Proceedings of the National Academy of Sciences of the United States of America 2008 Dec 23;105(51):20291-6
Proceedings of the National Academy of Sciences of the United States of America 2008 Dec 23;105(51):20291-6
Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors.
Li L, Thompson PA, Kitchens RL
Journal of lipid research 2008 Aug;49(8):1782-93
Journal of lipid research 2008 Aug;49(8):1782-93
Xanthophylls are preferentially taken up compared with beta-carotene by retinal cells via a SRBI-dependent mechanism.
During A, Doraiswamy S, Harrison EH
Journal of lipid research 2008 Aug;49(8):1715-24
Journal of lipid research 2008 Aug;49(8):1715-24
Failure of adrenal corticosterone production in POMC-deficient mice results from lack of integrated effects of POMC peptides on multiple factors.
Karpac J, Czyzewska K, Kern A, Brush RS, Anderson RE, Hochgeschwender U
American journal of physiology. Endocrinology and metabolism 2008 Aug;295(2):E446-55
American journal of physiology. Endocrinology and metabolism 2008 Aug;295(2):E446-55
Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells.
Barth H, Schnober EK, Neumann-Haefelin C, Thumann C, Zeisel MB, Diepolder HM, Hu Z, Liang TJ, Blum HE, Thimme R, Lambotin M, Baumert TF
Journal of virology 2008 Apr;82(7):3466-79
Journal of virology 2008 Apr;82(7):3466-79
Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters.
Ashraf MZ, Kar NS, Chen X, Choi J, Salomon RG, Febbraio M, Podrez EA
The Journal of biological chemistry 2008 Apr 18;283(16):10408-14
The Journal of biological chemistry 2008 Apr 18;283(16):10408-14
Mechanisms of provitamin A (carotenoid) and vitamin A (retinol) transport into and out of intestinal Caco-2 cells.
During A, Harrison EH
Journal of lipid research 2007 Oct;48(10):2283-94
Journal of lipid research 2007 Oct;48(10):2283-94
SCP-2/SCP-x gene ablation alters lipid raft domains in primary cultured mouse hepatocytes.
Atshaves BP, McIntosh AL, Payne HR, Gallegos AM, Landrock K, Maeda N, Kier AB, Schroeder F
Journal of lipid research 2007 Oct;48(10):2193-211
Journal of lipid research 2007 Oct;48(10):2193-211
Paraoxonase 1 response to a high-fat diet: gender differences in the factors involved.
Thomàs-Moyà E, Gianotti M, Proenza AM, Lladó I
Molecular medicine (Cambridge, Mass.) 2007 Mar-Apr;13(3-4):203-9
Molecular medicine (Cambridge, Mass.) 2007 Mar-Apr;13(3-4):203-9
Effects of apoA-V on HDL and VLDL metabolism in APOC3 transgenic mice.
Qu S, Perdomo G, Su D, D'Souza FM, Shachter NS, Dong HH
Journal of lipid research 2007 Jul;48(7):1476-87
Journal of lipid research 2007 Jul;48(7):1476-87
E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.
Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G
Molecular and cellular biology 2007 Jan;27(1):65-78
Molecular and cellular biology 2007 Jan;27(1):65-78
SR-BI undergoes cholesterol-stimulated transcytosis to the bile canaliculus in polarized WIF-B cells.
Harder CJ, Meng A, Rippstein P, McBride HM, McPherson R
The Journal of biological chemistry 2007 Jan 12;282(2):1445-55
The Journal of biological chemistry 2007 Jan 12;282(2):1445-55
Intrauterine growth restriction is associated with alterations in placental lipoprotein receptors and maternal lipoprotein composition.
Wadsack C, Tabano S, Maier A, Hiden U, Alvino G, Cozzi V, Hüttinger M, Schneider WJ, Lang U, Cetin I, Desoye G
American journal of physiology. Endocrinology and metabolism 2007 Feb;292(2):E476-84
American journal of physiology. Endocrinology and metabolism 2007 Feb;292(2):E476-84
Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81.
Zeisel MB, Koutsoudakis G, Schnober EK, Haberstroh A, Blum HE, Cosset FL, Wakita T, Jaeck D, Doffoel M, Royer C, Soulier E, Schvoerer E, Schuster C, Stoll-Keller F, Bartenschlager R, Pietschmann T, Barth H, Baumert TF
Hepatology (Baltimore, Md.) 2007 Dec;46(6):1722-31
Hepatology (Baltimore, Md.) 2007 Dec;46(6):1722-31
NO-1886 upregulates ATP binding cassette transporter A1 and inhibits diet-induced atherosclerosis in Chinese Bama minipigs.
Zhang C, Yin W, Liao D, Huang L, Tang C, Tsutsumi K, Wang Z, Liu Y, Li Q, Hou H, Cai M, Xiao J
Journal of lipid research 2006 Sep;47(9):2055-63
Journal of lipid research 2006 Sep;47(9):2055-63
The age-related paraoxonase 1 response is altered by long-term caloric restriction in male and female rats.
Thomàs-Moyà E, Gianotti M, Proenza AM, Lladó I
Journal of lipid research 2006 Sep;47(9):2042-8
Journal of lipid research 2006 Sep;47(9):2042-8
The predominance of one of the SR-BI isoforms is associated with increased esterified cholesterol levels not apoptosis in mink testis.
Akpovi CD, Yoon SR, Vitale ML, Pelletier RM
Journal of lipid research 2006 Oct;47(10):2233-47
Journal of lipid research 2006 Oct;47(10):2233-47
Localization and role of NPC1L1 in cholesterol absorption in human intestine.
Sané AT, Sinnett D, Delvin E, Bendayan M, Marcil V, Ménard D, Beaulieu JF, Levy E
Journal of lipid research 2006 Oct;47(10):2112-20
Journal of lipid research 2006 Oct;47(10):2112-20
Hepatitis C virus E2 links soluble human CD81 and SR-B1 protein.
Heo TH, Lee SM, Bartosch B, Cosset FL, Kang CY
Virus research 2006 Oct;121(1):58-64
Virus research 2006 Oct;121(1):58-64
Persistent hepatitis C virus infection in vitro: coevolution of virus and host.
Zhong J, Gastaminza P, Chung J, Stamataki Z, Isogawa M, Cheng G, McKeating JA, Chisari FV
Journal of virology 2006 Nov;80(22):11082-93
Journal of virology 2006 Nov;80(22):11082-93
LDL and cAMP cooperate to regulate the functional expression of the LRP in rat ovarian granulosa cells.
Azhar S, Medicherla S, Shen WJ, Fujioka Y, Fong LG, Reaven E, Cooper AD
Journal of lipid research 2006 Nov;47(11):2538-50
Journal of lipid research 2006 Nov;47(11):2538-50
Hepatic SR-BI-mediated cholesteryl ester selective uptake occurs with unaltered efficiency in the absence of cellular energy.
Harder CJ, Vassiliou G, McBride HM, McPherson R
Journal of lipid research 2006 Mar;47(3):492-503
Journal of lipid research 2006 Mar;47(3):492-503
Localization of oxidized phosphatidylcholine in nonalcoholic fatty liver disease: impact on disease progression.
Ikura Y, Ohsawa M, Suekane T, Fukushima H, Itabe H, Jomura H, Nishiguchi S, Inoue T, Naruko T, Ehara S, Kawada N, Arakawa T, Ueda M
Hepatology (Baltimore, Md.) 2006 Mar;43(3):506-14
Hepatology (Baltimore, Md.) 2006 Mar;43(3):506-14
Effects of hepatic expression of the high-density lipoprotein receptor SR-BI on lipoprotein metabolism and female fertility.
Yesilaltay A, Morales MG, Amigo L, Zanlungo S, Rigotti A, Karackattu SL, Donahee MH, Kozarsky KF, Krieger M
Endocrinology 2006 Apr;147(4):1577-88
Endocrinology 2006 Apr;147(4):1577-88
Insulin and angiotensin II induce the translocation of scavenger receptor class B, type I from intracellular sites to the plasma membrane of adipocytes.
Tondu AL, Robichon C, Yvan-Charvet L, Donne N, Le Liepvre X, Hajduch E, Ferré P, Dugail I, Dagher G
The Journal of biological chemistry 2005 Sep 30;280(39):33536-40
The Journal of biological chemistry 2005 Sep 30;280(39):33536-40
Scavenger receptor class B type I and hepatitis C virus infection of primary tupaia hepatocytes.
Barth H, Cerino R, Arcuri M, Hoffmann M, Schürmann P, Adah MI, Gissler B, Zhao X, Ghisetti V, Lavezzo B, Blum HE, von Weizsäcker F, Vitelli A, Scarselli E, Baumert TF
Journal of virology 2005 May;79(9):5774-85
Journal of virology 2005 May;79(9):5774-85
Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells.
Lalanne F, Lambert G, Amar MJ, Chétiveaux M, Zaïr Y, Jarnoux AL, Ouguerram K, Friburg J, Seidah NG, Brewer HB Jr, Krempf M, Costet P
Journal of lipid research 2005 Jun;46(6):1312-9
Journal of lipid research 2005 Jun;46(6):1312-9
Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors.
Lemieux C, Gélinas Y, Lalonde J, Labrie F, Cianflone K, Deshaies Y
Journal of lipid research 2005 Jun;46(6):1285-94
Journal of lipid research 2005 Jun;46(6):1285-94
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.
Johansson L, Rudling M, Scanlan TS, Lundåsen T, Webb P, Baxter J, Angelin B, Parini P
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 19;102(29):10297-302
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 19;102(29):10297-302
Physiological importance of SR-BI in the in vivo metabolism of human HDL and LDL in male and female mice.
Brodeur MR, Luangrath V, Bourret G, Falstrault L, Brissette L
Journal of lipid research 2005 Apr;46(4):687-96
Journal of lipid research 2005 Apr;46(4):687-96
Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104).
Han J, Parsons M, Zhou X, Nicholson AC, Gotto AM Jr, Hajjar DP
Circulation 2004 Nov 30;110(22):3472-9
Circulation 2004 Nov 30;110(22):3472-9
Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol.
Sehayek E, Wang R, Ono JG, Zinchuk VS, Duncan EM, Shefer S, Vance DE, Ananthanarayanan M, Chait BT, Breslow JL
Journal of lipid research 2003 Sep;44(9):1605-13
Journal of lipid research 2003 Sep;44(9):1605-13
Acute tubular injury causes dysregulation of cellular cholesterol transport proteins.
Zager RA, Johnson AC, Hanson SY, Shah VO
The American journal of pathology 2003 Jul;163(1):313-20
The American journal of pathology 2003 Jul;163(1):313-20
Sepsis syndrome stimulates proximal tubule cholesterol synthesis and suppresses the SR-B1 cholesterol transporter.
Zager RA, Johnson AC, Hanson SY
Kidney international 2003 Jan;63(1):123-33
Kidney international 2003 Jan;63(1):123-33
Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression.
Johnson AC, Yabu JM, Hanson S, Shah VO, Zager RA
The American journal of pathology 2003 Jan;162(1):283-91
The American journal of pathology 2003 Jan;162(1):283-91
Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins.
Wadsack C, Hrzenjak A, Hammer A, Hirschmugl B, Levak-Frank S, Desoye G, Sattler W, Malle E
European journal of biochemistry 2003 Feb;270(3):451-62
European journal of biochemistry 2003 Feb;270(3):451-62
Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins.
Wadsack C, Hrzenjak A, Hammer A, Hirschmugl B, Levak-Frank S, Desoye G, Sattler W, Malle E
European journal of biochemistry 2003 Feb;270(3):451-62
European journal of biochemistry 2003 Feb;270(3):451-62
Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade.
Zager RA, Johnson AC, Hanson SY
American journal of physiology. Renal physiology 2003 Dec;285(6):F1092-9
American journal of physiology. Renal physiology 2003 Dec;285(6):F1092-9
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.
Scarselli E, Ansuini H, Cerino R, Roccasecca RM, Acali S, Filocamo G, Traboni C, Nicosia A, Cortese R, Vitelli A
The EMBO journal 2002 Oct 1;21(19):5017-25
The EMBO journal 2002 Oct 1;21(19):5017-25
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus.
Scarselli E, Ansuini H, Cerino R, Roccasecca RM, Acali S, Filocamo G, Traboni C, Nicosia A, Cortese R, Vitelli A
The EMBO journal 2002 Oct 1;21(19):5017-25
The EMBO journal 2002 Oct 1;21(19):5017-25
Effects of lipoprotein lipase on uptake and transcytosis of low density lipoprotein (LDL) and LDL-associated alpha-tocopherol in a porcine in vitro blood-brain barrier model.
Goti D, Balazs Z, Panzenboeck U, Hrzenjak A, Reicher H, Wagner E, Zechner R, Malle E, Sattler W
The Journal of biological chemistry 2002 Aug 9;277(32):28537-44
The Journal of biological chemistry 2002 Aug 9;277(32):28537-44
p21-activated kinase-1 (PAK1) inhibition of the human scavenger receptor class B, type I promoter in macrophages is independent of PAK1 kinase activity, but requires the GTPase-binding domain.
Hullinger TG, Panek RL, Xu X, Karathanasis SK
The Journal of biological chemistry 2001 Dec 14;276(50):46807-14
The Journal of biological chemistry 2001 Dec 14;276(50):46807-14
Regulation by vitamin E of the scavenger receptor BI in rat liver and HepG2 cells.
Witt W, Kolleck I, Fechner H, Sinha P, Rüstow B
Journal of lipid research 2000 Dec;41(12):2009-16
Journal of lipid research 2000 Dec;41(12):2009-16
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Supportive validation
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- Western Blot: SR-BI Antibody [NB400-104] - Detection of SR-BI in rat H4IIE total cell lysates and plasma membrane proteins. Photo courtesy of product review by verified customer.
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- Simple Western: SR-BI Antibody [NB400-104] - Image shows a specific band for SR-BI in 0.5 mg/mL of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.
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- Western Blot: SR-BI Antibody [NB400-104] - Analysis using the HRP-conjugate of NB400-104. Detection of SR-BI in 25 ug of mouse liver lysate, using NB400-104 (lotJ) at a 1:1000 dilution, shows distinct band at 82 kDa.
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- Western Blot: SR-BI Antibody [NB400-104] - SR-BI antibody was tested in human adrenal cell lysate.
Supportive validation
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- Immunohistochemistry: SR-BI Antibody [NB400-104] - Immunolocalization of SR-BI in adult mink testis using NB400-104. SR-BI labeling is visible at the surface and along the outline of the large vacuole. Photo courtesy of R.M. Pelletier, University of Montreal.
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- Immunohistochemistry-Paraffin: SR-BI Antibody [NB400-104] - FFPE tissue section of mouse liver using SR-BI antibody (Lot 8310) at 1:300 dilution with HRP-DAB detection and hematoxylin counterstaining. The antibody generated a specific membrane signal of SR-BI protein in the murine hepatocytes.
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- Immunohistochemistry-Paraffin: SR-BI Antibody [NB400-104] - FFPE tissue section of mouse liver using SR-BI antibody (Lot R-4) at 1:300 dilution with HRP-DAB detection and hematoxylin counterstaining. The antibody generated mainly a membranous signal of SR-BI protein in the murine hepatocytes.
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- Immunohistochemistry-Paraffin: SR-BI Antibody [NB400-104] - Staining of human adrenal cortex.
Supportive validation
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- Flow Cytometry: SR-BI Antibody [NB400-104] - SR-B1 staining of human adipose tissue macrophage populations compared to isotype control (orange). Image from verified customer review. Image using the DyLight 550 form of this antibody.
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- Flow Cytometry: SR-BI Antibody [NB400-104] - Analysis of Huh7 and HepG2 cells using SR-B1 antibody NB400-104. Courtesy of Bruno Sainz, Jr., PhD, University of Illinois at Chicago.
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- Flow Cytometry: SR-BI Antibody [NB400-104] - An intracellular stain was performed on HeLa cells with SR-BI antibody NB400-104AF488 (blue) and a matched isotype control NBP2-24893AF488 (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 488.
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- Flow Cytometry: SR-BI Antibody [NB400-104] - An intracellular stain was performed on HeLa cells with SR-BI antibody NB400-104PE (blue) and a matched isotype control NBP2-24893PE (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 1 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Phycoerythrin.
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- Flow Cytometry: SR-BI Antibody [NB400-104] - An intracellular stain was performed on A549 cells with SR-BI antibody NB400-104AF488 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 488.
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- Flow Cytometry: SR-BI Antibody [NB400-104] - An intracellular stain was performed on SK-MEL-28 cells with SR-BI antibody NB400-104PE (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Phycoerythrin.
