Explore
Validate
LearnABIN152880
antibody from antibodies-online
Targeting: SCARB1
CD36L1, CLA-1, CLA1, SR-BI, SRB1
Western blot
Immunocytochemistry
Immunoprecipitation Immunohistochemistry Flow cytometry Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [82]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN152880 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 450-509), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Bovine, Simian
- Host
- Rabbit
- Epitope
- C-Term, AA 450-509
- Vial size
- 0.1 mL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references High density lipoprotein modulates osteocalcin expression in circulating monocytes: a potential protective mechanism for cardiovascular disease in type 1 diabetes.
SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation.
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.
Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis.
Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression.
Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice.
SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport.
Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.
A three-dimensional engineered artery model for in vitro atherosclerosis research.
Western blots.
Vitamin E secretion by Caco-2 monolayers to APOA1, but not to HDL, is vitamer selective.
CD36-related protein in Schistosoma japonicum: candidate mediator of selective cholesteryl ester uptake from high-density lipoprotein for egg maturation.
ATF3 expression in the corpus luteum: possible role in luteal regression.
Myeloid cell-specific serine palmitoyltransferase subunit 2 haploinsufficiency reduces murine atherosclerosis.
Functional characterization of newly-discovered mutations in human SR-BI.
Modified high-density lipoprotein modulates aldosterone release through scavenger receptors via extra cellular signal-regulated kinase and Janus kinase-dependent pathways.
Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development.
Induction of macrophage scavenger receptor type BI expression by tamoxifen and 4-hydroxytamoxifen.
Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport.
SR-BI, CD36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells.
Atherosclerosis in LDLR-knockout mice is inhibited, but not reversed, by the PPARgamma ligand pioglitazone.
Mechanism and regulatory function of CpG signaling via scavenger receptor B1 in primary B cells.
Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice.
Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion.
Scavenger receptor class B type I localizes to a late endosomal compartment.
Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo.
Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile.
A role for hepatic scavenger receptor class B, type I in decreasing high density lipoprotein levels in mice that lack phosphatidylethanolamine N-methyltransferase.
Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.
Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways.
Role of chondroitin sulphate in the uptake of beta-VLDL by brain cells.
Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1.
HMG-CoA reductase inhibition reverses LCAT and LDL receptor deficiencies and improves HDL in rats with chronic renal failure.
Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors.
Domain-specific lipid distribution in macrophage plasma membranes.
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.
Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate.
Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104).
Dynamin-2 regulates oxidized low-density lipoprotein-induced apoptosis of vascular smooth muscle cell.
Aberrant cholesterol transport and impaired steroidogenesis in Leydig cells lacking estrogen sulfotransferase.
Hepatic ABCG5 and ABCG8 overexpression increases hepatobiliary sterol transport but does not alter aortic atherosclerosis in transgenic mice.
Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet.
Apolipoprotein A-1 interaction with plasma membrane lipid rafts controls cholesterol export from macrophages.
Di(n-butyl) phthalate impairs cholesterol transport and steroidogenesis in the fetal rat testis through a rapid and reversible mechanism.
Increased CD36 protein as a response to defective insulin signaling in macrophages.
ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes.
Glycine 420 near the C-terminal transmembrane domain of SR-BI is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester.
Acyl-coenzyme A:cholesterol acyltransferase inhibition ameliorates proteinuria, hyperlipidemia, lecithin-cholesterol acyltransferase, SRB-1, and low-denisty lipoprotein receptor deficiencies in nephrotic syndrome.
Localization and regulation of SR-BI in membrane rafts of HepG2 cells.
Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein.
Ontogeny, immunolocalisation, distribution and function of SR-BI in the human intestine.
Absence of p21Waf1/Cip1/Sdi1 modulates macrophage differentiation and inflammatory response and protects against atherosclerosis.
Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS) uptake and LPS-induced pro-inflammatory cytokine responses in THP-1 monocyte cells.
Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function.
Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol.
Leptin induces the hepatic high density lipoprotein receptor scavenger receptor B type I (SR-BI) but not cholesterol 7alpha-hydroxylase (Cyp7a1) in leptin-deficient (ob/ob) mice.
Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1.
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles.
Phosphatidylinositol promotes cholesterol transport and excretion.
Evidence for a Trypanosoma brucei lipoprotein scavenger receptor.
The farnesoid X-receptor is an essential regulator of cholesterol homeostasis.
Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations.
Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice.
Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism.
Overexpression of SR-BI by adenoviral vector reverses the fibrateinduced hypercholesterolemia of apolipoprotein E-deficient mice.
Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels.
A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver.
ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells.
ApoE-dependent sterol efflux from macrophages is modulated by scavenger receptor class B type I expression.
Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements.
The expression of scavenger receptor class B, type I (SR-BI) and caveolin-1 in parenchymal and nonparenchymal liver cells.
Oxidized low density lipoprotein decreases macrophage expression of scavenger receptor B-I.
Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid.
Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine.
High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion.
Scavenger receptor class B type I-mediated reverse cholesterol transport is inhibited by advanced glycation end products.
Scavenger receptor-BI inhibits ATP-binding cassette transporter 1- mediated cholesterol efflux in macrophages.
Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.
Sterol carrier protein-2 alters high density lipoprotein-mediated cholesterol efflux.
Regulation by vitamin E of the scavenger receptor BI in rat liver and HepG2 cells.
High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach.
Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out mice.
Maddaloni E, Xia Y, Park K, D'Eon S, Tinsley LJ, St-Louis R, Khamaisi M, Li Q, King GL, Keenan HA
Cardiovascular diabetology 2017 Sep 16;16(1):116
Cardiovascular diabetology 2017 Sep 16;16(1):116
SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation.
Tsugita M, Morimoto N, Tashiro M, Kinoshita K, Nakayama M
Cell reports 2017 Jan 31;18(5):1298-1311
Cell reports 2017 Jan 31;18(5):1298-1311
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.
Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J
Nature communications 2017 Apr 19;8:15010
Nature communications 2017 Apr 19;8:15010
Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis.
Conlon DM, Thomas T, Fedotova T, Hernandez-Ono A, Di Paolo G, Chan RB, Ruggles K, Gibeley S, Liu J, Ginsberg HN
The Journal of clinical investigation 2016 Oct 3;126(10):3852-3867
The Journal of clinical investigation 2016 Oct 3;126(10):3852-3867
Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression.
Pasterk L, Lemesch S, Leber B, Trieb M, Curcic S, Stadlbauer V, Schuligoi R, Schicho R, Heinemann A, Marsche G
Scientific reports 2016 Feb 24;6:22104
Scientific reports 2016 Feb 24;6:22104
Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice.
Vaisman BL, Vishnyakova TG, Freeman LA, Amar MJ, Demosky SJ, Liu C, Stonik JA, Sampson ML, Pryor M, Bocharov AV, Eggerman TL, Patterson AP, Remaley AT
BioMed research international 2015;2015:607120
BioMed research international 2015;2015:607120
SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport.
Kartz GA, Holme RL, Nicholson K, Sahoo D
Biochemistry 2014 Oct 7;53(39):6173-82
Biochemistry 2014 Oct 7;53(39):6173-82
Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.
Béaslas O, Metso J, Nissilä E, Laurila PP, Kaiharju E, Batchu KC, Kaipiainen L, Mäyränpää MI, Yan D, Gylling H, Jauhiainen M, Olkkonen VM
PloS one 2013;8(3):e58856
PloS one 2013;8(3):e58856
A three-dimensional engineered artery model for in vitro atherosclerosis research.
Robert J, Weber B, Frese L, Emmert MY, Schmidt D, von Eckardstein A, Rohrer L, Hoerstrup SP
PloS one 2013;8(11):e79821
PloS one 2013;8(11):e79821
Western blots.
Freeman LA
Methods in molecular biology (Clifton, N.J.) 2013;1027:369-85
Methods in molecular biology (Clifton, N.J.) 2013;1027:369-85
Vitamin E secretion by Caco-2 monolayers to APOA1, but not to HDL, is vitamer selective.
Nicod N, Parker RS
The Journal of nutrition 2013 Oct;143(10):1565-72
The Journal of nutrition 2013 Oct;143(10):1565-72
CD36-related protein in Schistosoma japonicum: candidate mediator of selective cholesteryl ester uptake from high-density lipoprotein for egg maturation.
Okumura-Noji K, Miura Y, Lu R, Asai K, Ohta N, Brindley PJ, Yokoyama S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Mar;27(3):1236-44
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Mar;27(3):1236-44
ATF3 expression in the corpus luteum: possible role in luteal regression.
Mao D, Hou X, Talbott H, Cushman R, Cupp A, Davis JS
Molecular endocrinology (Baltimore, Md.) 2013 Dec;27(12):2066-79
Molecular endocrinology (Baltimore, Md.) 2013 Dec;27(12):2066-79
Myeloid cell-specific serine palmitoyltransferase subunit 2 haploinsufficiency reduces murine atherosclerosis.
Chakraborty M, Lou C, Huan C, Kuo MS, Park TS, Cao G, Jiang XC
The Journal of clinical investigation 2013 Apr;123(4):1784-97
The Journal of clinical investigation 2013 Apr;123(4):1784-97
Functional characterization of newly-discovered mutations in human SR-BI.
Chadwick AC, Sahoo D
PloS one 2012;7(9):e45660
PloS one 2012;7(9):e45660
Modified high-density lipoprotein modulates aldosterone release through scavenger receptors via extra cellular signal-regulated kinase and Janus kinase-dependent pathways.
Saha S, Graessler J, Schwarz PE, Goettsch C, Bornstein SR, Kopprasch S
Molecular and cellular biochemistry 2012 Jul;366(1-2):1-10
Molecular and cellular biochemistry 2012 Jul;366(1-2):1-10
Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development.
Kushiyama A, Okubo H, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, Nakatsu Y, Kamata H, Kawazu S, Higashi Y, Kurihara H, Asano T
Arteriosclerosis, thrombosis, and vascular biology 2012 Feb;32(2):291-8
Arteriosclerosis, thrombosis, and vascular biology 2012 Feb;32(2):291-8
Induction of macrophage scavenger receptor type BI expression by tamoxifen and 4-hydroxytamoxifen.
Dong P, Xie T, Zhou X, Hu W, Chen Y, Duan Y, Li X, Han J
Atherosclerosis 2011 Oct;218(2):435-42
Atherosclerosis 2011 Oct;218(2):435-42
Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport.
Papale GA, Hanson PJ, Sahoo D
Biochemistry 2011 Jul 19;50(28):6245-54
Biochemistry 2011 Jul 19;50(28):6245-54
SR-BI, CD36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells.
Truong TQ, Aubin D, Falstrault L, Brodeur MR, Brissette L
Cell biochemistry and function 2010 Aug;28(6):480-9
Cell biochemistry and function 2010 Aug;28(6):480-9
Atherosclerosis in LDLR-knockout mice is inhibited, but not reversed, by the PPARgamma ligand pioglitazone.
Nakaya H, Summers BD, Nicholson AC, Gotto AM Jr, Hajjar DP, Han J
The American journal of pathology 2009 Jun;174(6):2007-14
The American journal of pathology 2009 Jun;174(6):2007-14
Mechanism and regulatory function of CpG signaling via scavenger receptor B1 in primary B cells.
Zhu P, Liu X, Treml LS, Cancro MP, Freedman BD
The Journal of biological chemistry 2009 Aug 21;284(34):22878-87
The Journal of biological chemistry 2009 Aug 21;284(34):22878-87
Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice.
Labonté ED, Camarota LM, Rojas JC, Jandacek RJ, Gilham DE, Davies JP, Ioannou YA, Tso P, Hui DY, Howles PN
American journal of physiology. Gastrointestinal and liver physiology 2008 Oct;295(4):G776-83
American journal of physiology. Gastrointestinal and liver physiology 2008 Oct;295(4):G776-83
Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretion.
Tietge UJ, Nijstad N, Havinga R, Baller JF, van der Sluijs FH, Bloks VW, Gautier T, Kuipers F
Journal of lipid research 2008 Mar;49(3):563-71
Journal of lipid research 2008 Mar;49(3):563-71
Scavenger receptor class B type I localizes to a late endosomal compartment.
Ahras M, Naing T, McPherson R
Journal of lipid research 2008 Jul;49(7):1569-76
Journal of lipid research 2008 Jul;49(7):1569-76
Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo.
Van Eck M, Hoekstra M, Out R, Bos IS, Kruijt JK, Hildebrand RB, Van Berkel TJ
Journal of lipid research 2008 Jan;49(1):136-46
Journal of lipid research 2008 Jan;49(1):136-46
Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile.
Hashimoto K, Suzuki H, Taniguchi K, Noguchi T, Yohda M, Odaka M
The Journal of biological chemistry 2008 Dec 26;283(52):36617-23
The Journal of biological chemistry 2008 Dec 26;283(52):36617-23
A role for hepatic scavenger receptor class B, type I in decreasing high density lipoprotein levels in mice that lack phosphatidylethanolamine N-methyltransferase.
Robichaud JC, Francis GA, Vance DE
The Journal of biological chemistry 2008 Dec 19;283(51):35496-506
The Journal of biological chemistry 2008 Dec 19;283(51):35496-506
Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.
Labonté ED, Howles PN, Granholm NA, Rojas JC, Davies JP, Ioannou YA, Hui DY
Biochimica et biophysica acta 2007 Sep;1771(9):1132-9
Biochimica et biophysica acta 2007 Sep;1771(9):1132-9
Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways.
Zhang Y, Ahmed AM, McFarlane N, Capone C, Boreham DR, Truant R, Igdoura SA, Trigatti BL
Journal of lipid research 2007 Feb;48(2):405-16
Journal of lipid research 2007 Feb;48(2):405-16
Role of chondroitin sulphate in the uptake of beta-VLDL by brain cells.
Rapp A, Hüttinger M
The European journal of neuroscience 2005 Sep;22(6):1400-8
The European journal of neuroscience 2005 Sep;22(6):1400-8
Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1.
Nakamura T, Shibata N, Nishimoto-Shibata T, Feng D, Ikemoto M, Motojima K, Iso-O N, Tsukamoto K, Tsujimoto M, Arai H
Proceedings of the National Academy of Sciences of the United States of America 2005 Sep 20;102(38):13404-9
Proceedings of the National Academy of Sciences of the United States of America 2005 Sep 20;102(38):13404-9
HMG-CoA reductase inhibition reverses LCAT and LDL receptor deficiencies and improves HDL in rats with chronic renal failure.
Liang K, Kim CH, Vaziri ND
American journal of physiology. Renal physiology 2005 Mar;288(3):F539-44
American journal of physiology. Renal physiology 2005 Mar;288(3):F539-44
Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors.
Lemieux C, Gélinas Y, Lalonde J, Labrie F, Cianflone K, Deshaies Y
Journal of lipid research 2005 Jun;46(6):1285-94
Journal of lipid research 2005 Jun;46(6):1285-94
Domain-specific lipid distribution in macrophage plasma membranes.
Gaus K, Rodriguez M, Ruberu KR, Gelissen I, Sloane TM, Kritharides L, Jessup W
Journal of lipid research 2005 Jul;46(7):1526-38
Journal of lipid research 2005 Jul;46(7):1526-38
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.
Johansson L, Rudling M, Scanlan TS, Lundåsen T, Webb P, Baxter J, Angelin B, Parini P
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 19;102(29):10297-302
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 19;102(29):10297-302
Dose-dependent alterations in gene expression and testosterone synthesis in the fetal testes of male rats exposed to di (n-butyl) phthalate.
Lehmann KP, Phillips S, Sar M, Foster PM, Gaido KW
Toxicological sciences : an official journal of the Society of Toxicology 2004 Sep;81(1):60-8
Toxicological sciences : an official journal of the Society of Toxicology 2004 Sep;81(1):60-8
Functional interplay between the macrophage scavenger receptor class B type I and pitavastatin (NK-104).
Han J, Parsons M, Zhou X, Nicholson AC, Gotto AM Jr, Hajjar DP
Circulation 2004 Nov 30;110(22):3472-9
Circulation 2004 Nov 30;110(22):3472-9
Dynamin-2 regulates oxidized low-density lipoprotein-induced apoptosis of vascular smooth muscle cell.
Kashiwakura Y, Watanabe M, Kusumi N, Sumiyoshi K, Nasu Y, Yamada H, Sawamura T, Kumon H, Takei K, Daida H
Circulation 2004 Nov 23;110(21):3329-34
Circulation 2004 Nov 23;110(21):3329-34
Aberrant cholesterol transport and impaired steroidogenesis in Leydig cells lacking estrogen sulfotransferase.
Tong MH, Christenson LK, Song WC
Endocrinology 2004 May;145(5):2487-97
Endocrinology 2004 May;145(5):2487-97
Hepatic ABCG5 and ABCG8 overexpression increases hepatobiliary sterol transport but does not alter aortic atherosclerosis in transgenic mice.
Wu JE, Basso F, Shamburek RD, Amar MJ, Vaisman B, Szakacs G, Joyce C, Tansey T, Freeman L, Paigen BJ, Thomas F, Brewer HB Jr, Santamarina-Fojo S
The Journal of biological chemistry 2004 May 28;279(22):22913-25
The Journal of biological chemistry 2004 May 28;279(22):22913-25
Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet.
Akiyama TE, Lambert G, Nicol CJ, Matsusue K, Peters JM, Brewer HB Jr, Gonzalez FJ
The Journal of biological chemistry 2004 May 14;279(20):20874-81
The Journal of biological chemistry 2004 May 14;279(20):20874-81
Apolipoprotein A-1 interaction with plasma membrane lipid rafts controls cholesterol export from macrophages.
Gaus K, Kritharides L, Schmitz G, Boettcher A, Drobnik W, Langmann T, Quinn CM, Death A, Dean RT, Jessup W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Mar;18(3):574-6
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Mar;18(3):574-6
Di(n-butyl) phthalate impairs cholesterol transport and steroidogenesis in the fetal rat testis through a rapid and reversible mechanism.
Thompson CJ, Ross SM, Gaido KW
Endocrinology 2004 Mar;145(3):1227-37
Endocrinology 2004 Mar;145(3):1227-37
Increased CD36 protein as a response to defective insulin signaling in macrophages.
Liang CP, Han S, Okamoto H, Carnemolla R, Tabas I, Accili D, Tall AR
The Journal of clinical investigation 2004 Mar;113(5):764-73
The Journal of clinical investigation 2004 Mar;113(5):764-73
ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes.
Sahoo D, Trischuk TC, Chan T, Drover VA, Ho S, Chimini G, Agellon LB, Agnihotri R, Francis GA, Lehner R
Journal of lipid research 2004 Jun;45(6):1122-31
Journal of lipid research 2004 Jun;45(6):1122-31
Glycine 420 near the C-terminal transmembrane domain of SR-BI is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester.
Parathath S, Sahoo D, Darlington YF, Peng Y, Collins HL, Rothblat GH, Williams DL, Connelly MA
The Journal of biological chemistry 2004 Jun 11;279(24):24976-85
The Journal of biological chemistry 2004 Jun 11;279(24):24976-85
Acyl-coenzyme A:cholesterol acyltransferase inhibition ameliorates proteinuria, hyperlipidemia, lecithin-cholesterol acyltransferase, SRB-1, and low-denisty lipoprotein receptor deficiencies in nephrotic syndrome.
Vaziri ND, Liang KH
Circulation 2004 Jul 27;110(4):419-25
Circulation 2004 Jul 27;110(4):419-25
Localization and regulation of SR-BI in membrane rafts of HepG2 cells.
Rhainds D, Bourgeois P, Bourret G, Huard K, Falstrault L, Brissette L
Journal of cell science 2004 Jul 1;117(Pt 15):3095-105
Journal of cell science 2004 Jul 1;117(Pt 15):3095-105
Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein.
Peng Y, Akmentin W, Connelly MA, Lund-Katz S, Phillips MC, Williams DL
Molecular biology of the cell 2004 Jan;15(1):384-96
Molecular biology of the cell 2004 Jan;15(1):384-96
Ontogeny, immunolocalisation, distribution and function of SR-BI in the human intestine.
Levy E, Ménard D, Suc I, Delvin E, Marcil V, Brissette L, Thibault L, Bendayan M
Journal of cell science 2004 Jan 15;117(Pt 2):327-37
Journal of cell science 2004 Jan 15;117(Pt 2):327-37
Absence of p21Waf1/Cip1/Sdi1 modulates macrophage differentiation and inflammatory response and protects against atherosclerosis.
Merched AJ, Chan L
Circulation 2004 Dec 21;110(25):3830-41
Circulation 2004 Dec 21;110(25):3830-41
Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS) uptake and LPS-induced pro-inflammatory cytokine responses in THP-1 monocyte cells.
Bocharov AV, Baranova IN, Vishnyakova TG, Remaley AT, Csako G, Thomas F, Patterson AP, Eggerman TL
The Journal of biological chemistry 2004 Aug 20;279(34):36072-82
The Journal of biological chemistry 2004 Aug 20;279(34):36072-82
Differential requirement for steroidogenic factor-1 gene dosage in adrenal development versus endocrine function.
Bland ML, Fowkes RC, Ingraham HA
Molecular endocrinology (Baltimore, Md.) 2004 Apr;18(4):941-52
Molecular endocrinology (Baltimore, Md.) 2004 Apr;18(4):941-52
Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol.
Sehayek E, Wang R, Ono JG, Zinchuk VS, Duncan EM, Shefer S, Vance DE, Ananthanarayanan M, Chait BT, Breslow JL
Journal of lipid research 2003 Sep;44(9):1605-13
Journal of lipid research 2003 Sep;44(9):1605-13
Leptin induces the hepatic high density lipoprotein receptor scavenger receptor B type I (SR-BI) but not cholesterol 7alpha-hydroxylase (Cyp7a1) in leptin-deficient (ob/ob) mice.
Lundåsen T, Liao W, Angelin B, Rudling M
The Journal of biological chemistry 2003 Oct 31;278(44):43224-8
The Journal of biological chemistry 2003 Oct 31;278(44):43224-8
Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1.
Vishnyakova TG, Bocharov AV, Baranova IN, Chen Z, Remaley AT, Csako G, Eggerman TL, Patterson AP
The Journal of biological chemistry 2003 Jun 20;278(25):22771-80
The Journal of biological chemistry 2003 Jun 20;278(25):22771-80
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles.
Hsu M, Zhang J, Flint M, Logvinoff C, Cheng-Mayer C, Rice CM, McKeating JA
Proceedings of the National Academy of Sciences of the United States of America 2003 Jun 10;100(12):7271-6
Proceedings of the National Academy of Sciences of the United States of America 2003 Jun 10;100(12):7271-6
Phosphatidylinositol promotes cholesterol transport and excretion.
Burgess JW, Boucher J, Neville TA, Rouillard P, Stamler C, Zachariah S, Sparks DL
Journal of lipid research 2003 Jul;44(7):1355-63
Journal of lipid research 2003 Jul;44(7):1355-63
Evidence for a Trypanosoma brucei lipoprotein scavenger receptor.
Green HP, Del Pilar Molina Portela M, St Jean EN, Lugli EB, Raper J
The Journal of biological chemistry 2003 Jan 3;278(1):422-7
The Journal of biological chemistry 2003 Jan 3;278(1):422-7
The farnesoid X-receptor is an essential regulator of cholesterol homeostasis.
Lambert G, Amar MJ, Guo G, Brewer HB Jr, Gonzalez FJ, Sinal CJ
The Journal of biological chemistry 2003 Jan 24;278(4):2563-70
The Journal of biological chemistry 2003 Jan 24;278(4):2563-70
Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations.
Basso F, Freeman L, Knapper CL, Remaley A, Stonik J, Neufeld EB, Tansey T, Amar MJ, Fruchart-Najib J, Duverger N, Santamarina-Fojo S, Brewer HB Jr
Journal of lipid research 2003 Feb;44(2):296-302
Journal of lipid research 2003 Feb;44(2):296-302
Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice.
Willner EL, Tow B, Buhman KK, Wilson M, Sanan DA, Rudel LL, Farese RV Jr
Proceedings of the National Academy of Sciences of the United States of America 2003 Feb 4;100(3):1262-7
Proceedings of the National Academy of Sciences of the United States of America 2003 Feb 4;100(3):1262-7
Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism.
Kocher O, Yesilaltay A, Cirovic C, Pal R, Rigotti A, Krieger M
The Journal of biological chemistry 2003 Dec 26;278(52):52820-5
The Journal of biological chemistry 2003 Dec 26;278(52):52820-5
Overexpression of SR-BI by adenoviral vector reverses the fibrateinduced hypercholesterolemia of apolipoprotein E-deficient mice.
Fu T, Kozarsky KF, Borensztajn J
The Journal of biological chemistry 2003 Dec 26;278(52):52559-63
The Journal of biological chemistry 2003 Dec 26;278(52):52559-63
Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels.
Silver DL, Wang N, Vogel S
The Journal of biological chemistry 2003 Aug 1;278(31):28528-32
The Journal of biological chemistry 2003 Aug 1;278(31):28528-32
A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver.
Silver DL
The Journal of biological chemistry 2002 Sep 13;277(37):34042-7
The Journal of biological chemistry 2002 Sep 13;277(37):34042-7
ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells.
Panzenboeck U, Balazs Z, Sovic A, Hrzenjak A, Levak-Frank S, Wintersperger A, Malle E, Sattler W
The Journal of biological chemistry 2002 Nov 8;277(45):42781-9
The Journal of biological chemistry 2002 Nov 8;277(45):42781-9
ApoE-dependent sterol efflux from macrophages is modulated by scavenger receptor class B type I expression.
Huang ZH, Mazzone T
Journal of lipid research 2002 Mar;43(3):375-82
Journal of lipid research 2002 Mar;43(3):375-82
Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements.
Tsuruoka H, Khovidhunkit W, Brown BE, Fluhr JW, Elias PM, Feingold KR
The Journal of biological chemistry 2002 Jan 25;277(4):2916-22
The Journal of biological chemistry 2002 Jan 25;277(4):2916-22
The expression of scavenger receptor class B, type I (SR-BI) and caveolin-1 in parenchymal and nonparenchymal liver cells.
Malerød L, Juvet K, Gjøen T, Berg T
Cell and tissue research 2002 Feb;307(2):173-80
Cell and tissue research 2002 Feb;307(2):173-80
Oxidized low density lipoprotein decreases macrophage expression of scavenger receptor B-I.
Han J, Nicholson AC, Zhou X, Feng J, Gotto AM Jr, Hajjar DP
The Journal of biological chemistry 2001 May 11;276(19):16567-72
The Journal of biological chemistry 2001 May 11;276(19):16567-72
Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid.
Husemann J, Loike JD, Kodama T, Silverstein SC
Journal of neuroimmunology 2001 Mar 1;114(1-2):142-50
Journal of neuroimmunology 2001 Mar 1;114(1-2):142-50
Differentiation-dependent expression and localization of the class B type I scavenger receptor in intestine.
Cai SF, Kirby RJ, Howles PN, Hui DY
Journal of lipid research 2001 Jun;42(6):902-9
Journal of lipid research 2001 Jun;42(6):902-9
High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion.
Silver DL, Wang N, Xiao X, Tall AR
The Journal of biological chemistry 2001 Jul 6;276(27):25287-93
The Journal of biological chemistry 2001 Jul 6;276(27):25287-93
Scavenger receptor class B type I-mediated reverse cholesterol transport is inhibited by advanced glycation end products.
Ohgami N, Nagai R, Miyazaki A, Ikemoto M, Arai H, Horiuchi S, Nakayama H
The Journal of biological chemistry 2001 Apr 20;276(16):13348-55
The Journal of biological chemistry 2001 Apr 20;276(16):13348-55
Scavenger receptor-BI inhibits ATP-binding cassette transporter 1- mediated cholesterol efflux in macrophages.
Chen W, Silver DL, Smith JD, Tall AR
The Journal of biological chemistry 2000 Oct 6;275(40):30794-800
The Journal of biological chemistry 2000 Oct 6;275(40):30794-800
Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.
Wang N, Silver DL, Costet P, Tall AR
The Journal of biological chemistry 2000 Oct 20;275(42):33053-8
The Journal of biological chemistry 2000 Oct 20;275(42):33053-8
Sterol carrier protein-2 alters high density lipoprotein-mediated cholesterol efflux.
Atshaves BP, Starodub O, McIntosh A, Petrescu A, Roths JB, Kier AB, Schroeder F
The Journal of biological chemistry 2000 Nov 24;275(47):36852-61
The Journal of biological chemistry 2000 Nov 24;275(47):36852-61
Regulation by vitamin E of the scavenger receptor BI in rat liver and HepG2 cells.
Witt W, Kolleck I, Fechner H, Sinha P, Rüstow B
Journal of lipid research 2000 Dec;41(12):2009-16
Journal of lipid research 2000 Dec;41(12):2009-16
High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach.
Frolov A, Petrescu A, Atshaves BP, So PT, Gratton E, Serrero G, Schroeder F
The Journal of biological chemistry 2000 Apr 28;275(17):12769-80
The Journal of biological chemistry 2000 Apr 28;275(17):12769-80
Decreased selective uptake of high density lipoprotein cholesteryl esters in apolipoprotein E knock-out mice.
Arai T, Rinninger F, Varban L, Fairchild-Huntress V, Liang CP, Chen W, Seo T, Deckelbaum R, Huszar D, Tall AR
Proceedings of the National Academy of Sciences of the United States of America 1999 Oct 12;96(21):12050-5
Proceedings of the National Academy of Sciences of the United States of America 1999 Oct 12;96(21):12050-5
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
