251406

antibody from Abbiotec

Targeting: SFTPB SFTP3, SP-B

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

251406

Provider

Abbiotec

Proper citation

Abbiotec Cat#251406, RRID:AB_10637084

Product name

SP-B (Rodent) Antibody

Antibody type

Polyclonal

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse SP-B.

Description

Pulmonary surfactant-associated proteins (SP-B) promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. Genetic variations in SP-B are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS). RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'.

Reactivity

Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Store at -20C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.