Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- 348003 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#348003, RRID:AB_10559756
- Product name
- PE anti-human Granulysin
- Antibody type
- Monoclonal
- Antigen
- Recombinant 9 kD granulysin
- Description
- Granulysin is a member of the saposin-like protein family of lipid binding proteins (SAPLIP). It is expressed by NK cells and cytolytic T lymphocytes (CTL) as 15- and 9-kD forms. The 9-kda form is derived from the 15-kD form by cleavage at both amino- and carboxy-termini. Granulysin has broad cytolytic activities against a variety of tumor cells and microbes, including Gram-positive and -negative bacteria, fungi, and parasites. It also functions as a chemoattractant for inflammatory cells and activates the cells to express cytokines and chemokines.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-α-mediated antitumor reactivity.
Kalb ML, Glaser A, Stary G, Koszik F, Stingl G
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1583-91
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1583-91
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- BioLegend (provider)
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- Experimental details
- PE anti-human Granulysin
- Conjugate
- Yellow dye