20787-1-AP

antibody from Proteintech Group

Targeting: SMO FZD11, SMOH

Provider product page for 20787-1-AP

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [18]
Comments [0]
Validations
Immunohistochemistry [1]

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Product number: 20787-1-AP - Provider product page
Provider: Proteintech Group
Product name: SMO antibody
Antibody type: Polyclonal
Description: SMO antibody (Cat. #20787-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

SMO protein structure - 20787-1-AP shown in red.

Submitted references Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.

Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806

Repurposing of posaconazole as a hedgehog/SMO signaling inhibitor for embryonal rhabdomyosarcoma therapy.

Sun J, Lin W, Li C, Ueki H, Xue R, Sadahira T, Hu H, Wada K, Li N, Liu C, Araki M, Xu A, Huang P
American journal of cancer research 2021;11(9):4528-4540

Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.

Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920

Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.

Gu Y, Wang Y, He L, Zhang J, Zhu X, Liu N, Wang J, Lu T, He L, Tian Y, Fan Z
Molecular cancer 2021 Oct 14;20(1):132

GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer.

Ichimiya S, Onishi H, Nagao S, Koga S, Sakihama K, Nakayama K, Fujimura A, Oyama Y, Imaizumi A, Oda Y, Nakamura M
Oncology reports 2021 Mar;45(3):997-1010

Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.

Zhang Z, Xue Z, Yang H, Zhao F, Liu C, Chen J, Lu S, Zou Z, Zhou Y, Zhang X
Food & function 2021 Mar 1;12(4):1803-1817

Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.

Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR
The Journal of cell biology 2021 Jan 4;220(1)

Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.

Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348

Primary cilium remodeling mediates a cell signaling switch in differentiating neurons.

Toro-Tapia G, Das RM
Science advances 2020 May;6(21):eabb0601

Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals.

Findakly S, Choudhury A, Daggubati V, Pekmezci M, Lang UE, Raleigh DR
Acta neuropathologica communications 2020 Jul 20;8(1):114

Exosomal Sonic Hedgehog derived from cancer-associated fibroblasts promotes proliferation and migration of esophageal squamous cell carcinoma.

Zhao G, Li H, Guo Q, Zhou A, Wang X, Li P, Zhang S
Cancer medicine 2020 Apr;9(7):2500-2513

Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.

Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791

TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.

Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, Ju G, Huang J, Ge W, Chen Y, Lu Z, Wang H
Nature communications 2019 Jun 28;10(1):2863

Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.

Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578

Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.

Song L, Chen X, Wang P, Gao S, Qu C, Liu L
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596

Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.

Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, Han Y, Li L, Li Q
Chemico-biological interactions 2018 Dec 25;296:145-153

Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.

Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527

Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.

Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The SMO antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SMO. This antibody recognizes human antigen. The SMO antibody has been validated for the following applications: ELISA, IHC analysis.
Appendix: 20787-1-AP.pdf

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