Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- 20787-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SMO antibody
- Antibody type
- Polyclonal
- Description
- SMO antibody (Cat. #20787-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Repurposing of posaconazole as a hedgehog/SMO signaling inhibitor for embryonal rhabdomyosarcoma therapy.
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.
GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer.
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Primary cilium remodeling mediates a cell signaling switch in differentiating neurons.
Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals.
Exosomal Sonic Hedgehog derived from cancer-associated fibroblasts promotes proliferation and migration of esophageal squamous cell carcinoma.
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806
Frontiers in cell and developmental biology 2021;9:679806
Repurposing of posaconazole as a hedgehog/SMO signaling inhibitor for embryonal rhabdomyosarcoma therapy.
Sun J, Lin W, Li C, Ueki H, Xue R, Sadahira T, Hu H, Wada K, Li N, Liu C, Araki M, Xu A, Huang P
American journal of cancer research 2021;11(9):4528-4540
American journal of cancer research 2021;11(9):4528-4540
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.
Gu Y, Wang Y, He L, Zhang J, Zhu X, Liu N, Wang J, Lu T, He L, Tian Y, Fan Z
Molecular cancer 2021 Oct 14;20(1):132
Molecular cancer 2021 Oct 14;20(1):132
GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer.
Ichimiya S, Onishi H, Nagao S, Koga S, Sakihama K, Nakayama K, Fujimura A, Oyama Y, Imaizumi A, Oda Y, Nakamura M
Oncology reports 2021 Mar;45(3):997-1010
Oncology reports 2021 Mar;45(3):997-1010
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Zhang Z, Xue Z, Yang H, Zhao F, Liu C, Chen J, Lu S, Zou Z, Zhou Y, Zhang X
Food & function 2021 Mar 1;12(4):1803-1817
Food & function 2021 Mar 1;12(4):1803-1817
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.
Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR
The Journal of cell biology 2021 Jan 4;220(1)
The Journal of cell biology 2021 Jan 4;220(1)
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
Primary cilium remodeling mediates a cell signaling switch in differentiating neurons.
Toro-Tapia G, Das RM
Science advances 2020 May;6(21):eabb0601
Science advances 2020 May;6(21):eabb0601
Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals.
Findakly S, Choudhury A, Daggubati V, Pekmezci M, Lang UE, Raleigh DR
Acta neuropathologica communications 2020 Jul 20;8(1):114
Acta neuropathologica communications 2020 Jul 20;8(1):114
Exosomal Sonic Hedgehog derived from cancer-associated fibroblasts promotes proliferation and migration of esophageal squamous cell carcinoma.
Zhao G, Li H, Guo Q, Zhou A, Wang X, Li P, Zhang S
Cancer medicine 2020 Apr;9(7):2500-2513
Cancer medicine 2020 Apr;9(7):2500-2513
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, Ju G, Huang J, Ge W, Chen Y, Lu Z, Wang H
Nature communications 2019 Jun 28;10(1):2863
Nature communications 2019 Jun 28;10(1):2863
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
International journal of food sciences and nutrition 2019 Aug;70(5):570-578
Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway.
Song L, Chen X, Wang P, Gao S, Qu C, Liu L
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Acta biochimica et biophysica Sinica 2018 Jun 1;50(6):586-596
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, Han Y, Li L, Li Q
Chemico-biological interactions 2018 Dec 25;296:145-153
Chemico-biological interactions 2018 Dec 25;296:145-153
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, Yu D, Zhong C
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Biochemical and biophysical research communications 2017 Nov 4;493(1):521-527
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Zhu JY, Yang X, Chen Y, Jiang Y, Wang SJ, Li Y, Wang XQ, Meng Y, Zhu MM, Ma X, Huang C, Wu R, Xie CF, Li XT, Geng SS, Wu JS, Zhong CY, Han HY
Phytotherapy research : PTR 2017 Apr;31(4):680-688
Phytotherapy research : PTR 2017 Apr;31(4):680-688
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SMO antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SMO. This antibody recognizes human antigen. The SMO antibody has been validated for the following applications: ELISA, IHC analysis.