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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB4785 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4785, RRID:AB_1577352
- Product name
- MMP17 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of MMP17.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue.
Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase.
Catalytic activities and substrate specificity of the human membrane type 4 matrix metalloproteinase catalytic domain.
Jung M, Römer A, Keyszer G, Lein M, Kristiansen G, Schnorr D, Loening SA, Jung K
The Prostate 2003 May 1;55(2):89-98
The Prostate 2003 May 1;55(2):89-98
Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase.
Itoh Y, Kajita M, Kinoh H, Mori H, Okada A, Seiki M
The Journal of biological chemistry 1999 Nov 26;274(48):34260-6
The Journal of biological chemistry 1999 Nov 26;274(48):34260-6
Catalytic activities and substrate specificity of the human membrane type 4 matrix metalloproteinase catalytic domain.
Wang Y, Johnson AR, Ye QZ, Dyer RD
The Journal of biological chemistry 1999 Nov 12;274(46):33043-9
The Journal of biological chemistry 1999 Nov 12;274(46):33043-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of MMP17 polyclonal antibody (Cat # PAB4785) in NCI-H460 cell lysate (35 ug/lane). MMP17 (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with MMP17 polyclonal antibody (Cat # PAB4785) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
