20986-1-AP

antibody from Proteintech Group

Targeting: ULK1 ATG1, ATG1A

Provider product page for 20986-1-AP

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Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
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Product number: 20986-1-AP - Provider product page
Provider: Proteintech Group
Product name: ULK1 antibody
Antibody type: Polyclonal
Description: KD/KO validated ULK1 antibody (Cat. #20986-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ULK1 protein structure - 20986-1-AP shown in red.

Submitted references Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.

Hu C, Cao Y, Li P, Tang X, Yang M, Gu S, Xiong K, Li T, Xiao T
Journal of oncology 2021;2021:8281718

Taurine Alleviates Streptococcus uberis-Induced Inflammation by Activating Autophagy in Mammary Epithelial Cells.

Wang Z, Lan R, Xu Y, Zuo J, Han X, Phouthapane V, Luo Z, Miao J
Frontiers in immunology 2021;12:631113

Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.

Wang Y, Lu H, Sun L, Chen X, Wei H, Suo C, Feng J, Yuan M, Shen S, Jia W, Wang Y, Zhang H, Li Z, Zhong X, Gao P
Cell death & disease 2021 Oct 2;12(10):902

Co-modification with MSC membrane and PDA prevents Fe₃O₄-induced pulmonary toxicity in mice via AMPK-ULK1 axis.

Yao H, Yan J, Shao P, Wang Y, Liu T, Jiang J, Liu T
Toxicology letters 2021 Oct 15;351:145-154

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis.

Su H, Yang F, Fu R, Li X, French R, Mose E, Pu X, Trinh B, Kumar A, Liu J, Antonucci L, Todoric J, Liu Y, Hu Y, Diaz-Meco MT, Moscat J, Metallo CM, Lowy AM, Sun B, Karin M
Cancer cell 2021 May 10;39(5):678-693.e11

Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner.

Karabiyik C, Vicinanza M, Son SM, Rubinsztein DC
Developmental cell 2021 Jul 12;56(13):1961-1975.e5

lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.

Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620

Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.

Xiaoli F, Yaqing Z, Ruhui L, Xuan L, Aijie C, Yanli Z, Chen H, Lili C, Longquan S
Journal of hazardous materials 2021 Aug 15;416:126158

Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.

Li Q, Luan Q, Zhu H, Zhao Y, Ji J, Wu F, Yan J
Biochemical and biophysical research communications 2021 Apr 30;551:78-85

Inhibition of Brd4 by JQ1 Promotes Functional Recovery From Spinal Cord Injury by Activating Autophagy.

Li Y, Xiang J, Zhang J, Lin J, Wu Y, Wang X
Frontiers in cellular neuroscience 2020;14:555591

The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.

Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X
OncoTargets and therapy 2020;13:473-486

Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.

Fan L, Wang J, Cao Q, Ding X, Li B
American journal of cancer research 2020;10(1):314-335

The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy.

Jin C, Miao X, Zhong Y, Han J, Liu Q, Zhu J, Xia X, Peng X
Food & function 2020 Sep 23;11(9):7456-7467

Topology-dependent, bifurcated mitochondrial quality control under starvation.

Zhou Y, Long Q, Wu H, Li W, Qi J, Wu Y, Xiang G, Tang H, Yang L, Chen K, Li L, Bao F, Li H, Wang Y, Li M, Liu X
Autophagy 2020 Mar;16(3):562-574

NeuroHeal Treatment Alleviates Neuropathic Pain and Enhances Sensory Axon Regeneration.

Romeo-Guitart D, Casas C
Cells 2020 Mar 27;9(4)

COX5B-Mediated Bioenergetic Alteration Regulates Tumor Growth and Migration by Modulating AMPK-UHMK1-ERK Cascade in Hepatoma.

Chu YD, Lin WR, Lin YH, Kuo WH, Tseng CJ, Lim SN, Huang YL, Huang SC, Wu TJ, Lin KH, Yeh CT
Cancers 2020 Jun 22;12(6)

Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy.

Xu D, Liu J, Ma H, Guo W, Wang J, Kan X, Li Y, Gong Q, Cao Y, Cheng J, Fu S
International immunopharmacology 2020 Jan;78:105983

Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.

Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, He G, Han B
Cell proliferation 2020 Jan;53(1):e12701

CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus.

Wu Q, Zhang M, Liu X, Zhang J, Wang H
International journal of molecular medicine 2020 Feb;45(2):475-484

The antidepressant effects of apigenin are associated with the promotion of autophagy via the mTOR/AMPK/ULK1 pathway.

Zhang X, Bu H, Jiang Y, Sun G, Jiang R, Huang X, Duan H, Huang Z, Wu Q
Molecular medicine reports 2019 Sep;20(3):2867-2874

ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint.

Yuan F, Jin X, Li D, Song Y, Zhang N, Yang X, Wang L, Zhu WG, Tian C, Zhao Y
Nucleic acids research 2019 Sep 5;47(15):8096-8110

A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.

Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032

Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.

Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, Jiang Q
Food & function 2019 May 22;10(5):2651-2657

Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis, Endothelial Dysfunction, and Corporal Fibrosis.

Lin H, Wang T, Ruan Y, Liu K, Li H, Wang S, Li M, Liu J
The journal of sexual medicine 2018 Sep;15(9):1246-1259

Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.

Luo X, Wang D, Zhu X, Wang G, You Y, Ning Z, Li Y, Jin S, Huang Y, Hu Y, Chen T, Meng Y, Li X
Cell death & disease 2018 May 1;9(5):576

Luo X, Dan Wang, Luo X, Zhu X, Wang G, Ning Z, Li Y, Ma X, Yang R, Jin S, Huang Y, Meng Y, Li X
Redox biology 2017 Oct;13:508-521

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