DPABH-25938

antibody from Creative Diagnostics

Targeting: CHMP2B CHMP2.5, DKFZP564O123, VPS2B

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-25938

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-25938, RRID:AB_2518987

Product name

Rabbit Anti-Human CHMP2B Polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL