Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN151041 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 3C5-1
- Vial size
- 0.05 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Stimulation of human DNA polymerase epsilon by MDM2.
MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon.
Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis.
Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon.
Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis.
Processing of an HIV replication intermediate by the human DNA replication enzyme FEN1.
Replication protein A stimulates long patch DNA base excision repair.
Incorporation and excision of 9-(2-phosphonylmethoxyethyl)guanine (PMEG) by DNA polymerase delta and epsilon in vitro.
Mammalian base excision repair by DNA polymerases delta and epsilon.
DNA synthesis on discontinuous templates by human DNA polymerases: implications for non-homologous DNA recombination.
Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon.
Further characterization of HeLa DNA polymerase epsilon.
Asahara H, Li Y, Fuss J, Haines DS, Vlatkovic N, Boyd MT, Linn S
Nucleic acids research 2003 May 1;31(9):2451-9
Nucleic acids research 2003 May 1;31(9):2451-9
MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon.
Vlatkovic N, Guerrera S, Li Y, Linn S, Haines DS, Boyd MT
Nucleic acids research 2000 Sep 15;28(18):3581-6
Nucleic acids research 2000 Sep 15;28(18):3581-6
Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis.
Liu W, Linn S
Nucleic acids research 2000 Nov 1;28(21):4180-8
Nucleic acids research 2000 Nov 1;28(21):4180-8
Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon.
Li Y, Pursell ZF, Linn S
The Journal of biological chemistry 2000 Jul 28;275(30):23247-52
The Journal of biological chemistry 2000 Jul 28;275(30):23247-52
Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis.
Maga G, Jónsson ZO, Stucki M, Spadari S, Hübscher U
Journal of molecular biology 1999 Jan 8;285(1):259-67
Journal of molecular biology 1999 Jan 8;285(1):259-67
Processing of an HIV replication intermediate by the human DNA replication enzyme FEN1.
Rumbaugh JA, Fuentes GM, Bambara RA
The Journal of biological chemistry 1998 Oct 30;273(44):28740-5
The Journal of biological chemistry 1998 Oct 30;273(44):28740-5
Replication protein A stimulates long patch DNA base excision repair.
DeMott MS, Zigman S, Bambara RA
The Journal of biological chemistry 1998 Oct 16;273(42):27492-8
The Journal of biological chemistry 1998 Oct 16;273(42):27492-8
Incorporation and excision of 9-(2-phosphonylmethoxyethyl)guanine (PMEG) by DNA polymerase delta and epsilon in vitro.
Kramata P, Downey KM, Paborsky LR
The Journal of biological chemistry 1998 Aug 21;273(34):21966-71
The Journal of biological chemistry 1998 Aug 21;273(34):21966-71
Mammalian base excision repair by DNA polymerases delta and epsilon.
Stucki M, Pascucci B, Parlanti E, Fortini P, Wilson SH, Hübscher U, Dogliotti E
Oncogene 1998 Aug 20;17(7):835-43
Oncogene 1998 Aug 20;17(7):835-43
DNA synthesis on discontinuous templates by human DNA polymerases: implications for non-homologous DNA recombination.
Islas L, Fairley CF, Morgan WF
Nucleic acids research 1998 Aug 15;26(16):3729-38
Nucleic acids research 1998 Aug 15;26(16):3729-38
Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon.
Li Y, Asahara H, Patel VS, Zhou S, Linn S
The Journal of biological chemistry 1997 Dec 19;272(51):32337-44
The Journal of biological chemistry 1997 Dec 19;272(51):32337-44
Further characterization of HeLa DNA polymerase epsilon.
Chui G, Linn S
The Journal of biological chemistry 1995 Apr 7;270(14):7799-808
The Journal of biological chemistry 1995 Apr 7;270(14):7799-808
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