CABT-BL3268

antibody from Creative Diagnostics

Targeting: SDHD cybS, PGL, PGL1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-BL3268

Provider

Creative Diagnostics

Product name

Anti-SDHD monoclonal antibody, clone 4G5

Antibody type

Monoclonal

Description

This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4G5

Storage

Store at -2°C or lower. Aliquot to avoid repeated freezing and thawing.