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- References [7]
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- Product number
- ABIN565913 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Checkpoint with Forkhead and Ring Finger Domains, E3 Ubiquitin Protein Ligase (CHFR) (AA 1-652), (full length) antibody
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-652, full length
- Isotype
- IgG
- Antibody clone number
- 1H3-A12
- Vial size
- 100 μg
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Handling
- Aliquot to avoid repeated freezing and thawing.
Submitted references Expression level of the mitotic checkpoint protein and G2-M cell cycle regulators and prognosis in gastrointestinal stromal tumors in the stomach.
CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation.
Pathobiologic implications of methylation and expression status of Runx3 and CHFR genes in gastric cancer.
Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint.
Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma.
Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis.
Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression.
Fujita A, Yamamoto H, Imamura M, Nakamura N, Maehara Y, Tsuneyoshi M, Oda Y
Virchows Archiv : an international journal of pathology 2012 Feb;460(2):163-9
Virchows Archiv : an international journal of pathology 2012 Feb;460(2):163-9
CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation.
Kashima L, Idogawa M, Mita H, Shitashige M, Yamada T, Ogi K, Suzuki H, Toyota M, Ariga H, Sasaki Y, Tokino T
The Journal of biological chemistry 2012 Apr 13;287(16):12975-84
The Journal of biological chemistry 2012 Apr 13;287(16):12975-84
Pathobiologic implications of methylation and expression status of Runx3 and CHFR genes in gastric cancer.
Hu SL, Huang DB, Sun YB, Wu L, Xu WP, Yin S, Chen J, Jiang XD, Shen G
Medical oncology (Northwood, London, England) 2011 Jun;28(2):447-54
Medical oncology (Northwood, London, England) 2011 Jun;28(2):447-54
Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint.
Privette LM, Weier JF, Nguyen HN, Yu X, Petty EM
Neoplasia (New York, N.Y.) 2008 Jul;10(7):643-52
Neoplasia (New York, N.Y.) 2008 Jul;10(7):643-52
Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma.
Gao YJ, Xin Y, Zhang JJ, Zhou J
World journal of gastroenterology 2008 Aug 28;14(32):5000-7
World journal of gastroenterology 2008 Aug 28;14(32):5000-7
Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis.
Milne AN, Sitarz R, Carvalho R, Polak MM, Ligtenberg M, Pauwels P, Offerhaus GJ, Weterman MA
Human pathology 2007 Jun;38(6):903-13
Human pathology 2007 Jun;38(6):903-13
Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression.
Privette LM, González ME, Ding L, Kleer CG, Petty EM
Cancer research 2007 Jul 1;67(13):6064-74
Cancer research 2007 Jul 1;67(13):6064-74
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Supportive validation
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