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- References [10]
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- Western blot [1]
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- Product number
- 21668-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21668-1-AP, RRID:AB_10793724
- Product name
- SESN1 antibody
- Antibody type
- Polyclonal
- Description
- SESN1 antibody (Cat. #21668-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exercise improves lipid metabolism disorders induced by high-fat diet in a SESN2/JNK-independent manner.
Inhibition of mTORC1 through ATF4-induced REDD1 and Sestrin2 expression by Metformin.
SAR1B senses leucine levels to regulate mTORC1 signalling.
Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice.
Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle.
Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy.
Repressors of mTORC1 act to blunt the anabolic response to feeding in the soleus muscle of a cast-immobilized mouse hindlimb.
Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins.
Suppression of Sestrins in aging and osteoarthritic cartilage: dysfunction of an important stress defense mechanism.
Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling.
Wang T, Hu W, Niu Y, Liu S, Fu L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2021 Nov;46(11):1322-1330
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2021 Nov;46(11):1322-1330
Inhibition of mTORC1 through ATF4-induced REDD1 and Sestrin2 expression by Metformin.
Jang SK, Hong SE, Lee DH, Kim JY, Kim JY, Ye SK, Hong J, Park IC, Jin HO
BMC cancer 2021 Jul 12;21(1):803
BMC cancer 2021 Jul 12;21(1):803
SAR1B senses leucine levels to regulate mTORC1 signalling.
Chen J, Ou Y, Luo R, Wang J, Wang D, Guan J, Li Y, Xia P, Chen PR, Liu Y
Nature 2021 Aug;596(7871):281-284
Nature 2021 Aug;596(7871):281-284
Pentamethylquercetin Attenuates Cardiac Remodeling via Activation of the Sestrins/Keap1/Nrf2 Pathway in MSG-Induced Obese Mice.
Du J, He W, Zhang C, Wu J, Li Z, Wang M, Feng S, Liang G
BioMed research international 2020;2020:3243906
BioMed research international 2020;2020:3243906
Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle.
Xu D, Shimkus KL, Lacko HA, Kutzler L, Jefferson LS, Kimball SR
American journal of physiology. Endocrinology and metabolism 2019 May 1;316(5):E817-E828
American journal of physiology. Endocrinology and metabolism 2019 May 1;316(5):E817-E828
Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy.
Tu J, Li W, Li S, Liu W, Zhang Y, Wu X, Luo R, Hua W, Wang K, Song Y, Kang L, Yang W, Yang S, Yang C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(5):1940-1954
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(5):1940-1954
Repressors of mTORC1 act to blunt the anabolic response to feeding in the soleus muscle of a cast-immobilized mouse hindlimb.
Shimkus KL, Jefferson LS, Gordon BS, Kimball SR
Physiological reports 2018 Oct;6(20):e13891
Physiological reports 2018 Oct;6(20):e13891
Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins.
Wang T, Niu Y, Liu S, Yuan H, Liu X, Fu L
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3368-3377
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3368-3377
Suppression of Sestrins in aging and osteoarthritic cartilage: dysfunction of an important stress defense mechanism.
Shen T, Alvarez-Garcia O, Li Y, Olmer M, Lotz MK
Osteoarthritis and cartilage 2017 Feb;25(2):287-296
Osteoarthritis and cartilage 2017 Feb;25(2):287-296
Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling.
Tao R, Xiong X, Liangpunsakul S, Dong XC
Diabetes 2015 Apr;64(4):1211-23
Diabetes 2015 Apr;64(4):1211-23
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The SESN1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SESN1. This antibody recognizes human,mouse,rat antigen. The SESN1 antibody has been validated for the following applications: ELISA, WB analysis.
