AMM04291G

antibody from Leading Biology

Targeting: UNC13D Munc13-4

Western blot (Recommended by provider)

Antibody Data

Product number

AMM04291G

Provider

Leading Biology

Product name

UNC13D Antibody (monoclonal) (M05)

Antibody type

Monoclonal

Description

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

2C7

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.