Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APG00206G - Provider product page
- Provider
- Leading Biology
- Product name
- Goat Anti-Munc13-4 / UNC13D (Internal) Antibody
- Antibody type
- Polyclonal
- Description
- This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
- Reactivity
- Human, Mouse
- Host
- Goat
- Isotype
- IgG
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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