Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 12030-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12030-1-AP, RRID:AB_11183770
- Product name
- WBP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated WBP2 antibody (Cat. #12030-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury.
EIF4A3-mediated circPRKCI expression promotes triple-negative breast cancer progression by regulating WBP2 and PI3K/AKT signaling pathway.
WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1.
Itch attenuates CD4 T-cell proliferation in mice by limiting WBP2 protein stability.
The perforatorium and postacrosomal sheath of rat spermatozoa share common developmental origins and protein constituents†.
WBP2 shares a common location in mouse spermatozoa with WBP2NL/PAWP and like its descendent is a candidate mouse oocyte-activating factor.
Deng Z, Wang Y, Liu J, Zhang H, Zhou L, Zhao H, Han Y, Yan S, Dong Z, Wang Y, Dai Y, Deng F
Redox biology 2023 Sep;65:102826
Redox biology 2023 Sep;65:102826
EIF4A3-mediated circPRKCI expression promotes triple-negative breast cancer progression by regulating WBP2 and PI3K/AKT signaling pathway.
Wang X, Song H, Fang L, Wu T
Cell death discovery 2022 Mar 2;8(1):92
Cell death discovery 2022 Mar 2;8(1):92
WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1.
Zheng Z, Li Y, Fan S, An J, Luo X, Liang M, Zhu F, Huang K
Cell death & disease 2021 Mar 3;12(3):228
Cell death & disease 2021 Mar 3;12(3):228
Itch attenuates CD4 T-cell proliferation in mice by limiting WBP2 protein stability.
Field NS, Elbulok OA, Dybas JM, Moser EK, Dar AA, Spruce LA, Fazelinia H, Seeholzer SH, Oliver PM
European journal of immunology 2020 Oct;50(10):1468-1483
European journal of immunology 2020 Oct;50(10):1468-1483
The perforatorium and postacrosomal sheath of rat spermatozoa share common developmental origins and protein constituents†.
Protopapas N, Hamilton LE, Warkentin R, Xu W, Sutovsky P, Oko R
Biology of reproduction 2019 Jun 1;100(6):1461-1472
Biology of reproduction 2019 Jun 1;100(6):1461-1472
WBP2 shares a common location in mouse spermatozoa with WBP2NL/PAWP and like its descendent is a candidate mouse oocyte-activating factor.
Hamilton LE, Suzuki J, Acteau G, Shi M, Xu W, Meinsohn MC, Sutovsky P, Oko R
Biology of reproduction 2018 Dec 1;99(6):1171-1183
Biology of reproduction 2018 Dec 1;99(6):1171-1183
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 12030-1-AP(WBP2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 12030-1-AP(WBP2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The WBP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human WBP2. This antibody recognizes human,mouse,rat antigen. The WBP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.