BS1894

antibody from Bioworld Technology, Inc
Targeting: DGKI DGK-IOTA
Provider product page for BS1894
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS1894 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1894, RRID:AB_1663570
Product name
DGK êò (K1023) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 1001-1050 of Human DGK-êò.
Description
Diacylglycerol (DAG) influences numerous cell signaling cascades by functioning as an intracellular, allosteric activator of protein kinase C (PKC), and as a potent activator of guanine nucleotide exchange factors. In order to maintain cellular homeostasis, intracellular DAG levels are tightly regulated by diacylglycerol kinases (DGKs, DAGKs), which phosphorylate DAG to phosphatidic acid, thus removing DAG. Human DGK-Ï« (80 kDa), -ÉÇ (90 kDa), and - ÎÛ (90 kDa) have calcium-binding EF-hand motifs at their N termini and are classified as type I DGKs. Human DGK-Ñ´ (130 kDa) and DGK-êò (130 kDa) contain N-terminal pleckstrin homology (PH) domains and are classified as type II. Human DGK-epsilon (64 kDa) contains no identifiable regulatory domains and is classified as a type III DGK. Human DGK-´Î (104 kDa) and -iota (130 kDa) possess C-terminal ankyrin repeats and are classified as type IV DGKs. Human DGK-IJ (110 kDa) contains 3 cysteine-rich domains and a PH domain and is classified as a type V DGK.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DGKI protein structure - BS1894 shown in red.