Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP2-13167 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal ERManI Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Innate Sensing of Influenza A Virus Hemagglutinin Glycoproteins by the Host Endoplasmic Reticulum (ER) Stress Pathway Triggers a Potent Antiviral Response via ER-Associated Protein Degradation.
ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway.
MAN1B1 deficiency: an unexpected CDG-II.
Frabutt DA, Wang B, Riaz S, Schwartz RC, Zheng YH
Journal of virology 2018 Jan 1;92(1)
Journal of virology 2018 Jan 1;92(1)
ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway.
Zhou T, Frabutt DA, Moremen KW, Zheng YH
The Journal of biological chemistry 2015 Sep 4;290(36):22184-92
The Journal of biological chemistry 2015 Sep 4;290(36):22184-92
MAN1B1 deficiency: an unexpected CDG-II.
Rymen D, Peanne R, Millón MB, Race V, Sturiale L, Garozzo D, Mills P, Clayton P, Asteggiano CG, Quelhas D, Cansu A, Martins E, Nassogne MC, Gonçalves-Rocha M, Topaloglu H, Jaeken J, Foulquier F, Matthijs G
PLoS genetics 2013;9(12):e1003989
PLoS genetics 2013;9(12):e1003989
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: ERManI Antibody (3C2) [NBP2-13167] - Western blot analysis of ERManI expression in 1) NTERA-2 and 2) A-431 whole cell lysates.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: ERManI Antibody (3C2) [NBP2-13167] - IHC staining of ERManI in human breast cancer using DAB with hematoxylin counterstain.