BS8370

antibody from Bioworld Technology, Inc
Targeting: PRPF19 hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4
Provider product page for BS8370
Western blot
Immunohistochemistry

Antibody data

Product number
BS8370 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PRPF19 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PRPF19.
Description
The spliceosome, the gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and five RNA molecules (U1, U2, U4, U5 and U6). Pre-mRNA splicing is essential to remove internal non-coding regions of pre-mRNA (introns) and to join the remaining segments (exons) into mRNA before translation. The PRP19-associated complex is required for stable association of U5 and U6 with the spliceosome after U4 is released. Changes within the spliceosome upon binding of the PRP19-associated complex include remodeling of the U6/5£ª splice site interaction and destabilization of Lsm proteins to allow further interaction of U6 with the intron sequence.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PRPF19 protein structure - BS8370 shown in red.