Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3426 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3426, RRID:AB_1574972
- Product name
- FRK polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of FRK.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Breast cancer cell line proliferation blocked by the Src-related Rak tyrosine kinase.
The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb.
Rak, a novel nuclear tyrosine kinase expressed in epithelial cells.
Meyer T, Xu L, Chang J, Liu ET, Craven RJ, Cance WG
International journal of cancer 2003 Mar 20;104(2):139-46
International journal of cancer 2003 Mar 20;104(2):139-46
The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb.
Craven RJ, Cance WG, Liu ET
Cancer research 1995 Sep 15;55(18):3969-72
Cancer research 1995 Sep 15;55(18):3969-72
Rak, a novel nuclear tyrosine kinase expressed in epithelial cells.
Cance WG, Craven RJ, Bergman M, Xu L, Alitalo K, Liu ET
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994 Dec;5(12):1347-55
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994 Dec;5(12):1347-55
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of FRK (arrow) using FRK polyclonal antibody (Cat # PAB3426).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FRK gene (Lane 2).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with FRK polyclonal antibody (Cat # PAB3426) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)