PAB4799
antibody from Abnova Corporation
Targeting: SEPTIN9
AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SEPT9, SeptD1
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB4799 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4799, RRID:AB_1580478
- Product name
- SEPT9 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of SEPT9.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Detection of methylated septin 9 in tissue and plasma of colorectal patients with neoplasia and the relationship to the amount of circulating cell-free DNA.
Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island.
Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3.
Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors.
MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25).
Tóth K, Wasserkort R, Sipos F, Kalmár A, Wichmann B, Leiszter K, Valcz G, Juhász M, Miheller P, Patai ÁV, Tulassay Z, Molnár B
PloS one 2014;9(12):e115415
PloS one 2014;9(12):e115415
Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island.
Wasserkort R, Kalmar A, Valcz G, Spisak S, Krispin M, Toth K, Tulassay Z, Sledziewski AZ, Molnar B
BMC cancer 2013 Aug 30;13:398
BMC cancer 2013 Aug 30;13:398
Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3.
McIlhatton MA, Burrows JF, Donaghy PG, Chanduloy S, Johnston PG, Russell SE
Oncogene 2001 Sep 13;20(41):5930-9
Oncogene 2001 Sep 13;20(41):5930-9
Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors.
Russell SE, McIlhatton MA, Burrows JF, Donaghy PG, Chanduloy S, Petty EM, Kalikin LM, Church SW, McIlroy S, Harkin DP, Keilty GW, Cranston AN, Weissenbach J, Hickey I, Johnston PG
Cancer research 2000 Sep 1;60(17):4729-34
Cancer research 2000 Sep 1;60(17):4729-34
MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25).
Osaka M, Rowley JD, Zeleznik-Le NJ
Proceedings of the National Academy of Sciences of the United States of America 1999 May 25;96(11):6428-33
Proceedings of the National Academy of Sciences of the United States of America 1999 May 25;96(11):6428-33
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The MAFK polyclonal antibody (Cat # PAB4799) is used in Western blot to detect MAFK in Jurkat cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with MAFK polyclonal antibody (Cat # PAB4799) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)