FNab09506

antibody from FineTest Biotech

Targeting: WEE2 FLJ16107, WEE1B

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab09506 - Provider product page
Provider: FineTest Biotech
Product name: WEE2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity).
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: WEE1 homolog 2(S. pombe)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

WEE2 protein structure - FNab09506 shown in red.